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ARS Home » Northeast Area » Orient Point, New York » Plum Island Animal Disease Center » Foreign Animal Disease Research » People & Locations » Jonathan Arzt

Jonathan Arzt
Foreign Animal Disease Research
Veterinary Medical Officer

Phone: (631) 323-4421
Fax: (631) 323-3006

40550 ROUTE 25
ORIENT POINT , NY 11957
Projects
Foot-and-mouth disease surveillance in Vietnam
Cooperative Agreement (A)
  Accession Number: 427390
Ecology of Vesicular Stomatitis Virus (VSV) in North America
In-House Appropriated (D)
  Accession Number: 431806
Countermeasures to Control and Eradicate Foreign Animal Diseases of Swine
In-House Appropriated (D)
  Accession Number: 431897
Intervention Strategies to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus (FMDV)
In-House Appropriated (D)
  Accession Number: 431980
Using Novel Experimental Data to Enhance Modeling of Foreign Animal Disease Threats to Livestock Within the US Homeland.
Interagency Reimbursable Agreement (I)
  Accession Number: 429449
Leveraging Clincal Studies at Plum Island Animal Disease Center to Improve Paramterization of Foreign Animal Disease Models
Interagency Reimbursable Agreement (I)
  Accession Number: 431065
Susceptibility of Pigs to FMD Infection via Natural Ingestion: Establishing Minimum Oral Infectious Dose and Evaluating...Mitigates
Interagency Reimbursable Agreement (I)
  Accession Number: 433971
Foot-and-Mouth Disease Virus Ecology and Surviellance in Vietnam; Exploiting Asymptomatic Carriers to Monitor Field Strains
Interagency Reimbursable Agreement (I)
  Accession Number: 427370
Longitudinal Data and Modeling to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus
Non-Funded Cooperative Agreement (N)
  Accession Number: 430633
Foreign Animal Disease Research and Development Activities to Address High Priority Transboundary Animal Diseases
Non-Funded Cooperative Agreement (N)
  Accession Number: 432658
Susceptiblity of Pigs to FMD Infection via Natural Ingestion: Establishing Minimum Oral Infectious Dose and Evaluating...Mitigants
Reimbursable Cooperative Agreement (R)
  Accession Number: 433916
Susceptibility of Pigs to FMD Infection via Natural Ingestion: Establishing Minimum Oral Infectious Dose and Evaluating...Mitigates
Reimbursable Cooperative Agreement (R)
  Accession Number: 433966
Preliminary Study for the Reversion to Virulence Study of FMDV-LL3B3D-A24 Cruzeiro in Swine
Non-Assistance Cooperative Agreement (S)
  Accession Number: 431774
Research Supporting Workforce Development for the National Bio-Agro Defense Facility: Virus-Host Interactions of Vesicular Stomatitis Virus
Non-Assistance Cooperative Agreement (S)
  Accession Number: 434104
The Impact of Acute Subclinical Foot-and-Mouth Disease Virus in Kenyan Cattle
Non-Assistance Cooperative Agreement (S)
  Accession Number: 435538
Understanding Pathogenesis and Epidemiology for Controlling Foreign Animal Diseases
Non-Assistance Cooperative Agreement (S)
  Accession Number: 433510
Quantitative Analyses of Foot-and-Mouth Disease in Endemic Regions of Asia and Africa
Non-Assistance Cooperative Agreement (S)
  Accession Number: 430966
Longitudinal Study of FMD Vaccinated and Unvaccinated Cattle in Cameroon
Non-Assistance Cooperative Agreement (S)
  Accession Number: 428784

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Phylogeographic and cross-species transmission dynamics of SAT1 and SAT2 foot-and-mouth disease virus in Eastern Africa -
Omondi, G., Alkhamis, M., Obanda, V., Gakuya, F., Sangula, A., Pauszek, S.J., Perez, A., Ngulu, S., Van Aardt, R., Arzt, J., Vanderwaal, K. 2019. Phylogeographic and cross-species transmission dynamics of SAT1 and SAT2 foot-and-mouth disease virus in Eastern Africa. Molecular Ecology. https://doi.org/10.1111/mec.15125.
The evolution of a super-swarm of foot-and-mouth disease virus in cattle -
Arzt, J., Fish, I., Pauszek, S.J., Johnson, S.L., Chain, P.S., Rai, D.K., Rieder, A.E., Goldberg, T.L., Rodriguez, L.L., Stenfeldt, C. 2019. The evolution of a super-swarm of foot-and-mouth disease virus in cattle. Virology. https://doi.org/10.1371/journal.pone.0210847.
Genetic and antigenic variation of foot-and-mouth disease virus during persistent infection in naturally infected cattle and Asian buffalo in India -
Biswal, J.K., Ranjan, R., Subramaniam, S., Mohapatra, J.K., Sharma, M.K., Bertram, M.R., Brito, B., Rodriguez, L.L., Pattnaik, B., Arzt, J. 2019. Genetic and antigenic variation of foot-and-mouth disease virus during persistent infection in naturally infected cattle and Asian buffalo in India. bioRxiv. https://doi.org/10.1101/586644.
