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ARS Home » Southeast Area » Little Rock, Arkansas » Arkansas Children's Nutrition Center » Research » Research Project #436033

Research Project: Impact of Maternal Influence and Early Dietary Factors on Child Growth, Development, and Metabolic Health

Location: Arkansas Children's Nutrition Center

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

C-section increases cecal abundance of the archetypal bile acid and glucocorticoid modifying Lachnoclostridium [Clostridium] scindens in mice - (Peer Reviewed Journal)

Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Sharma, A.K., Gurung, M., Casero, D., Matazel, K., Bode, L., Simecka, C., Elolimy, A.A., Tripp, P., Randolph, C., Hand, T.W., Williams, K.D., Leroith, T., Fox, R., Yeruva, V. 2022. Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.907529.

Effect of excess weight and insulin resistance on DNA methylation in prepubertal children Reprint Icon - (Peer Reviewed Journal)
Barbosa, P., Landes, R.D., Graw, S., Byrum, S.D., Bennuri, S., Delhey, L., Randolph, C., Macleod, S., Reis, A., Borsheim, E., Rose, S., Carvalho, E. 2022. Effect of excess weight and insulin resistance on DNA methylation in prepubertal children. Scientific Reports. https://doi.org/10.1038/s41598-022-12325-y.

Redox imbalance and methylation disturbances in early childhood obesity - (Peer Reviewed Journal)
Barbosa, P., Melnyk, S., Bennuri, S.C., Delhey, L., Reis, A., Moura, G.R., Borsheim, E., Rose, S., Carvalho, E. 2021. Redox imbalance and methylation disturbances in early childhood obesity. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2021/2207125.

Myoglobin interaction with lactate rapidly releases oxygen: Studies on binding thermodynamics, spectroscopic and oxygen kinetics Reprint Icon - (Peer Reviewed Journal)
Adepu, K., Bhandari, D., Anishkin, A., Adams, S.H., Chintapalli, S.V. 2022. Myoglobin interaction with lactate rapidly releases oxygen: Studies on binding thermodynamics, spectroscopic and oxygen kinetics. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms23094747.

Metabolomic signatures of low and high adiposity neonates differ based on maternal BMI - (Peer Reviewed Journal)

The effect of beef and beef's nutrients on well-being and quality of life in healthy adults >= 50 years to promote successful aging: A systematic review and meta-analysis of randomized control trials Reprint Icon - (Review Article)
Hawley, A., Liang, X., Borsheim, E., Wolfe, R.R., Salisbury, L., Wu, H., Walker, S., Tacinelli, A.M., Baum, J.I. 2022. The effect of beef and beef's nutrients on well-being and quality of life in healthy adults >= 50 years to promote successful aging: A systematic review and meta-analysis of randomized control trials. Meat Science. https://doi.org/10.1016/j.meatsci.2022.108830.

GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice Reprint Icon - (Peer Reviewed Journal)
Chen, J., Lazarenko, O., Blackburn, M.L. 2022. GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice. Bone. https://doi.org/10.1016/j.bone.2022.116422.

Breastfeeding duration modifies the association between maternal weight status and offspring dietary fat oxidation - (Peer Reviewed Journal)

Associations between maternal obesity and offspringgut microbiome in the first year of life Reprint Icon - (Peer Reviewed Journal)
Gilley, S.P., Ruebel, M.L., Sims, C., Zhong, Y., Turner, D., Lan, R.S., Pack, L.M., Piccolo, B.D., Abraham, A., Bode, L., Andres, A., Shankar, K. 2022. Associations between maternal obesity and offspringgut microbiome in the first year of life. Pediatric Obesity. https://doi.org/10.1111/ijpo.12921.

Circulating microRNAs are associated with metabolic markers in adolescents with hepatosteatosis Reprint Icon - (Peer Reviewed Journal)
Lin, H., Mercer, K., Ou, X., Mansfield, K., Buchmann, R., Borsheim, E., Tas, E. 2022. Circulating microRNAs are associated with metabolic markers in adolescents with hepatosteatosis. Frontiers in Endocrinology. https://doi.org/10.3389/fendo.2022.856973.

Soy formula is not estrogenic and does not result in reproductive toxicity in male piglets: Results from a controlled feeding study Reprint Icon - (Peer Reviewed Journal)
Ronis, M., Gomez-Acevedo, H., Shankar, K., Hennings, L., Sharma, N., Blackburn, M.L., Miousee, I., Dawson, H.D., Chen, C.T., Mercer, K.E., Badger, T.M. 2022. Soy formula is not estrogenic and does not result in reproductive toxicity in male piglets: Results from a controlled feeding study. Nutrients. 14(5):1126. https://doi.org/10.3390/nu14051126.

Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk Reprint Icon - (Peer Reviewed Journal)
Elolimy, A., Rosa, F., Tripp, P., Bowlin, A.K., Randolph, C., Robeson, M., Yeruva, V. 2022. Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2022.801854.

