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ARS Home » Northeast Area » Orient Point, New York » Plum Island Animal Disease Center » Foreign Animal Disease Research » Research » Publications at this Location » Publication #339062

Research Project: Intervention Strategies to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus (FMDV)

Location: Foreign Animal Disease Research

Title: Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015

Author
item Arzt, Jonathan
item Brito, Barbara - Oak Ridge Institute For Science And Education (ORISE)
item Pauszek, Steven
item Hartwig, Ethan
item Smoliga, George
item Vu, Le - Ministry Of Agriculture And Rural Development (MARD)
item Vu, Pham - Ministry Of Agriculture And Rural Development (MARD)
item Stenfeldt, Carolina - Oak Ridge Institute For Science And Education (ORISE)
item Rodriguez, Luis
item Long, Ngo - Ministry Of Agriculture And Rural Development (MARD)
item Dung, Do - Ministry Of Agriculture And Rural Development (MARD)

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/15/2017
Publication Date: 5/4/2017
Citation: Arzt, J., Brito, B.P., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Vu, P.P., Stenfeldt, C., Rodriguez, L.L., Long, N.T., Dung, D.H. 2017. Genome sequence of foot-and-mouth disease virus serotype O lineage ind-2001d collected in Vietnam in 2015. Genome Announcements. 5(18):e00223-17. doi: 10.1128/genomeA.00223-17.

Interpretive Summary: Foot-and-mouth disease (FMD) is an important livestock disease that causes substantial animal health problems in several countries in Africa and Asia. There are seven different types of FMD virus (FMDV), which is the agent that causes the disease. Three of these types are normally found in mainland Southeast Asia. Within each type of the virus, there are also several different subtypes and lineages. In 2015, a specific FMDV lineage known as Ind-2001 was detected for the first time in Southeast Asia. This lineage originated in India, and has only rarely been detected elsewhere. This report contains the first near-complete genome sequence of a virus from this lineage collected from an outbreak in Vietnam. The finding of this new lineage of FMDV within this geographic region is of great importance FMD control measures.

Technical Abstract: Foot-and-mouth disease (FMD) is endemic in several countries in Asia and Africa and is considered one of the most important livestock diseases worldwide. Three serotypes of FMD virus (A, O and Asia1) contribute to endemicity in mainland Southeast Asia. In 2015, FMDV lineage Ind-2001 was detected for the first time in Southeast Asia. This report contains the first near-complete genome of a viral isolate from this lineage collected from an outbreak in Vietnam. This novel incursion has substantial implications for regional FMD control measures.