Validation of a site-specific recombination cloning technique for the rapid development of an infectious cDNA clone of a virulent field strain of vesicular stomatitis New Jersey virus -
Velazquez-Salinas, L., Pauszek, S.J., Barrera, J., Clark, B., Borca, M.V., Verdugo-Rodriguez, A., Arzt, J., Rodriguez, L.L. 2019. Validation of a site-specific recombination cloning technique for the rapid development of an infectious cDNA clone of a virulent field strain of vesicular stomatitis New Jersey virus. Journal of Virological Methods. Volume 265, March 2019, Pages 113-116. https://doi.org/10.1016/j.jviromet.2019.01.003.
Quantitative impacts of incubation phase transmission of foot-and-mouth disease virus -
Arzt, J., Branan, M., Delgado, A., Yadav, S., Moreno-Torres, K., Tildesley, M., Stenfeldt, C. 2019. Quantitative impacts of incubation phase transmission of foot-and-mouth disease virus. Scientific Reports. https://doi.org/10.1038/s41598-019-39029-0.
First genome sequence of Foot-and-mouth disease virus serotype O sublineage Ind2001e from Vietnam -
Palinski, R., Bertram, M.R., Vu, L.T., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Stenfeldt, C., Fish, I.H., Hoang, B.H., Dung, D.H., Arzt, J. 2019. First genome sequence of Foot-and-mouth disease virus serotype O sublineage Ind2001e from Vietnam. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.01424-18.
First detection of Senecavirus A in Vietnam -
Arzt, J., Bertram, M.R., Vu, L.T., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Palinski, R., Stenfeldt, C., Fish, I.H., Hoang, B.H., Dung, D.H. 2019. First detection of Senecavirus A in Vietnam. Emerging Infectious Diseases. https://doi.org/10.1128/MRA.01247-18.
Molecular epidemiology of foot-and-mouth disease virus in the context of transboundary animal movement in the far north region of Cameroon -
Bertram, M., Bravo De Rueda, C., Garabed, R., Dickmu Jumbo, S., Moritz, M., Pauszek, S.J., Abdoulkadiri, S., Rodriguez, L.L., Arzt, J. 2018. Molecular epidemiology of foot-and-mouth disease virus in the context of transboundary animal movement in the far north region of Cameroon. Frontiers in Veterinary Infectious Diseases. https://doi.org/10.3389/fvets.2018.00320.
Contact challenge of cattle with foot-and-mouth disease virus validates the role of the nasopharyngeal epithelium as the site of primary and persistent infection. -
Stenfeldt, C., Smoliga, G.R., Hartwig, E.J., Palinski, R., Fish, I.H., Silva, E.B., Pauszek, S.J., Arzt, J. 2018. Contact challenge of cattle with foot-and-mouth disease virus validates the role of the nasopharyngeal epithelium as the site of primary and persistent infection. Scientific Reports. https://doi.org/10.1128/mSphere.00493-18.
The different tactics of foot-and-mouth disease virus to evade innate immunity -
Medina, G.N., Diaz San-Segundo, F., Stenfeldt, C., Arzt, J., De los Santos, T.B. 2018. The different tactics of foot-and-mouth disease virus to evade innate immunity. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2018.02644.
Transmission of foot-and-mouth disease from persistently infected carrier cattle to naive cattle via transfer of oropharyngeal fluid -
Arzt, J., Belsham, G.J., Lohse, L., Botner, A., Stenfeldt, C. 2018. Transmission of foot-and-mouth disease from persistently infected carrier cattle to naive cattle via transfer of oropharyngeal fluid. mSphere. 3(5):e00365-18. https://doi.org/10.1128/mSphere.00365-18.
Characterization of naturally occurring, acute and persistent subclinical foot-and-mouth disease virus infection in vaccinated Asian buffalo in Pakistan -
Increased virulence of an epidemic strain of vesicular stomatitis virus is associated with interference of the innate response in pigs -
Velazquez-Salinas, L., Pauszek, S.J., Stenfeldt, C., O'Hearn, E.S., Pacheco, J.M., Borca, M.V., Verdugo-Rodriguez, A., Arzt, J., Rodriguez, L.L. 2018. Increased virulence of an epidemic strain of vesicular stomatitis virus is associated with interference of the innate response in pigs. Frontiers in Microbiology. 9:1891. https://doi.org/10.3389/fmicb.2018.01891.
Lack of transmission of foot-and-mouth disease virus from persistently infected cattle to naïve cattle under field conditions in Vietnam -
Bertram, M.R., Vu, L.T., Pauszek, S.J., Brito, B.P., Hartwig, E.J., Smoliga, G.R., Hoang, B.H., Phuong, N.T., Stenfeldt, C., Fish, I.H., Hung, V.V., Delgado, A., VanderWaal, K., Rodriguez, L.L., Long, N.T., Dung, D.H., Arzt, J. 2018. Lack of transmission of foot-and-mouth disease virus from persistently infected cattle to naïve cattle under field conditions in Vietnam. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2018.00174.
Foot-and-mouth disease infection dynamics in contact-exposed pigs are determined by the estimated exposure dose -
Moreno-Torres, K.I., Brito, B.P., Branan, M.A., Rodriguez, L.L., Delgado, A.H., Stenfeldt, C., Arzt, J. 2018. Foot-and-mouth disease infection dynamics in contact-exposed pigs are determined by the estimated exposure dose. Frontiers in Veterinary Science. 5:167. https://doi.org/10.3389/fvets.2018.00167.