Effect of obesity on arithmetic processing in preteens with high and low math skills. An event-related potentials study Reprint Icon - (Peer Reviewed Journal)
Alatorre-Cruz, G., Downs, H., Hagood, H., Sorensen, S.T., Williams, D., Larson-Prior, L. 2022. Effect of obesity on arithmetic processing in preteens with high and low math skills. An event-related potentials study. Frontiers in Human Neuroscience. https://doi.org.10.3389/fnhum.2022.760234.

Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity Reprint Icon - (Peer Reviewed Journal)
Allman, B.R., Spray, B.J., Lan, R.S., Andres, A., Borsheim, E. 2022. Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00712.2021.

Neural correlates of sleep quality in children: Sex-specific associations shown by brain diffusion tractography Reprint Icon - (Peer Reviewed Journal)
Raja, R., Na, X., Badger, T.M., Ou, X. 2022. Neural correlates of sleep quality in children: Sex-specific associations shown by brain diffusion tractography. Journal of Neuroimaging. https://doi.org/10.1111/jon.12964.

Maternal obesity programming of perivascular adipose tissue and associated immune cells: An understudied area with few answers and many questions Reprint Icon - (Review Article)
Corken, A., Thakali, K.M. 2022. Maternal obesity programming of perivascular adipose tissue and associated immune cells: An understudied area with few answers and many questions. Frontiers in Psychology. https://doi.org/10.3389/fphys.2021.798987.

Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies Reprint Icon - (Peer Reviewed Journal)
Pace, R.M., Williams, J.E., Järvinen, K.M., Meehan, C.L., Martin, M.A., Ley, S.H., Barbosa-Leiker, C., Andres, A., Yeruva, V., Belfort, M.B., Caffe, B., Navarrete, A.D., Lackey, K.A., Pace, C., Gogel, A.C., Fehrenkamp, B.D., Klein, M., Young, B., Rosen-Carole, C., Diaz, N., Gaw, S.L., Flaherman, V., Mcguire, M.A., Mcguire, M.K., Seppo, A. 2021. Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2021.801797.

Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index - (Peer Reviewed Journal)

Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Zybailov, B., Glazko, G.V., Rahmatallah, Y., Byrum, S., Mackintosh, S.G., Bowlin, A.K., Yeruva, V. 2021. Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model. Nutrients. 13(11):3718. https://doi.org/10.3390/nu13113718.

Digital intervention strategies for increasing physical activity among preschoolers: Systematic review Reprint Icon - (Review Article)
Swindle, T., Poosala, A.B., Zeng, N., Borsheim, E., Andres, A., Bellows, L.L. 2022. Digital intervention strategies for increasing physical activity among preschoolers: Systematic review. Journal of Medical Internet Research. 24(1):e28230. https://doi.org/10.2196/28230.

Using resistance training in women with gestational diabetes mellitus to improve glucose regulation Reprint Icon - (Book / Chapter)
Allman, B.R., Mcdonald, S., May, L., Kinsey, A.W., Borsheim, E. 2021. Using resistance training in women with gestational diabetes mellitus to improve glucose regulation. IntechOpen. https://doi.org/10.5772/intechopen.101076.

Structural and energetic insights into the interaction of niacin with GPR109A receptor Reprint Icon - (Peer Reviewed Journal)
Adepu, K., Kachhap, S., Anishkin, A., Chintapalli, S.V. 2021. Structural and energetic insights into the interaction of niacin with GPR109A receptor. Bioinformatics and Biology Insights. https://doi.org/10.1177/11779322211056122.

Associations between maternal diet, body composition and gut microbial ecology in pregnancy Reprint Icon - (Peer Reviewed Journal)
Ruebel, M.L., Gilley, S.P., Sims, C.R., Zhong, Y., Turner, D., Chintapalli, S.V., Piccolo, B.D., Andres, A., Shankar, K. 2021. Associations between maternal diet, body composition and gut microbial ecology in pregnancy. Nutrients. https://doi.org/10.3390/nu13093295.

Maternal obesity during pregnancy is associated with lower cortical thickness in the newborn brain Reprint Icon - (Peer Reviewed Journal)
Na, X., Phelan, N.E., Tadros, M.R., Wu, Z., Andres, A., Badger, T.M., Glasier, C.M., Ramakrishnaiah, R.R., Rowell, A.C., Wang, L., Li, G., Williams, D.K., Ou, X. 2021. Maternal obesity during pregnancy is associated with lower cortical thickness in the newborn brain. American Journal of Neuroradiology. https://doi.org/10.3174/ajnr.A7316.

Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: Protocol for a randomized controlled trial Reprint Icon - (Peer Reviewed Journal)
Fawcett, K., Martinez, A., Crimmins, M., Sims, C., Borsheim, E., Andres, A. 2021. Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: Protocol for a randomized controlled trial. Biomed Central (BMC) Nutrition. 7:51. https://doi.org/10.1186/s40795-021-00454-y.

Maternal and early-life factors influence on human milk composition and infants' gut health Reprint Icon - (Review Article)
Rosa, F., Dague, T.D., Laura, C., Andres, A., Yeruva, L. 2021. Maternal and early-life factors influence on human milk composition and infants' gut health. Reference Module in Food Science. https://doi.org/10.1016/B978-0-12-819265-8.00062-0.

