Location: Foreign Animal Disease ResearchTitle: Novel recombinant foot-and-mouth disease virus circulating in Vietnam
|BRITO, BARBARA - University Of Technology Sydney|
|PALINSKI, RACHEL - University Of Kansas|
|FISH, IAN - Oak Ridge Institute For Science And Education (ORISE)|
|PAUSZEK, STEVEN - Animal And Plant Health Inspection Service (APHIS)|
|VU, LE - Dept Of Animal Health, Vietnam|
|DUNG, DO - Dept Of Animal Health, Vietnam|
|HOANG, BUI - Dept Of Animal Health, Vietnam|
|PHUONG, NGUYEN - Dept Of Animal Health, Vietnam|
|VU, PHAM - Dept Of Animal Health, Vietnam|
|DUNG, NGUYEN - Dept Of Animal Health, Vietnam|
|TIEN, NGUYEN - Dept Of Animal Health, Vietnam|
|DONG, PHAM - Dept Of Animal Health, Vietnam|
Submitted to: Microbiology Resource Announcements
Publication Type: Other
Publication Acceptance Date: 11/27/2020
Publication Date: 1/7/2021
Citation: Bertram, M.R., Brito, B., Palinski, R., Fish, I., Pauszek, S., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Dung, D.H., Arzt, J., Hoang, B.H., Phuong, N.T., Vu, P.P., Dung, N.K., Tien, N.N., Dong, P.V. 2021. Novel recombinant foot-and-mouth disease virus circulating in Vietnam. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.01263-20.
Interpretive Summary: Foot-and-mouth disease virus (FMDV) is an important viral disease affecting animal health and economics through impacts on agriculture and trade. There are numerous different strains of FMDV, and vaccination or previous infection with one strain does not protect against infection with a different strain, so it is important to monitor which strains are causing outbreaks in an area. Additionally, recombination between different strains can create new strains that may be more likely to cause an outbreak. We report the genomes of a recombinant strain from Vietnam and emphasize the importance of sequencing the full genome in order to detect recombinant strains.
Technical Abstract: We report the genomes of 12 recombinant foot-and-mouth disease virus isolates from Vietnam. The recombinant strain has a capsid region from an A/Sea-97 strain, and non-structural segment from an O/ME-SA/PanAsia strain. The isolates were obtained from two outbreak samples collected in June 2017 and 10 subclinical samples collected 2017 – 2019.