Characterization of naturally occurring, new and persistent subclinical foot-and-mouth disease virus infection in vaccinated Asian buffalo in Islamabad Capital Territory, Pakistan -
Farooq, U., Ahmed, Z., Naeem, K., Bertram, M., Brito, B., Stenfeldt, C., Pauszek, S.J., Larocco, M.A., Arzt, J., Rodriguez, L.L. 2018. Characterization of naturally occurring, new and persistent subclinical foot-and-mouth disease virus infection in vaccinated Asian buffalo in Islamabad Capital Territory, Pakistan. Veterinary Research. https://doi.org/10.1111/tbed.12963.
A traditional evolutionary history of foot-and-mouth disease viruses in Southeast Asia challenged by analyses of non-structural protein coding sequences -
Brito, B.P., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Vu, P.P., Stenfeldt, C., Rodriguez, L.L., King, D.P., Knowles, N.J., Bachanek-Bankowska, K., Long, N.T., Dung, D.H., Arzt, J. 2018. A traditional evolutionary history of foot-and-mouth disease viruses in Southeast Asia challenged by analyses of non-structural protein coding sequences. Scientific Reports. 8:6472. https://doi.org/10.1038/s41598-018-24870-6.
Effect of vaccination on cattle herds previously exposed to foot and mouth disease in Cameroon -
Bertram, M.R., Delgado, A., Pauszek, S.J., Smoliga, G.R., Brito, B.P., Stenfeldt, C., Hartwig, E.J., Dickmu-Jumbo, S., Abdoulmoumini, M., Abona Olivia, A., Salhine, R., Rodriguez, L.L., Gerabed, R., Arzt, J. 2018. Effect of vaccination on cattle herds previously exposed to foot and mouth disease in Cameroon. Preventive Veterinary Medicine. 155:1-10. https://doi.org/10.1016/j.prevetmed.2018.04.003.
Evidence of subclinical foot-and-mouth disease virus infection in young calves born from clinically recovered cow under natural condition -
Ranjan, R., Biswal, J.K., Subramaniam, S., Dash, B.B., Singh, K.P., Arzt, J., Rodriguez, L.L., Pattnaik, B. 2018. Evidence of subclinical foot-and-mouth disease virus infection in young calves born from clinically recovered cow under natural condition. Tropical Animal Health and Production. https://doi.org/10.1007/s11250-018-1518-6.
A partial deletion within foot-and-mouth disease virus non-structural protein 3A causes clinical attenuation in cattle but does not prevent subclinical infection -
Stenfeldt, C., Arzt, J., Pacheco, J., Gladue, D.P., Smoliga, G.R., Silva, E., Rodriguez, L.L., Borca, M.V. 2018. A partial deletion within foot-and-mouth disease virus non-structural protein 3A causes clinical attenuation in cattle but does not prevent subclinical infection. Virology. 516:115-126. https://doi.org/10.1016/j.virol.2018.01.008.
Clearance of a persistent Picornavirus infection is associated with enhanced pro-apoptotic and cellular immune responses -
Stenfeldt, C., Eschbaumer, M., Smoliga, G.R., Rodriguez, L.L., Zhu, J.J., Arzt, J. 2017. Clearance of a persistent Picornavirus infection is associated with enhanced pro-apoptotic and cellular immune responses. Scientific Reports. 7:17800. https://doi.org/10.1038/s41598-017-18112-4.
Foot-and-mouth disease virus transmission dynamics and persistence in a herd of vaccinated dairy cattle in India -
Hayder, S.S., VanderWaal, K., Ranjan, R., Biswal, J.K., Subramaniam, S., Mohapatra, J.K., Sharma, G.K., Rout, M., Dash, B., Das, B., Prusty, B., Sharma, A.K., Stenfeldt, C., Perez, A., Rodriguez, L.L., Arzt, J. 2017. Foot-and-mouth disease virus transmission dynamics and persistence in a herd of vaccinated dairy cattle in India. Transboundary and Emerging Diseases. 65(2):e404-e415. https://doi.org/10.1111/tbed.12774.
Genetic diversity and comparison of diagnostic tests for characterization of foot-and-mouth disease virus strains from Pakistan 2008-2012 -
Ahmed, Z., Pauszek, S.J., Ludi, A., Larocco, M.A., Khan, E., Afzal, M., Arshed, M.J., Farooq, U., Arzt, J., Bertram, M., Brito, B., Naeem, K., Abubakar, M., Rodriguez, L.L. 2017. Genetic diversity and comparison of diagnostic tests for characterization of foot-and-mouth disease virus strains from Pakistan 2008-2012. Transboundary and Emerging Diseases. 65(2):534-546. https://doi.org/10.1111/tbed.12737.
Genome sequences of seven foot-and-mouth disease virus isolates collected from serial samples from one persistently infected carrier cow in Vietnam -
Pauszek, S.J., Bertram, M.R., Vu, L.T., Hartwig, E.J., Smoliga, G.R., Brito, B., Stenfeldt, C., Hung, N.T., Hoang, B.H., Rodriguez, L.L., Dung, D.H., Arzt, J. 2017. Genome sequences of seven foot-and-mouth disease virus isolates collected from serial samples from one persistently infected carrier cow in Vietnam. Genome Announcements. 5:e00849-17. https://doi.org/10.1128/genomeA.00849-17.