Supervised resistance training on functional capacity, muscle strength and vascular function in peripheral artery disease: An updated systematic review and meta-analysis Reprint Icon - (Review Article)
Blears, E.E., Elias, J.K., Tapking, C., Porter, C., Rontoyanni, V.G. 2021. Supervised resistance training on functional capacity, muscle strength and vascular function in peripheral artery disease: An updated systematic review and meta-analysis. Journal of Clinical Medicine. 10(10):2193. https://doi.org/10.3390/jcm10102193.

Dietary protein requirements in children: Methods for consideration Reprint Icon - (Review Article)
Hudson, J.L., Baum, J.I., Diaz, E.C., Borsheim, E. 2021. Dietary protein requirements in children: Methods for consideration. Nutrients. 13:1554. https://doi.org/10.3390/nu13051554.

On the potential role of globins in brown adipose tissue: A novel conceptual model and studies in myoglobin knockout mice Reprint Icon - (Peer Reviewed Journal)
Blackburn, M.L., Wankhade, U.D., Ono-Moore, K.D., Chintapalli, S.V., Fox, R., Rutkowsky, J.M., Willis, B.J., Tolentino, T., Lloyd, K., Adams, S.H. 2021. On the potential role of globins in brown adipose tissue: A novel conceptual model and studies in myoglobin knockout mice. American Journal of Physiology - Endocrinology and Metabolism. 321(1):E47-E62. https://doi.org/10.1152/ajpendo.00662.2020.

Cardiorespiratory fitness associates with blood pressure and metabolic health of children - The Arkansas Active Kids Study Reprint Icon - (Peer Reviewed Journal)
Diaz, E.C., Weber, J., Ferruzzi, M.H., Gomes Young, C., Bai, S., Borsheim, E. 2021. Cardiorespiratory fitness associates with blood pressure and metabolic health of children - The Arkansas Active Kids Study. Medicine and Science in Sports and Exercise. https://doi.org/10.1249/MSS.0000000000002701.

Short-term increased physical activity during early life affects high-fat diet-induced bone loss in young adult mice Reprint Icon - (Peer Reviewed Journal)
Chen, J., Lazarenko, O.P., Carvalho, E., Blackburn, M.L., Shankar, K., Wankhade, U.D., Borsheim, E. 2021. Short-term increased physical activity during early life affects high-fat diet-induced bone loss in young adult mice. JBMR Plus. https://doi.org/10.1002/jbm4.10508.

Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice Reprint Icon - (Peer Reviewed Journal)
Ono-Moore, K., Olfert, M., Rutkowsky, J.M., Chintapalli, S.V., Willis, B., Blackburn, M.L., Williams, D., O'Reilly, J., Tolentino, T., Lloyd, K., Adams, S.H. 2021. Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice. American Journal of Physiology - Endocrinology and Metabolism. 321(1):E63-E79. https://doi.org/10.1152/ajpendo.00624.2020.

Effect of obesity on inhibitory control in preadolescents during stop-signal task. An event-related potentials study Reprint Icon - (Peer Reviewed Journal)
Alatorre-Cruz, G.C., Downs, H., Hagood, D., Sorenson, S.T., Williams, D.K., Larson-Prior, L. 2021. Effect of obesity on inhibitory control in preadolescents during stop-signal task. An event-related potentials study. International Journal of Psychophysiology. 165:56-67. https://doi.org/10.1016/j.ijpsycho.2021.04.003.

Infant intakes of human milk amino acids are associated with maternal obesity and infant growth - (Abstract Only)

Adipocyte browning in response to trauma: Some important methodological considerations - (Other)

Effect of obesity on arithmetic processing in preteens with high and low math skill - (Abstract Only)

Editorial: Impact of early life nutrition on immune system development and related health outcomes in later life Reprint Icon - (Review Article)
Yeruva, L., Munblit, D., Collado, M. 2021. Editorial: Impact of early life nutrition on immune system development and related health outcomes in later life. Frontiers in Immunology. 12:668569. https://doi.org/10.3389/fimmu.2021.668569.

Predictors of platelet mitochondria respiration in children – The Arkansas Active Kids Study - (Abstract Only)

Maternal obesity during pregnancy is associated with lower cortical thickness in the newborn brain - (Abstract Only)

Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women Reprint Icon - (Peer Reviewed Journal)
Mercer, K.E., Maurer, A., Pack, L.M., Ono-Moore, K., Spray, B.J., Campbell, C., Chandler, C., Burnett, D., Souza, E., Casazza, G., Keim, N., Newman, J., Hunter, G., Fernadez, J., Garvey, T.W., Harper, M., Hoppel, C., Adams, S.H., Thyfault, J. 2021. Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women. American Journal of Physiology - Endocrinology and Metabolism. 320(5):E864-E873. https://doi.org/10.1152/ajpendo.00644.2020.

Human milk oligosaccharide concentrations and infant intakes are associated with maternal overweight and obesity and predict infant growth Reprint Icon - (Peer Reviewed Journal)
Saben, J.L., Sims, C.R., Abraham, A., Bode, L., Andres, A. 2021. Human milk oligosaccharide concentrations and infant intakes are associated with maternal overweight and obesity and predict infant growth. Nutrients. https://doi.org/10.3390/nu13020446.

