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ARS Home » Northeast Area » Orient Point, New York » Plum Island Animal Disease Center » Foreign Animal Disease Research » People & Locations » George Smoliga

George R Smoliga
Foreign Animal Disease Research
Microbiologist

Phone: (631) 323-3062
Fax: (631) 323-3006

40550 ROUTE 25 ORIENT POINT WAREHOUSE
ORIENT POINT, NY 11957

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Duration of Contagion of FMDV in Infected Live Pigs and Carcasses Reprint Icon - (Peer Reviewed Journal)
Stenfeldt, C., Bertram, M., Smoliga, G.R., Hartwig, E.J., Delgado, A., Arzt, J. 2020. Duration of Contagion of FMDV in Infected Live Pigs and Carcasses. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2020.00334.
Foot-and-mouth disease virus serotype A complete genome sequence from Kenya in 2016 ()
First report of near-complete genome sequences of foot-and-mouth disease virus serotype O strains from Kenya Reprint Icon ()
Palinski, R.M., Sangula, A., Bertram, M.R., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Obanda, V., Omondi, G., Vanderwaal, K., Arzt, J. 2019. First Report of Near-Complete Genome Sequences of Footand- Mouth Disease Virus Serotype O Strains from Kenya. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.00808-19.
First report of near-complete genome sequences of foot-and-mouth disease virus serotype O strains from Kenya Reprint Icon ()
Fish, I., Vierra, D., Ehzibolo, D., Palinski, R.M., Bertram, M., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Arzt, J. 2019. First report of near-complete genome sequences of foot-and-mouth disease virus serotype O strains from Kenya. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.00808-19.
Genome sequences of 18 foot-and-mouth disease virus outbreak strains of serotype O sublineage Ind2001d from India 2013-2014 Reprint Icon ()
Bertman, M.R., Palinski, R.M., Ranjan, R., Biswal, J.K., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vierra, D., Fish, I.H., Subramaniam, S., Mohapatra, J.K., Das, B., Pattnaik, B., Arzt, J. 2019. Genome sequences of 18 foot-and-mouth disease virus outbreak strains of serotype O sublineage Ind2001d from India 2013-2014. Microbiology Resource Announcements. http://www.doi.org/10.1128/MRA.00776-19.
First genome sequence of Foot-and-mouth disease virus serotype O sublineage Ind2001e from Vietnam Reprint Icon - (Peer Reviewed Journal)
Palinski, R., Bertram, M.R., Vu, L.T., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Stenfeldt, C., Fish, I.H., Hoang, B.H., Dung, D.H., Arzt, J. 2019. First genome sequence of Foot-and-mouth disease virus serotype O sublineage Ind2001e from Vietnam. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.01424-18.
First detection of Senecavirus A in Vietnam Reprint Icon - (Peer Reviewed Journal)
Arzt, J., Bertram, M.R., Vu, L.T., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Palinski, R., Stenfeldt, C., Fish, I.H., Hoang, B.H., Dung, D.H. 2019. First detection of Senecavirus A in Vietnam. Emerging Infectious Diseases. https://doi.org/10.1128/MRA.01247-18.
Contact challenge of cattle with foot-and-mouth disease virus validates the role of the nasopharyngeal epithelium as the site of primary and persistent infection. Reprint Icon - (Peer Reviewed Journal)
Stenfeldt, C., Smoliga, G.R., Hartwig, E.J., Palinski, R., Fish, I.H., Silva, E.B., Pauszek, S.J., Arzt, J. 2018. Contact challenge of cattle with foot-and-mouth disease virus validates the role of the nasopharyngeal epithelium as the site of primary and persistent infection. Scientific Reports. https://doi.org/10.1128/mSphere.00493-18.
Lack of transmission of foot-and-mouth disease virus from persistently infected cattle to naïve cattle under field conditions in Vietnam Reprint Icon - (Peer Reviewed Journal)
Bertram, M.R., Vu, L.T., Pauszek, S.J., Brito, B.P., Hartwig, E.J., Smoliga, G.R., Hoang, B.H., Phuong, N.T., Stenfeldt, C., Fish, I.H., Hung, V.V., Delgado, A., VanderWaal, K., Rodriguez, L.L., Long, N.T., Dung, D.H., Arzt, J. 2018. Lack of transmission of foot-and-mouth disease virus from persistently infected cattle to naïve cattle under field conditions in Vietnam. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2018.00174.