Early protection events in swine immunized with an experimental live attenuated classical swine fever marker vaccine, FlagT4G -
Holinka-Patterson, L.G., O'Donnell, V., Risatti, G., Azzinaro, P.A., Arzt, J., Stenfeldt, C., Velazquez-Salinas, L., Gladue, D.P., Borca, M.V. 2017. Early protection events in swine immunized with an experimental live attenuated classical swine fever marker vaccine, FlagT4G. PLoS One. doi: 10.1371/journal.pone.0177433.
Pathogenesis of virulent and attenuated foot and mouth disease virus in cattle -
Arzt, J., Pacheco Tobin, J., Stenfeldt, C., Rodriguez, L.L. 2017. Pathogenesis of virulent and attenuated foot and mouth disease virus in cattle. Virology. 14(1):89. doi: 10.1186/s12985-017-0758-9.
First detection of foot-and-mouth disease virus O/Ind-2001d in Vietnam -
Vu, L.T., Long, N.T., Brito, B., Stenfeldt, C., Phuong, N.T., Hoang, B.H., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, P.P., Quang, L.T., Hung, V.V., Tho, N.D., Dong, P.V., Minh, P.Q., Bertram, M.R., Fish, I.H., Rodriguez, L.L., Dung, D.H., Arzt, J. 2017. First detection of foot-and-mouth disease virus O/Ind-2001d in Vietnam. PLoS One. 12(6):e0177361. https://doi.org/10.1371/journal.pone.0177361.
Proof-of-concept study: profile of circulating micro RNAs in bovine serum harvested during acute and persistent FMDV infection -
Stenfeldt, C., Arzt, J., Smoliga, G., Larocco, M.A., Gutkoska, J., Lawrence, P.J. 2017. Proof-of-concept study: profile of circulating micro RNAs in bovine serum harvested during acute and persistent FMDV infection. Virology Journal. 14:71. doi: 10.1186/s12985-017-0743-3.
Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015 -
Arzt, J., Brito, B.P., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Vu, P.P., Stenfeldt, C., Rodriguez, L.L., Long, N.T., Dung, D.H. 2017. Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015. Genome Announcements. 5(18):e00223-17. doi: 10.1128/genomeA.00223-17.
Phylodynamics of epidemic and asymptomatic foot-and-mouth disease in Vietnam 2010-2014 -
Brito, B., Pauszek, S.J., Eschbaumer, M., Stenfeldt, C., De Carvalho Ferreira, H., Vu, L.T., Phuong, N.T., Hoang, B.H., Tho, N.D., Dong, P.V., Minh, P.Q., Long, N.T., Dung, D.H., Rodriguez, L.L., Arzt, J. 2017. Phylodynamics of epidemic and asymptomatic foot-and-mouth disease in Vietnam 2010-2014. Veterinary Research. 48:24.
Foot-and-mouth disease vaccines -
Diaz-San Segundo, F., Medina, G., Stenfeldt, C., Arzt, J., De Los Santos, T.B. 2016. Foot-and-mouth disease vaccines. Veterinary Microbiology. doi: 10.1016/j.vetmic.2016.12.018.
Quantitative characteristics of the foot-and-mouth disease carrier state under natural conditions in India -
Hayer, S., Ranjan, R., Biswal, J., Mohapatra, J.K., Sharma, G.K., Subramaniam, S., Stenfeldt, C., Perez, A., Rodriguez, L.L., Pattnaik, B., Vanderwaal, K., Arzt, J. 2017. Quantitative characteristics of the foot-and-mouth disease carrier state under natural conditions in India. Transboundary and Emerging Diseases. doi: 10.1111/tbed.12627.
Foot-and-mouth disease virus-associated abortion and vertical transmission following acute infection in cattle under natural conditions -
Ranjan, R., Biswal, J.K., Subramaniam, S., Singh, K.P., Stenfeld, C., Rodriguez, L.L., Pattnaik, B., Arzt, J. 2016. Foot-and-mouth disease virus-associated abortion and vertical transmission following acute infection in cattle under natural conditions. PLoS One. 11(12):e0167163.
Foot-and-mouth disease virus during the incubation period in pigs -
Stenfeldt, C., Pacheco, J., Brito, B.P., Moreno-Torres, K.I., Branan, M.A., Delgado, A., Rodriguez, L.L., Arzt, J. 2016. Foot-and-mouth disease virus during the incubation period in pigs. Frontiers in Veterinary Science. 3:105. doi: 10.3389/fvets.2016.00105.
Site-specific substitution (Q172R) in the VP1 protein of subclinical FMDV isolates collected in Vietnam -
Pauszek, S.J., Eschbaumer, M., Brito, B., Ferreira De Carvalho, H.C., Vu, L.T., Phuong, N.T., Hoang, B.H., Tho, N.D., Tung, N., Thuy, N.T., Long, N.T., Dung, D.H., Rodriguez, L.L., Arzt, J. 2016. Site-specific substitution (Q172R) in the VP1 protein of subclinical FMDV isolates collected in Vietnam. Virology Reports. 6:90-96.
