Foot-and-mouth disease virus serotype O/CATHAY near full-length genomes from 5 outbreaks in Vietnam, 2017-2019

Authors: VIERRA, DAVID - Kansas State University; BERTMAN, MIRANDA - Oak Ridge Institute For Science And Education (ORISE); Palinski, Rachel; Pauszek, Steven; Hartwig, Ethan; Smoliga, George; LE, VU - Ministry Of Agriculture And Rural Development (MARD); BUI, HOANG - Ministry Of Agriculture And Rural Development (MARD); NGUYEN, PHUONG - Ministry Of Agriculture And Rural Development (MARD); PHAM, DONG - Ministry Of Agriculture And Rural Development (MARD); NGUYEN, TIEN - Ministry Of Agriculture And Rural Development (MARD); DO, DUNG - Ministry Of Agriculture And Rural Development (MARD); Arzt, Jonathan

Submitted to: Microbiology Resource Announcements
Publication Type: Database / Dataset
Publication Acceptance Date: 1/8/2020
Publication Date: 1/30/2020
Citation: Vierra, D., Bertman, M., Palinski, R.M., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Le, V.T., Bui, H.H., Nguyen, P.T., Pham, D.V., Nguyen, T.N., Do, D.H., Arzt, J. 2020. Foot-and-mouth disease virus serotype O/CATHAY near full-length genomes from 5 outbreaks in Vietnam, 2017-2019. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.01315-19.
DOI: https://doi.org/10.1128/MRA.01315-19

Interpretive Summary: Foot-and-mouth disease virus (FMDV) is one of the most economically impactful infectious diseases of livestock, with substantial effects on agriculture and trade. The impacts of this disease on food security are prominent throughout Southeast Asia. The USA is free of FMDV, but outbreaks here would lead to destruction large amounts of livestock resulting in huge economic losses, estimated in billions of dollars. So, it is of critical importance to be aware of new strains of FMDV when they emerge to ensure preparedness in the US homeland. This paper provides full genetic data for 5 FMDV outbreak viruses from Vietnam between 2017-2019. This will contribute not only to the understanding of the virus’ spread and evolution within Vietnam but in preparedness for responders in the USA.

Technical Abstract: We report near-complete genomes for 5 foot-and-mouth disease viruses (FMDV) from distinct provinces in Vietnam. All 5 viruses grouped within the O/CATHAY topotype. Sequences contain the full polyprotein coding sequence and partial UTRs. These genomes provide critical data on the spread and evolution of FMDV in the region.