A traditional evolutionary history of foot-and-mouth disease viruses in Southeast Asia challenged by analyses of non-structural protein coding sequences Reprint Icon - (Peer Reviewed Journal)
Brito, B.P., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Vu, P.P., Stenfeldt, C., Rodriguez, L.L., King, D.P., Knowles, N.J., Bachanek-Bankowska, K., Long, N.T., Dung, D.H., Arzt, J. 2018. A traditional evolutionary history of foot-and-mouth disease viruses in Southeast Asia challenged by analyses of non-structural protein coding sequences. Scientific Reports. 8:6472. https://doi.org/10.1038/s41598-018-24870-6.
Effect of vaccination on cattle herds previously exposed to foot and mouth disease in Cameroon Reprint Icon - (Peer Reviewed Journal)
Bertram, M.R., Delgado, A., Pauszek, S.J., Smoliga, G.R., Brito, B.P., Stenfeldt, C., Hartwig, E.J., Dickmu-Jumbo, S., Abdoulmoumini, M., Abona Olivia, A., Salhine, R., Rodriguez, L.L., Gerabed, R., Arzt, J. 2018. Effect of vaccination on cattle herds previously exposed to foot and mouth disease in Cameroon. Preventive Veterinary Medicine. 155:1-10. https://doi.org/10.1016/j.prevetmed.2018.04.003.
A partial deletion within foot-and-mouth disease virus non-structural protein 3A causes clinical attenuation in cattle but does not prevent subclinical infection Reprint Icon - (Peer Reviewed Journal)
Stenfeldt, C., Arzt, J., Pacheco, J., Gladue, D.P., Smoliga, G.R., Silva, E., Rodriguez, L.L., Borca, M.V. 2018. A partial deletion within foot-and-mouth disease virus non-structural protein 3A causes clinical attenuation in cattle but does not prevent subclinical infection. Virology. 516:115-126. https://doi.org/10.1016/j.virol.2018.01.008.
Clearance of a persistent Picornavirus infection is associated with enhanced pro-apoptotic and cellular immune responses Reprint Icon - (Peer Reviewed Journal)
Stenfeldt, C., Eschbaumer, M., Smoliga, G.R., Rodriguez, L.L., Zhu, J.J., Arzt, J. 2017. Clearance of a persistent Picornavirus infection is associated with enhanced pro-apoptotic and cellular immune responses. Scientific Reports. 7:17800. https://doi.org/10.1038/s41598-017-18112-4.
Genome sequences of seven foot-and-mouth disease virus isolates collected from serial samples from one persistently infected carrier cow in Vietnam - (Peer Reviewed Journal)
Pauszek, S.J., Bertram, M.R., Vu, L.T., Hartwig, E.J., Smoliga, G.R., Brito, B., Stenfeldt, C., Hung, N.T., Hoang, B.H., Rodriguez, L.L., Dung, D.H., Arzt, J. 2017. Genome sequences of seven foot-and-mouth disease virus isolates collected from serial samples from one persistently infected carrier cow in Vietnam. Genome Announcements. 5:e00849-17. https://doi.org/10.1128/genomeA.00849-17.
First detection of foot-and-mouth disease virus O/Ind-2001d in Vietnam - (Peer Reviewed Journal)
Vu, L.T., Long, N.T., Brito, B., Stenfeldt, C., Phuong, N.T., Hoang, B.H., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, P.P., Quang, L.T., Hung, V.V., Tho, N.D., Dong, P.V., Minh, P.Q., Bertram, M.R., Fish, I.H., Rodriguez, L.L., Dung, D.H., Arzt, J. 2017. First detection of foot-and-mouth disease virus O/Ind-2001d in Vietnam. PLoS One. 12(6):e0177361. https://doi.org/10.1371/journal.pone.0177361.
Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015 - (Peer Reviewed Journal)
Arzt, J., Brito, B.P., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Vu, P.P., Stenfeldt, C., Rodriguez, L.L., Long, N.T., Dung, D.H. 2017. Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015. Genome Announcements. 5(18):e00223-17. doi: 10.1128/genomeA.00223-17.