Systemic immune response and virus persistence after foot-and-mouth disease virus infection of naïve cattle and cattle vaccinated with a homologous adenovirus-vectored vaccine -
Eschbaumer, M., Stenfeldt, C., Rekant, S.I., Pacheco Tobin, J., Hartwig, E.J., Smoliga, G.R., Kenney, M.A., Golde, W.T., Rodriguez, L.L., Arzt, J. 2016. Systemic immune response and virus persistence after foot-and-mouth disease virus infection of naïve cattle and cattle vaccinated with a homologous adenovirus-vectored vaccine. BioMed Central (BMC) Veterinary Research. 12:205.
Transcriptomic analysis of persistent infection with foot-and-mouth disease virus in cattle suggests impairment of cell-mediated immunity in the nasopharynx -
Eschbaumer, M., Stenfeldt, C., Smoliga, G.R., Pacheco, J., Rodriguez, L.L., Li, R.W., Zhu, J.J., Arzt, J. 2016. Transcriptomic analysis of persistent infection with foot-and-mouth disease virus in cattle suggests impairment of cell-mediated immunity in the nasopharynx. PLoS One. 11:e0162750.
Infection dynamics of foot-and-mouth disease virus in cattle following intra-nasopharyngeal inoculation or contact exposure -
Pacheco, J., Stenfeldt, C., Rodriguez, L.L., Arzt, J. 2016. Infection dynamics of foot-and-mouth disease virus in cattle following intra-nasopharyngeal inoculation or contact exposure. Journal of Comparative Pathology. 155(4):314-325. doi: 10.1016/j.jcpa.2016.08.005.
Selective factors associated with the evolution of codon usage in natural populations of arboviruses and their practical application to infer possible hosts for emerging viruses -
Velazquez-Salinas, L., Zarate, S., Eschbaumer, M., Lobo, F.P., Gladue, D.P., Arzt, J., Novella, I.S., Rodriguez, L.L. 2016. Selective factors associated with the evolution of codon usage in natural populations of arboviruses and their practical application to infer possible hosts for emerging viruses. PLoS One. PLoS ONE 11(7): e0159943. doi:10.1371/journal.pone.0159943.
The pathogenesis of Foot-and-Mouth Disease in pigs -
Stenfeldt, C., Diaz-San Segundo, F., De Los Santos, T.B., Rodriguez, L.L., Arzt, J. 2016. The pathogenesis of Foot-and-Mouth Disease in pigs. Frontiers in Veterinary Science. 3:41. doi: 10.3389/fvets.2016.00041.
The foot-and-mouth disease carrier state divergence in cattle -
Stenfeldt, C., Eschbaumer, M., Rekant, S.I., Pacheco, J.M., Smoliga, G.R., Hartwig, E.J., Rodriguez, L.L., Arzt, J. 2016. The foot-and-mouth disease carrier state divergence in cattle. Journal of Virology. doi: 10.1128/JVL00388-16.
Foot-and-Mouth Disease in a small sample of experimentally infected pronghorn (Antilocapra americana) -
Rhyan, J., Mccollum, M., Gidlewski, T., Shalev, M., Ward, G., Donahue, B., Arzt, J., Stenfeldt, C., Mohamed, F., Nol, P., Deng, M., Metwally, S., Mckenna, T., Salman, M. 2016. Foot-and-Mouth Disease in a small sample of experimentally infected pronghorn (Antilocapra americana). Journal of Wildlife Diseases. 52(4):862-873.
Pathogenesis and micro-anatomic characterization of a cell-adapted mutant foot-and-mouth disease virus in cattle: impact of the Jumonji C-domain containing protein 6 (JMJD6) and route of innoculation -
Lawrence, P.J., Pacheco Tobin, J., Stenfeldt, C., Arzt, J., Rai, D., Rieder, A.E. 2016. Pathogenesis and micro-anatomic characterization of a cell-adapted mutant foot-and-mouth disease virus in cattle: impact of the Jumonji C-domain containing protein 6 (JMJD6) and route of innoculation. Journal of Virology. 492:108-117. doi: 10.1016/j.virol.2016.02.004.
Evaluation of infectivity, virulence and transmission of FDMV field strains of serotypes O and A isolated in 2010 from outbreaks in the Republic of Korea -
Pacheco Tobin, J., Lee, K., Bishop, E.A., Hartwig, E.J., Pauszek, S.J., Smoliga, G.R., Kim, S., Park, J., Ko, Y., Lee, H., Dongseob, T., Cho, I., Kim, B., Rodriguez, L.L., Arzt, J. 2016. Evaluation of infectivity, virulence and transmission of FDMV field strains of serotypes O and A isolated in 2010 from outbreaks in the Republic of Korea. PLoS One. 11(1): e0146445. doi: 10.1371/journal.pone.0146445.
Pathogenesis of primary foot-and-mouth disease virus infection in the nasopharynx of vaccinated and non-vaccinated cattle -
Stenfeldt, C., Eschbaumer, M., Rekant, S.I., Pacheco Tobin, J., Rodriguez, L.L., Arzt, J. 2015. Pathogenesis of primary foot-and-mouth disease virus infection in the nasopharynx of vaccinated and non-vaccinated cattle. PLoS One. 10(11): e0143666. doi: 10.1371/journal.pone.0143666.