Role of human milk bioactives on infants' gut and immune health Reprint Icon - (Review Article)
Carr, L.E., Virmani, M.D., Rosa, F., Munblit, D., Matazel, K.S., Elolimy, A., Yeruva, L. 2021. Role of human milk bioactives on infants' gut and immune health. Frontiers in Immunology. 12:604080. https://doi.org/10.3389/fimmu.2021.604080.

Human milk-fed piglets have a distinct small intestine and circulatory metabolome profile relative to that of milk formula-fed piglets Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Matazel, K.S., Elolimy, A.A., Adams, S.H., Bowlin, A., Williams, K.D., Bode, L., Yeruva, L. 2021. Human milk-fed piglets have a distinct small intestine and circulatory metabolome profile relative to that of milk formula-fed piglets. mSystems. https://doi.org/10.1128/mSystems.01376-20.

Effect of obesity on inhibitory control in preadolescents during stop-signal task. An event-related potentials study - (Abstract Only)

Markers of branched-chain amino acid catabolism are not affected by exercise training in pregnant women with obesity Reprint Icon - (Peer Reviewed Journal)
Allman, B.R., Spray, B.J., Mercer, K.E., Andres, A., Borsheim, E. 2021. Markers of branched-chain amino acid catabolism are not affected by exercise training in pregnant women with obesity. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00673.2020.

Beige adipose tissue identification and marker specificity-overview Reprint Icon - (Review Article)
Pilkington, A., Paz, H.A., Wankhade, U.D. 2021. Beige adipose tissue identification and marker specificity-overview. Frontiers in Endocrinology. https://doi.org/10.3389/fendo.2021.599134.

Association between home environment in infancy and child movement behaviors Reprint Icon - (Peer Reviewed Journal)
Kracht, C.L., Redman, L.M., Casey, P.H., Krukowski, R.A., Andres, A. 2021. Association between home environment in infancy and child movement behaviors. Childhood Obesity. 17(2):100-109. https://doi.org/10.1089/chi.2020.0319.

GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice Reprint Icon - (Peer Reviewed Journal)
Chen, J., Zhao, H., Wankhade, U.D., Chintapalli, S.V., Li, C., Gai, D., Shankar, K., Zhan, F., Lazarenko, O.P. 2021. GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice. Communications Biology. 4:53. https://doi.org/10.1038/s42003-020-01564-2.

Early infant formula feeding impacts urinary metabolite profile at 3 months of age Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Mercer, K., Lin, H., Sims, C.R., Pack, L.M., Good, G., Badger, T.M., Andres, A., Yeruva, L. 2020. Early infant formula feeding impacts urinary metabolite profile at 3 months of age. Nutrients. 12(11):3552. https://doi.org/10.3390/nu12113552.

Neonatal diet impacts the large intestine luminal metabolome at weaning and post-weaning in piglets fed formula or human milk Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Matazel, K.S., Bowlin, A.K., Williams, K.D., Elolimy, A.A., Adams, S.H., Bode, L., Yeruva, L. 2020. Neonatal diet impacts the large intestine luminal metabolome at weaning and post-weaning in piglets fed formula or human milk. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2020.607609.

The Arkansas active kids study: Identifying contributing factors to metabolic health and obesity status in prepubertal school-age children Reprint Icon - (Peer Reviewed Journal)
Bai, S., Goudie, A., Borsheim, E., Weber, J.L. 2020. The Arkansas active kids study: Identifying contributing factors to metabolic health and obesity status in prepubertal school-age children. Journal of Nutrition and Health. https://doi.org/10.1177/0260106020975571.

Circulating miRNA signatures associated with insulin resistance in adolescents with obesity Reprint Icon - (Peer Reviewed Journal)
Lin, H., Tas, E., Borsheim, E., Mercer, K.E. 2020. Circulating miRNA signatures associated with insulin resistance in adolescents with obesity. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13:4929–4939. https://doi.org/10.2147/DMSO.S273908.

Human milk and dairy-based formula impact large intestine metabolome profile in a neonatal porcine model - (Abstract Only)

Adults who are overweight or obese and consuming an energy-restricted healthy US-style eating pattern at either the recommended or a higher protein quantity perceive a shift from "poor" to "good" sleep Reprint Icon - (Peer Reviewed Journal)
Hudson, J.L., Zhou, J., Campbell, W.W. 2020. Adults who are overweight or obese and consuming an energy-restricted healthy US-style eating pattern at either the recommended or a higher protein quantity perceive a shift from "poor" to "good" sleep: A randomized controlled trial. Journal of Nutrition. 150(12):3216-3223. https://doi.org/10.1093/jn/nxaa302.

Early infant feeding effect on growth and body composition during the first 6 years and neurodevelopment at age 72 months Reprint Icon - (Peer Reviewed Journal)
Sobik, S., Sims, C., Mckorkle, G., Bellando, J., Sorensen, S., Badger, T.M., Casey, P., Williams, K.D., Andres, A. 2020. Early infant feeding effect on growth and body composition during the first 6 years and neurodevelopment at age 72 months. Pediatric Research. https://doi.org/10.1038/s41390-020-01157-z.

Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling Reprint Icon - (Peer Reviewed Journal)
Bose, C., Alves, I., Singh, P., Palade, P.T., Carvalho, E., Borsheim, E., Jun, S., Cheema, A., Boerma, M., Awasthi, S., Singh, S.P. 2020. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell. 19:e13261. https://doi.org/10.1111/acel.13261.

Divergence in aerobic capacity impacts bile acid metabolism in young women - (Peer Reviewed Journal)
Maurer, A., Ward, J., Dean, K., Billinger, S.A., Lin, H., Mercer, K.E., Adams, S.H., Thyfault, J. 2020. Divergence in aerobic capacity impacts bile acid metabolism in young women. Journal of Applied Physiology. 129(4):768-778. https://doi.org/pubmed.ncbi.nlm.nih.gov/32853107/.

Documenting and characterising gestational weight gain beliefs and experiences among Marshallese pregnant women in Arkansas: A protocol for a longitudinal mixed-methods study Reprint Icon - (Peer Reviewed Journal)
Ayers, B.L., Bogulski, C.A., Haggard-Duff, L., Andres, A., Borsheim, E., McElfish, P.A. 2020. Documenting and characterising gestational weight gain beliefs and experiences among Marshallese pregnant women in Arkansas: A protocol for a longitudinal mixed-methods study. BMJ Open. 10:e037219. https://doi.org/10.1136/bmjopen-2020-037219.

Fibroblast growth factor-21 to adiponectin ratio: A potential biomarker to monitor liver fat in children with obesity Reprint Icon - (Peer Reviewed Journal)
Tas, E., Bai, S., Ou, X., Mercer, K., Lin, H., Mansfield, K., Buchmann, R., Diaz, E.C., Oden, J., Borsheim, E., Adams, S.H., Dranoff, J. 2020. Fibroblast growth factor-21 to adiponectin ratio: A potential biomarker to monitor liver fat in children with obesity. Frontiers in Endocrinology. https://doi.org/10.3389/fendo.2020.00654.

Adaptation of an exercise intervention for pregnant women to community-based delivery: A study protocol Reprint Icon - (Peer Reviewed Journal)
Swindle, T., Martinez, A., Borsheim, E., Andres, A. 2020. Adaptation of an exercise intervention for pregnant women to community-based delivery: A study protocol. BMJ Open. 10:e038582. https://doi.org/10.1136/bmjopen-2020-038582.

Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women Reprint Icon - (Peer Reviewed Journal)
Grapov, D., Fiehn, O., Campbell, C., Chandler, C.J., Burnett, D.J., Souza, E.C., Casazza, G.A., Keim, N.L., Hunter, G.R., Fernandez, J.R., Garvey, T., Hoppel, C.L., Harper, M., Newman, J.W., Adams, S.H. 2020. Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women. Physiological Reports. 8(17). Article e14547. https://doi.org/10.14814/phy2.14547.

Formula diet alters ileal metagenome and transcriptome at weaning and during the postweaning period in a porcine model Reprint Icon - (Peer Reviewed Journal)
Elolimy, A., Washam, C., Byrum, S., Chen, C.T., Dawson, H.D., Bowlin, A.K., Randolph, C., Saraf, M.K., Yeruva, L. 2020. Formula diet alters ileal metagenome and transcriptome at weaning and during the postweaning period in a porcine model. mSystems. 5:e00457-20. https://doi.org/10.1128/mSystems.00457-20.

Third-trimester glucose homeostasis in healthy women is differentially associated with human milk oligosaccharide composition at 2 months postpartum by secretor phenotype Reprint Icon - (Peer Reviewed Journal)
Saben, J.L., Abraham, A., Bode, L., Sims, C.R., Andres, A. 2020. Third-trimester glucose homeostasis in healthy women is differentially associated with human milk oligosaccharide composition at 2 months postpartum by secretor phenotype. Nutrients. 12(8):2209. https://doi.org/10.3390/nu12082209.

Coupling of energy intake and energy expenditure across a temperature spectrum: Impact of diet-induced obesity in mice Reprint Icon - (Peer Reviewed Journal)
Ono-Moore, K., Rutkowsky, J.M., Pearson, N.A., Williams, D., Grobe, J.L., Tolentino, T., Kent Lloyd, K., Adams, S.H. 2020. Coupling of energy intake and energy expenditure across a temperature spectrum: Impact of diet-induced obesity in mice. American Journal of Physiology - Endocrinology and Metabolism. 319:E472-E484. https://doi.org/10.1152/ajpendo.00041.2020.

The role of human breast milk extracellular vesicles in child health and disease: A scoping review Reprint Icon - (Review Article)
O'Reilly, D., Dorodnykh, D., Avdeenko, N.V., Nekliudov, N.A., Garssen, J., Elolimy, A., Petrou, L., Simpson, M., Yeruva, L., Munblit, D. 2020. The role of human breast milk extracellular vesicles in child health and disease: A scoping review. Advances in Nutrition. 12(1):59-70. https://doi.org/10.1093/advances/nmaa094.