Systemic immune response and virus persistence after foot-and-mouth disease virus infection of naïve cattle and cattle vaccinated with a homologous adenovirus-vectored vaccine - (Peer Reviewed Journal)
Eschbaumer, M., Stenfeldt, C., Rekant, S.I., Pacheco Tobin, J., Hartwig, E.J., Smoliga, G.R., Kenney, M.A., Golde, W.T., Rodriguez, L.L., Arzt, J. 2016. Systemic immune response and virus persistence after foot-and-mouth disease virus infection of naïve cattle and cattle vaccinated with a homologous adenovirus-vectored vaccine. BioMed Central (BMC) Veterinary Research. 12:205.
Transcriptomic analysis of persistent infection with foot-and-mouth disease virus in cattle suggests impairment of cell-mediated immunity in the nasopharynx - (Peer Reviewed Journal)
Eschbaumer, M., Stenfeldt, C., Smoliga, G.R., Pacheco, J., Rodriguez, L.L., Li, R.W., Zhu, J.J., Arzt, J. 2016. Transcriptomic analysis of persistent infection with foot-and-mouth disease virus in cattle suggests impairment of cell-mediated immunity in the nasopharynx. PLoS One. 11:e0162750.
The foot-and-mouth disease carrier state divergence in cattle - (Peer Reviewed Journal)
Stenfeldt, C., Eschbaumer, M., Rekant, S.I., Pacheco, J.M., Smoliga, G.R., Hartwig, E.J., Rodriguez, L.L., Arzt, J. 2016. The foot-and-mouth disease carrier state divergence in cattle. Journal of Virology. doi: 10.1128/JVL00388-16.
Evaluation of infectivity, virulence and transmission of FDMV field strains of serotypes O and A isolated in 2010 from outbreaks in the Republic of Korea - (Peer Reviewed Journal)
Pacheco Tobin, J., Lee, K., Bishop, E.A., Hartwig, E.J., Pauszek, S.J., Smoliga, G.R., Kim, S., Park, J., Ko, Y., Lee, H., Dongseob, T., Cho, I., Kim, B., Rodriguez, L.L., Arzt, J. 2016. Evaluation of infectivity, virulence and transmission of FDMV field strains of serotypes O and A isolated in 2010 from outbreaks in the Republic of Korea. PLoS One. 11(1): e0146445. doi: 10.1371/journal.pone.0146445.
Early detection of foot-and-mouth disease virus from infected cattle using a dry filter air sampling system Reprint Icon - (Peer Reviewed Journal)
Pacheco Tobin, J., Brito, B., Hartwig, E.J., Smoliga, G.R., Perez, A., Arzt, J., Rodriguez, L.L. 2015. Early detection of foot-and-mouth disease virus from infected cattle using a dry filter air sampling system. Transboundary and Emerging Diseases. doi: 10.1111/tbed.12404.
Persistent foot-and-mouth disease virus infection in the nasopharynx of cattle: tissue-specific distribution and local cytokine expression - (Peer Reviewed Journal)
Pacheco Tobin, J., Smoliga, G.R., O'Donnell, V., Brito-Rodriguez, B., Stenfeldt, C., Rodriguez, L.L., Arzt, J. 2015. Persistent foot-and-mouth disease virus infection in the nasopharynx of cattle: tissue-specific distribution and local cytokine expression. Virology. DOI:10.1371/journal.pone.0125698.
Virus-host interactions in persistently FMDV-infected cells derived from bovine pharynx - (Peer Reviewed Journal)
O'Donnell, V., Pacheco Tobin, J., Larocco, M.A., Gladue, D.P., Pauszek, S.J., Smoliga, G.R., Krug, P.W., Baxt, B., Borca, M.V., Rodriguez, L.L. 2014. Virus-host interactions in persistently FMDV-infected cells derived from bovine pharynx. Virology. 468-470C:185-196.
Detection of Foot-and-Mouth Disease Virus RNA and capsid protein in lymphoid tissues of convalescent pigs does not indicate existence of a carrier state - (Peer Reviewed Journal)
Stenfeldt, C., Pacheco Tobin, J., Smoliga, G.R., Bishop, E.A., Pauszek, S.J., Hartwig, E.J., Rodriguez, L.L., Arzt, J. 2014. Detection of Foot-and-Mouth Disease Virus RNA and capsid protein in lymphoid tissues of convalescent pigs does not indicate existence of a carrier state. Transboundary and Emerging Diseases. DOI: 10.1111/tbed.12235.