An integrative analysis of foot-and-mouth disease virus carriers in Vietnam achieved through targeted surveillance and molecular epidemiology Reprint Icon -
De Carvalho Ferreira, H.C., Pauszek, S.J., Ludi, A., Huston, C.L., Pacheco Tobin, J., Dung, D., Thuy, N., Vu, L., Tho, N., Long, N., Rodriguez, L.L., Arzt, J. 2015. An integrative analysis of foot-and-mouth disease virus carriers in Vietnam achieved through targeted surveillance and molecular epidemiology. Transboundary and Emerging Diseases. doi: 10.1111/tbed.12403.
Effect of storage conditions on subpopulations of peripheral blood T lymphocytes from naive cattle and cattle infected with foot-and-mouth disease virus -
Eschbaumer, M., Stenfeldt, C., Pacheco Tobin, J., Rekant, S.I., Arzt, J. 2016. Effect of storage conditions on subpopulations of peripheral blood T lymphocytes from naive cattle and cattle infected with foot-and-mouth disease virus. Veterinary Clinical Pathology. 45:110-115. https://doi.org/10.1111/vcp.12327.
Early detection of foot-and-mouth disease virus from infected cattle using a dry filter air sampling system Reprint Icon -
Pacheco Tobin, J., Brito, B., Hartwig, E.J., Smoliga, G.R., Perez, A., Arzt, J., Rodriguez, L.L. 2015. Early detection of foot-and-mouth disease virus from infected cattle using a dry filter air sampling system. Transboundary and Emerging Diseases. doi: 10.1111/tbed.12404.
Deletion of African swine fever virus Georgia 2007 virulence-associated gene 9GL (B119L) leads to virus attenuation in swine at low doses while inducing an effective protection against homologous challenge -
O'Donnell, V., Holinka-Patterson, L.G., Krug, P.W., Gladue, D.P., Carlson, J., Sanford, B.J., Alfano, M., Kramer, E., Lu, Z., Arzt, J., Reese, B., Carrillo, C., Risatti, G., Borca, M.V. 2015. Deletion of African swine fever virus Georgia 2007 virulence-associated gene 9GL (B119L) leads to virus attenuation in swine at low doses while inducing an effective protection against homologous challenge. Journal of Virology. 89(16):8556-8566. DOI: 10.1128/JVI.00969-15.
Veterinary applications of infrared thermography -
Rekant, S., Lyons, M., Pacheco Tobin, J., Arzt, J., Rodriguez, L.L. 2016. Veterinary applications of infrared thermography. American Journal of Veterinary Research. 77:98-107. https://doi.org/10.2460/ajvr.77.1.98.
Clinical and virological dynamics of a serotype O 2010 South East Asia lineage foot-and-mouth disease virus in sheep using natural and simulated natural inoculation and exposure systems Reprint Icon -
Stenfeldt, C., Pacheco Tobin, J., Singanallur, N.B., De Carvalho Ferreira, H.C., Howey, E.B., Vosloo, W., Rodriguez, L.L., Arzt, J. 2015. Clinical and virological dynamics of a serotype O 2010 South East Asia lineage foot-and-mouth disease virus in sheep using natural and simulated natural inoculation and exposure systems. Veterinary Microbiology. DOI:10.1016/j.vetmic.2015.04.004.
Persistent foot-and-mouth disease virus infection in the nasopharynx of cattle: tissue-specific distribution and local cytokine expression -
Pacheco Tobin, J., Smoliga, G.R., O'Donnell, V., Brito-Rodriguez, B., Stenfeldt, C., Rodriguez, L.L., Arzt, J. 2015. Persistent foot-and-mouth disease virus infection in the nasopharynx of cattle: tissue-specific distribution and local cytokine expression. Virology. DOI:10.1371/journal.pone.0125698.
African swine fever virus Georgia isolate harboring deletions of MGF360 and MGF505 genes is attenuated in swine and confers protection against challenge with the virulent parental virus Reprint Icon -
O'Donnell, V., Holinka-Patterson, L.G., Gladue, D.P., Sanford, B.J., Krug, P.W., Lu, Z., Arzt, J., Reese, B., Carrillo, C., Risatti, G.R., Borca, M.V. 2015. African swine fever virus Georgia isolate harboring deletions of MGF360 and MGF505 genes is attenuated in swine and confers protection against challenge with the virulent parental virus. Journal of Virology. 89(11):6048-6056.
Progressive adaptation of a Georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major changes of the viral genome Reprint Icon -
Krug, P.W., Holinka-Patterson, L.G., O'Donnell, V., Reese, B., Sanford, B.J., Fernandez-Sainz, I., Gladue, D.P., Arzt, J., Rodriguez, L.L., Risatti, G.R., Borca, M.V. 2014. Progressive adaptation of a Georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major changes of the viral genome. Journal of Virology. 89(4):2324-2332.