Maternal anxiety and depression during late pregnancy and newborn's brain white matter development Reprint Icon - (Peer Reviewed Journal)
Graham, R., Jiang, L., Mccorkle, G., Bellando, B., Sorensen, S., Glasier, C., Ramakrishnaiah, R., Rowell, A., Coker, J., Ou, X. 2020. Maternal anxiety and depression during late pregnancy and newborn's brain white matter development. American Journal of Neuroradiology. 41(10):1908-1915. https://doi.org/10.3174/ajnr.A6759.

Maternal adiposity alters the human milk metabolome: Associations between non-glucose monosaccharides and infant adiposity Reprint Icon - (Peer Reviewed Journal)
Saben, J.L., Sims, C.R., Piccolo, B.D., Andres, A. 2020. Maternal adiposity alters the human milk metabolome: Associations between non-glucose monosaccharides and infant adiposity. American Journal of Clinical Nutrition. 112(5):1228-1239. https://doi.org/10.1093/ajcn/nqaa216.

Cortical morphometry is associated with neuropsychological function in healthy 8-year-old children Reprint Icon - (Peer Reviewed Journal)
Li, T., McCorkle, G.S., Williams, D.K., Badger, T.M., Ou, X. 2020. Cortical morphometry is associated with neuropsychological function in healthy 8-year-old children. Journal of Neuroimaging. 30(6):833-842. https://doi.org/10.1111/jon.12754.

Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs Reprint Icon - (Peer Reviewed Journal)
Mercer, K.E., Ten Have, G., Pack, L., Lan, R., Deutz, N., Adams, S.H., Piccolo, B.D. 2020. Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs. American Journal of Physiology - Gastrointestinal and Liver Physiology. 319(2):G133-G141. https://doi.org/10.1152/ajpgi.00153.2020.

Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites Reprint Icon - (Peer Reviewed Journal)
Mercer, K.E., Yeruva, L., Pack, L., Graham, J.L., Stanhope, K.L., Chintapalli, S.V., Wankhade, U.D., Shankar, K., Havel, P.J., Adams, S.H., Piccolo, B.D. 2020. Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites. American Journal of Physiology - Gastrointestinal and Liver Physiology. 319(2):G157-G169. https://doi.org/10.1152/ajpgi.00105.2020.

Metabolic effects of late dinner in healthy volunteers – A randomized crossover clinical trial Reprint Icon - (Peer Reviewed Journal)
Gu, C., Brereton, N., Schweitzer, A., Cotter, M., Duan, D., Borsheim, E., Wolfe, R.R., Pham, L.V., Polotsky, V.Y., Jun, J.C. 2020. Metabolic effects of late dinner in healthy volunteers – A randomized crossover clinical trial. Journal of Clinical Endocrinology and Metabolism. https://doi.org/10.1210/clinem/dgaa354.

Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mice offspring Reprint Icon - (Peer Reviewed Journal)
Harris, J.E., Pinckard, K.M., Wright, K.R., Baer, L.A., Arts, P.J., Abay, E., Shettigar, V.K., Lehnig, A.C., Roberston, B., Madaris, K., Canova, T.J., Sims, C., Goodyear, L.J., Andres, A., Ziolo, M.T., Bode, L., Stanford, K.I. 2020. Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mice offspring. Nature Metabolism. https://doi.org/10.1038/s42255-020-0223-8.

Mitochondrial physiology Reprint Icon - (Review Article)
Gnaiger, E., MitoEAGLE Task Group. 2020. Mitochondrial physiology. Bioenergetics Communications. 2020.1. https://doi.org/10.26124/bec:2020-0001.v1.

Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes Reprint Icon - (Peer Reviewed Journal)
Blackburn, M.L., Ono-Moore, K.D., Sobhi, H.F., Adams, S.H. 2020. Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes. American Journal of Physiology - Endocrinology and Metabolism. 319(2):E265-E275. https://doi.org/10.1152/ajpendo.00515.2019.

Neonatal diet impacts circulatory miRNA profile in a porcine model Reprint Icon - (Peer Reviewed Journal)
Carr, L.E., Bowlin, A.K., Elolimy, A.E., Byrum, S.D., Washam, C.L., Randolph, C.E., Macleod, S.L., Yeruva, L. 2020. Neonatal diet impacts circulatory miRNA profile in a porcine model. Frontiers in Immunology. 11:1240. https://doi.org/10.3389/fimmu.2020.01240.

Protein distribution and muscle-related outcomes: Does the evidence support the concept? Reprint Icon - (Review Article)
Hudson, J.L., Bergia III, R.E., Campbell, W.W. 2020. Protein distribution and muscle-related outcomes: Does the evidence support the concept? Nutrients. 12(5):1441. https://doi.org/10.3390/nu12051441.

Nox4 expression is not required for OVX-induced osteoblast senescence and bone loss in mice Reprint Icon - (Peer Reviewed Journal)
Chen, J., Lazarenko, O.P., Zhao, H., Wankhade, U.D., Pedersen, K., Watt, J., Ronis, M. 2020. Nox4 expression is not required for OVX-induced osteoblast senescence and bone loss in mice. JBMR Plus. https://doi.org/10.1002/jbm4.10376.