Serotype diversity of foot-and-mouth-disease virus in livestock without history of vaccination in the far north region of Cameroon - (Peer Reviewed Journal)
Ludi, A., Ahmed, Z., Pomeroy, L.W., Pauszek, S.J., Smoliga, G.R., Moritz, M., Dickmu, S., Abdoulkadiri, S., Arzt, J., Garabed, R., Rodriguez, L.L. 2014. Serotype diversity of foot-and-mouth-disease virus in livestock without history of vaccination in the far north region of Cameroon. Transboundary and Emerging Diseases. 63:e27-38. doi: 10.1111/TBED.12227.
Foot and mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection Reprint Icon - (Peer Reviewed Journal)
Arzt, J., Pacheco Tobin, J., Tucker, M.T., Smoliga, G.R., Bishop, E.A., Pauszek, S.J., Hartwig, E.J., De Los Santos, T.B., Rodriguez, L.L. 2014. Foot and mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection. Virology. 452-453:12-22.
A partial deletion in non-structural protein 3A can attenuate foot-and-mouth disease virus in cattle Reprint Icon - (Peer Reviewed Journal)
Pacheco Tobin, J., Gladue, D.P., Holinka-Patterson, L.G., Arzt, J., Bishop, E.A., Smoliga, G.R., Pauszek, S.J., Bracht, A.J., O'Donnell, V., Fernandez-Sainz, I., Fletcher, P., Piccone, M.E., Rodriguez, L.L., Borca, M.V. 2013. A partial deletion in non-structural protein 3A can attenuate foot-and-mouth disease virus in cattle. Virology. 446(1-2):260-267.
Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression Reprint Icon - (Peer Reviewed Journal)
Zhu, J.J., Arzt, J., Puckette, M.C., Smoliga, G.R., Pacheco Tobin, J., Rodriguez, L.L. 2013. Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression. PLoS One. 8(5):e64119. DOI:10.1371/journal.pone.0064119.
Time-dependent biodistribution and transgene expression of a recombinant human adenovirus serotype 5-luciferase vector as a surrogate agent for rAd5-FMDV vaccines in cattle Reprint Icon - (Peer Reviewed Journal)
Montiel, N.A., Smoliga, G.R., Arzt, J. 2012. Time-dependent biodistribution and transgene expression of a recombinant human adenovirus serotype 5-luciferase vector as a surrogate agent for rAd5-FMDV vaccines in cattle. Veterinary Immunology and Immunopathology. 151(1-2):37-48. DOI: 110.1016/j.vetimm.2012.10.003.
Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues Reprint Icon - (Peer Reviewed Journal)
Montiel, N., Smoliga, G.R., Arzt, J. 2012. Early detection and visualization of human adenovirus serotype 5-viral vectors carrying foot-and-mouth disease virus or luciferase transgenes in cell lines and bovine tissues. Vaccine. 30(9):1690-1701.
Specific detection of rinderpest virus by real-time reverse transcription-PCR in preclincal and clinical samples of experimentally infected cattle - (Peer Reviewed Journal)
Carrillo, C., Prarat, M.V., Vagnozzi, A., Calahan, J.D., Smoliga, G.R., Nelson, W.D., Rodriguez, L.L. 2010. Specific detection of rinderpest virus by real-time reverse transcription-PCR in preclincal and clinical samples of experimentally infected cattle. Journal of Clinical Microbiology. 11:4094-4101.
Domestic cattle as a non-conventional amplifying host of vesicular stomatitis New Jersey virus - (Peer Reviewed Journal)
Smith, P.F., Howerth, E.W., Carter, D., Gray, E.W., Noblet, R., Smoliga, G.R., Rodriguez, L.L., Mead, D.G. 2010. Domestic cattle as a non-conventional amplifying host of vesicular stomatitis New Jersey virus. Medical and Veterinary Entomology. Available:[doi:10.1111/j.1365-2915.2010.00932.x].