Early events in the pathogenesis of foot-and-mouth disease in pigs; identification of oropharyngeal tonsils as sites of primary and sustained viral replication -
Stenfeldt, C., Pacheco Tobin, J., Rodriguez, L.L., Arzt, J. 2014. Early events in the pathogenesis of foot-and-mouth disease in pigs; identification of oropharyngeal tonsils as sites of primary and sustained viral replication. PLoS One. DOI:10.1371/journal.pone.0106859.
Morphologic and phenotypic characteristics of myocarditis in two pigs infected by foot-and mouth disease virus strains of serotypes O or A -
Stenfeldt, C., Pacheco Tobin, J., Borca, M.V., Rodriguez, L.L., Arzt, J. 2014. Morphologic and phenotypic characteristics of myocarditis in two pigs infected by foot-and mouth disease virus strains of serotypes O or A. Acta Veterinaria Scandinavica. 56(1):42.
Detection of Foot-and-Mouth Disease Virus RNA and capsid protein in lymphoid tissues of convalescent pigs does not indicate existence of a carrier state -
Stenfeldt, C., Pacheco Tobin, J., Smoliga, G.R., Bishop, E.A., Pauszek, S.J., Hartwig, E.J., Rodriguez, L.L., Arzt, J. 2014. Detection of Foot-and-Mouth Disease Virus RNA and capsid protein in lymphoid tissues of convalescent pigs does not indicate existence of a carrier state. Transboundary and Emerging Diseases. DOI: 10.1111/tbed.12235.
Infection dynamics of foot-and-mouth disease virus in pigs using two novel simulated natural inoculation methods Reprint Icon -
Stenfeldt, C., Pacheco Tobin, J., Rodriguez, L.L., Arzt, J. 2014. Infection dynamics of foot-and-mouth disease virus in pigs using two novel simulated natural inoculation methods. Research in Veterinary Science. 96:396-405.
Serotype diversity of foot-and-mouth-disease virus in livestock without history of vaccination in the far north region of Cameroon -
Ludi, A., Ahmed, Z., Pomeroy, L.W., Pauszek, S.J., Smoliga, G.R., Moritz, M., Dickmu, S., Abdoulkadiri, S., Arzt, J., Garabed, R., Rodriguez, L.L. 2014. Serotype diversity of foot-and-mouth-disease virus in livestock without history of vaccination in the far north region of Cameroon. Transboundary and Emerging Diseases. 63:e27-38. doi: 10.1111/TBED.12227.
Foot and mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection Reprint Icon -
Arzt, J., Pacheco Tobin, J., Tucker, M.T., Smoliga, G.R., Bishop, E.A., Pauszek, S.J., Hartwig, E.J., De Los Santos, T.B., Rodriguez, L.L. 2014. Foot and mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection. Virology. 452-453:12-22.
Interaction of foot-and-mouth disease virus non-structural protein 3A with host protein DCTN3 is important for viral virulence in cattle -
Gladue, D.P., O'Donnell, V., Baker-Branstetter, R., Pacheco Tobin, J., Holinka-Patterson, L.G., Arzt, J., Pauszek, S.J., Fernandez-Sainz, I., Fletcher, P., Brocchi, E., Lu, Z., Rodriguez, L.L., Borca, M.V. 2014. Interaction of foot-and-mouth disease virus non-structural protein 3A with host protein DCTN3 is important for viral virulence in cattle. Journal of Virology. 88(5):2737-2747.
The pathogenesis of highly virulent African Swine Fever virus in domestic pigs exposed via intraoropharyngeal, intranasopharyngeal, and intramuscular inoculation, and by direct contact with infected pigs Reprint Icon -
Howey, E.B., O'Donnell, V., De Carvalho Ferreira, H.C., Borca, M.V., Arzt, J. 2013. The pathogenesis of highly virulent African Swine Fever virus in domestic pigs exposed via intraoropharyngeal, intranasopharyngeal, and intramuscular inoculation, and by direct contact with infected pigs. Virus Research. 178(2):328-339.
Characterization of a chimeric foot-and-mouth disease virus bearing bovine rhinitis B virus leader proteinase Reprint Icon -
Uddowla, S., Pacheco Tobin, J., Larson, C., Bishop, E.A., Rodriguez, L.L., Rai, D., Arzt, J., Rieder, A.E. 2013. Characterization of a chimeric foot-and-mouth disease virus bearing bovine rhinitis B virus leader proteinase. Virology. 447(1-2):172-180.
A partial deletion in non-structural protein 3A can attenuate foot-and-mouth disease virus in cattle Reprint Icon -
Pacheco Tobin, J., Gladue, D.P., Holinka-Patterson, L.G., Arzt, J., Bishop, E.A., Smoliga, G.R., Pauszek, S.J., Bracht, A.J., O'Donnell, V., Fernandez-Sainz, I., Fletcher, P., Piccone, M.E., Rodriguez, L.L., Borca, M.V. 2013. A partial deletion in non-structural protein 3A can attenuate foot-and-mouth disease virus in cattle. Virology. 446(1-2):260-267.
Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression Reprint Icon -
Zhu, J.J., Arzt, J., Puckette, M.C., Smoliga, G.R., Pacheco Tobin, J., Rodriguez, L.L. 2013. Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression. PLoS One. 8(5):e64119. DOI:10.1371/journal.pone.0064119.