Lesion development and replication kinetics during early infection in cattle inoculated with vesicular stomatitis New Jersey virus via scarification and black fly (Simulium vittatum) bite - (Peer Reviewed Journal)
Reis, J.L., Rodriguez, L.L., Mead, D.G., Smoliga, G.R., Brown, C.C. 2011. Lesion development and replication kinetics during early infection in cattle inoculated with vesicular stomatitis New Jersey virus via scarification and black fly (Simulium vittatum) bite. Veterinary Pathology. 48(3):547-557.
Cytokine mRNA expression in foot-and-mouth disease virus (FMDV) persistently infected bovine pharynx cultures: effect of IFNgamma on replication of persistent virus - (Abstract Only)
O'Donnell, V., Smoliga, G.R., Pacheco Tobin, J., Baxt, B., Rodriguez, L.L. 2009. Cytokine mRNA expression in foot-and-mouth disease virus (FMDV) persistently infected bovine pharynx cultures: effect of IFNgamma on replication of persistent virus. American Society for Virology Meeting. Paper No. W36-9: P. 178.
Experimental Transmission of Vesicular Stomatitis New Jersey Virus From Black Flies (Simulium vittatum) To Cattle: Clinical Outcome Is Determined By Site of Insect Feeding - (Peer Reviewed Journal)
Mead, D.G., Lovett, K.R., Murphy, M.D., Pauszek, S.J., Smoliga, G.R., Gray, E.W., Noblet, R., Overmyer, J., Rodriguez, L.L. 2009. Experimental Transmission of Vesicular Stomatitis New Jersey Virus From Black Flies (Simulium vittatum) To Cattle: Clinical Outcome Is Determined By Site of Insect Feeding. Journal of Medical Entomology. 46(4):866-872.
Field Evaluation of a Multiplex Real-Time Reverse Transcription Polymerase Chain Reaction Assay for Detection of Vesicular Stomatitis Virus - (Peer Reviewed Journal)
Wilson, W.C., Letchworth, G., Jimenez, C., Herraro, M., Navarro, R., Paz, P., Cornish, T.E., Smoliga, G.R., Pauszek, S.J., Dornak, C., George, M., Rodriguez, L.L. 2009. Field Evaluation of a Multiplex Real-Time Reverse Transcription Polymerase Chain Reaction Assay for Detection of Vesicular Stomatitis Virus. Journal of Veterinary Diagnostic Investigation. 21(2):179-186.
Rapid Preclinical Detection of Sheeppox Virus by a Real-Time PCR Assay - (Peer Reviewed Journal)
Balinsky, C.A., Delhon, G., Smoliga, G.R., Prarat, M., French, R.A., Geary, S.J., Rock, D.L., Rodriguez, L.L. 2008. Rapid Preclinical Detection of Sheeppox Virus by a Real-Time PCR Assay. Journal of Clinical Microbiology. 46(2):438-442.
Diagnostic evaluation of a reverse transcribed real time PCR assay for vesicular stomatitis in horses - (Abstract Only)
Koster, L., Landgraf, J., Swenson, S., Rodamaker, M., Emery, M., Smoliga, G.R., Rodriguez, L.L. 2005. Diagnostic evaluation of a reverse transcribed real time PCR assay for vesicular stomatitis in horses. American Association of Veterinary Laboratory Diagnosticians 48th Annual Conference. P. 92.
Validation of a real-time RT-PCR for vesicular stomatitis virus - (Abstract Only)
Letchworth, G., Jimenez, C., Herrero, M., Cornish, T., Wilson, W.C., Smoliga, G.R., Pauszek, S.J., Dornak, C., George, M., Rodriguez, L.L. 2004. Validation of a real-time RT-PCR for vesicular stomatitis virus. Proc. Am. Assoc. of Vet. Lab. Diagn. 47:121. 2004.
VALIDATION OF A REAL-TIME RT-PCR FOR VESICULAR STOMATITIS VIRUS - (Proceedings)
Rodriguez, L.L., Jimenez, C., Herrero, M., Cornish, T.E., Wilson, W.C., Letchworth, G.J., Pauszek, S.J., George, M., Smoliga, G.R. 2004. Validation of a real-time rt-pcr for vesicular stomatitis virus. American Association of Veterinary Laboratory Diagnosticians. P. 40