Early adaptive immune responses in the respiratory tract of foot and mouth disease-infected cattle Reprint Icon -
Pega, J., Bucafusco, D., Di Giacomo, S., Malacari, D., Capozzo, A., Arzt, J., Perez-Beascoechea, C., Maradei, E., Rodriguez, L.L., Borca, M.V., Perez-Filgueira, M. 2012. Early adaptive immune responses in the respiratory tract of foot and mouth disease-infected cattle. Journal of Virology. 87(5):2489-2495.
Time-dependent biodistribution and transgene expression of a recombinant human adenovirus serotype 5-luciferase vector as a surrogate agent for rAd5-FMDV vaccines in cattle Reprint Icon -
Montiel, N.A., Smoliga, G.R., Arzt, J. 2012. Time-dependent biodistribution and transgene expression of a recombinant human adenovirus serotype 5-luciferase vector as a surrogate agent for rAd5-FMDV vaccines in cattle. Veterinary Immunology and Immunopathology. 151(1-2):37-48. DOI: 110.1016/j.vetimm.2012.10.003.
The early pathogenesis of foot-and-mouth disease -
Arzt, J., Rodriguez, L.L. 2013. The early pathogenesis of foot-and-mouth disease. In: Tipics in Foot and Mouth Disease. Scientific Developments and Technical Challenges in the Progressive Control of Foot-and-Mouth Disease in South Asia, February 13-15, 2012, New Delhi, India. p. 24-36.
Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle Reprint Icon -
Perez-Martin, E., Weiss, M., Diaz San Segundo, F.C., Pacheco Tobin, J., Arzt, J., Grubman, M.J., De Los Santos, T.B. 2012. Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle. Journal of Virology. 86(8):4477-4487.
Foot-and-mouth disease: global status and Indian perspective Reprint Icon -
Biswal, J.K., Sanyal, A., Rodriguez, L.L., Subramaniam, S., Arzt, J., Sharma, G.K., Hammond, J.M., Parida, S., Mohapatra, J.K., Mathapati, B.S., Dash, B.B., Ranjan, R., Rout, M., Venketaramanan, R., Misri, J., Krishna, L., Prasad, G., Pathak, K.M., Pattnaik, B. 2012. Foot-and-mouth disease: global status and Indian perspective. Indian Journal of Animal Sciences. 82(2):109-131.
Direct contact transmission of three different foot-and-mouth disease virus strains in swine demonstrates important strain-specific differences -
Pacheco Tobin, J., Tucker, M.T., Hartwig, E.J., Bishop, E.A., Arzt, J., Rodriguez, L.L. 2012. Direct contact transmission of three different foot-and-mouth disease virus strains in swine demonstrates important strain-specific differences. The Veterinary Journal. 193(2):456-463.
Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues Reprint Icon -
Montiel, N., Smoliga, G.R., Arzt, J. 2012. Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues. Vaccine. 30(9):1690-1701.
The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions -
Arzt, J., Baxt, B., Grubman, M.J., Jackson, T., Juleff, N., Rhyan, J., Rieder, A.E., Waters, R., Rodriguez, L.L. 2011. The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions. Transboundary and Emerging Diseases. 58(4):305-326.
The pathogenesis of foot-and-mouth disease I; viral pathways in cattle -
Arzt, J., Juleff, N., Zhang, Z., Rodriguez, L.L. 2011. The pathogenesis of foot-and-mouth disease I; viral pathways in cattle. Transboundary and Emerging Diseases. 58(4):291-304.
The early pathogenesis of foot-and-mouth disease in cattle after aerosol inoculation -
Arzt, J. 2010. The early pathogenesis of foot-and-mouth disease in cattle after aerosol inoculation [Ph.D. Dissertation]. Ft. Collins, CO: Colorado State University: The Graduate School at Colorado State University. 155 p.
The early pathogenesis of foot-and-mouth disease in cattle after aerosol innoculation: identification of the nasopharynx as the primary site of infection -
Arzt, J., Pacheco Tobin, J., Rodriguez, L.L. 2010. The early pathogenesis of foot-and-mouth disease in cattle after aerosol innoculation: identification of the nasopharynx as the primary site of infection. Veterinary Pathology. 47(6):1048-1063.
Agricultural diseases on the move early in the third millennium -
Arzt, J., White, W.R., Thomsen, B.V., Brown, C.C. 2010. Agricultural diseases on the move early in the third millennium. Veterinary Pathology. 47(1):15-27.
Optimization of immunohistochemical and fluorescent antibody techniques for localization of foot-and-mouth disease virus in animal tissues -
Arzt, J., Gregg, D.A., Clavijo, A., Rodriguez, L.L. 2009. Optimization of immunohistochemical and fluorescent antibody techniques for localization of foot-and-mouth disease virus in animal tissues. Journal of Veterinary Diagnostic Investigation. 21(6):779-792.
Early Events in the Pathogenesis of Foot-and-Mouth Disease in Cattle After Controlled Aerosol Exposure -
Pacheco Tobin, J., Arzt, J., Rodriguez, L.L. 2008. Early Events in the Pathogenesis of Foot-and-Mouth Disease in Cattle After Controlled Aerosol Exposure. The Veterinary Journal. 183(1):46-53.
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