Potential role of gut microbiota, the proto-oncogene PIKE (Agap2) and cytochrome P450 CYP2W1 in promotion of liver cancer by alcoholic and nonalcoholic fatty liver disease and protection by dietary soy protein Reprint Icon - (Peer Reviewed Journal)
Ronis, M.J., Mercer, K.E., Shankar, K., Pulliam, C., Pedersen, K., Ingelman-Sundberg, M., Friso, S., Samuelsona, D., Del Valle, L., Taylor, C., Welsh, D.A. 2020. Potential role of gut microbiota, the proto-oncogene PIKE (Agap2) and cytochrome P450 CYP2W1 in promotion of liver cancer by alcoholic and nonalcoholic fatty liver disease and protection by dietary soy protein. Chemico Biological Interactions. 325:109131. https://doi.org/10.1016/j.cbi.2020.109131.

Role of bacterial infections in extracellular vesicles release and impact on immune response Reprint Icon - (Review Article)
Spencer, N., Yeruva, V. 2020. Role of bacterial infections in extracellular vesicles release and impact on immune response. BioMedical Journal. https://doi.org/10.1016/j.bj.2020.05.006.

Dietary protein intake during pregnancy is not associated with offspring insulin sensitivity Reprint Icon - (Peer Reviewed Journal)
Allman, B.R., Williams, D., Borsheim, E., Andres, A. 2020. Dietary protein intake during pregnancy is not associated with offspring insulin sensitivity. Nutrients. 12(5):1338. https://doi.org/10.3390/nu12051338.

Human milk composition differs by maternal BMI in the first 9 months postpartum Reprint Icon - (Peer Reviewed Journal)
Sims, C.R., Lipsmeyer, M.E., Turner, D.E., Andres, A. 2020. Human milk composition differs by maternal BMI in the first 9 months postpartum. American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/nqaa098.

Changes in polyphenolics during storage of products prepared with freeze-dried wild blueberry powder Reprint Icon - (Peer Reviewed Journal)
Lavefve, L., Brownmiller, C., Howard, L., Reeves, D., Adams, S.H., Chen, J., Diaz, E., Mauromoustakos, A. 2020. Changes in polyphenolics during storage of products prepared with freeze-dried wild blueberry powder. Foods. 9(4):466. https://doi.org/10.3390/foods9040466.

MicroRNA profiles were altered in neonatal piglet mammary glands following postnatal infant formula feeding Reprint Icon - (Peer Reviewed Journal)
Lin, H., Chaudhury, M., Sharma, N., Bhattacharyya, S., Elolimy, A.A., Yeruva, L., Ronis, M., Mercer, K.E. 2020. MicroRNA profiles were altered in neonatal piglet mammary glands following postnatal infant formula feeding. Journal of Nutritional Biochemistry. https://doi.org/10.1016/j.jnutbio.2020.108397.

Body composition measurements from birth through 5 years: Challenges, gaps, and existing & emerging technologies—A National Institutes of Health workshop Reprint Icon - (Review Article)
Gallagher, D., Andres, A., Fields, D.A., Evans, W.J., Kuczmarski, R., Lowe Jr, W.L., Lumeng, J.C., Oken, E., Shepherd, J.A., Sun, S., Heymsfield, S.B. 2020. Body composition measurements from birth through 5 years: Challenges, gaps, and existing & emerging technologies—A National Institutes of Health workshop. Obesity Reviews. https://doi.org/10.1111/obr.13033.

Incorporating milk protein isolate into an energy-restricted western-style eating pattern augments improvements in blood pressure and triglycerides Reprint Icon - (Peer Reviewed Journal)
Hudson, J.L., Zhou, J., Kim, J., Campbell, W.W. 2020. Incorporating milk protein isolate into an energy-restricted western-style eating pattern augments improvements in blood pressure and triglycerides. Nutrients. 12(3):851. https://doi.org/10.3390/nu12030851.

Divergent changes in serum branched-chain amino acid concentrations and estimates of insulin resistance throughout gestation in healthy women Reprint Icon - (Peer Reviewed Journal)
Allman, B.R., Diaz, E.C., Andres, A., Borsheim, E. 2020. Divergent changes in serum branched-chain amino acid concentrations and estimates of insulin resistance throughout gestation in healthy women. Journal of Nutrition. https://doi.org/10.1093/jn/nxaa096.

Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk Reprint Icon - (Peer Reviewed Journal)
Carvalho, E., Adams, S.H., Borsheim, E., Blackburn, M.L., Ono-Moore, K.D., Cotter, M., Bowlin, A.K., Yeruva, L. 2020. Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk. Biomed Central (BMC) Nutrition. 6:13. https://doi.org/10.1186/s40795-020-00338-7.

Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans Reprint Icon - (Peer Reviewed Journal)
Sobhi, H.F., Zhao, X.J., Plomgaard, P., Hoene, M., Karus, B., Niess, A.M., Haring, H.U., Lehmann, R., Adams, S.H., Xu, G., Weigert, C. 2020. Identification and regulation of the xenometabolite derivatives cis- and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans. American Journal of Physiology - Endocrinology and Metabolism. 318(5):E701-E709. https://doi.org/10.1152/ajpendo.00510.2019.

Associations between maternal body mass index and diet composition with placental DNA methylation at term Reprint Icon - (Peer Reviewed Journal)
Thakali, K.M., Zhong, Y., Cleves, M., Andres, A., Shankar, K. 2020. Associations between maternal body mass index and diet composition with placental DNA methylation at term. Placenta. 93:74-82. https://doi.org/10.1016/j.placenta.2020.02.018.

Postnatal diet impact on microRNA expression - (Abstract Only)

Body composition, diet and developmental outcomes during the first 6 years of infants fed breastmilk, cow's milk or soy infant formula - (Abstract Only)

Maternal anxiety and depression during pregnancy and newborn's brain white matter development - (Abstract Only)

Infant diets, brain cortical development, and executive functions in children - (Abstract Only)

Metabolomics profiling in response to a cold pressor test - (Abstract Only)

Tight regulation of energy intake and expenditure across a temperature spectrum is disrupted at thermoneutrality - (Abstract Only)

Children's liking and wanting of foods vary over multiple bites/sips of consumption: A case study of food products containing wild blueberry powder in the amounts targeted to deliver bioactive phytonutrients for children Reprint Icon - (Peer Reviewed Journal)
Seo, H., Adams, S.H., Howard, L., Brownmiller, C., Hogan, V., Chen, J., Pramudya, R.C. 2020. Children's liking and wanting of foods vary over multiple bites/sips of consumption: A case study of food products containing wild blueberry powder in the amounts targeted to deliver bioactive phytonutrients for children. Food Research International. 131: 108981. https://doi.org/10.1016/j.foodres.2020.108981.

Evaluating body composition in infancy and childhood: A comparison between 4C, QMR, DXA, and ADP Reprint Icon - (Peer Reviewed Journal)
Heard-Lipsmeyer, M., Hull, H., Sims, C.R., Cleves, M.A., Andres, A. 2020. Evaluating body composition in infancy and childhood: A comparison between 4C, QMR, DXA, and ADP. Pediatric Obesity. https://doi.org/10.1111/ijpo.12617.

Divergent changes in plasma branched-chain amino acid concentrations and insulin resistance throughout gestation - (Abstract Only)

Cardiovascular disease risk factors and platelet mitochondrial function in school-age children - (Abstract Only)

Limited impact of myoglobin knockout on metabolic phenotype in mice fed a high fat diet - (Abstract Only)

Synthesis, spectroscopic characterization & detection of cyclopropyl heptanoylcarnitine stereoisomers in human plasma - (Abstract Only)

Carnitine palmitoyltransferase 2 (CPT2) knockout potentiates palmitate-induced insulin resistance in C2C12 myotubes: Role of palmitoylcarnitine - (Abstract Only)

Circulating miRNA signatures associated with NAFLD in obese adolescents - (Abstract Only)

Lactotrehalose, an analog of trehalose, increases energy metabolism without promoting clostridioides difficile infection in mice Reprint Icon - (Peer Reviewed Journal)
Zhang, Y., Shaikh, N., Ferey, J.L., Wankhade, U.D., Chintapalli, S.V., Higgins, C.B., Crowley, J.R., Heitmeier, M.R., Stothard, A.I., Mihi, B., Good, M.R., Higashiyama, T., Swart, B.M., Hruz, P.W., Shankar, K., Tarr, P.I., Debosch, B.J. 2019. Lactotrehalose, an analog of trehalose, increases energy metabolism without promoting clostridioides difficile infection in mice. Gastroenterology. https://doi.org/10.1053/j.gastro.2019.11.295.

Zero-inflated covariates: Should we care about it? - (Abstract Only)

Interactive and dynamic statistical reports using R shiny apps integrated with REDCap: Example from Arkansas Active Kids study - (Abstract Only)

Data from: Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: Impact of a fitness and weight loss intervention Reprint Icon - (Database / Dataset)
Adams, S.H. 2019. Data from: Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: Impact of a fitness and weight loss intervention. Ag Data Commons. https://doi.org/10.15482/USDA.ADC/1504422.

Obesity status affects the relationship between protein intake and insulin sensitivity in late pregnancy Reprint Icon - (Peer Reviewed Journal)
Allman, B.R., Fuentes, E., Williams, D., Turner, D.E., Andres, A., Borsheim, E. 2019. Obesity status affects the relationship between protein intake and insulin sensitivity in late pregnancy. Nutrients. 11(9):2190. https://doi.org/10.3390/nu11092190.

Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments Reprint Icon - (Peer Reviewed Journal)
Skinner, C.M., Miousse, I.R., Ewing, L.E., Sridharan, V., Cao, M., Lin, H., Williams, D.K., Avula, B., Haider, S., Amar, C.G., Khan, I.A., Elsohly, M.A., Boerma, M., Gurley, B.J., Koturbash, I. 2018. Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments. Food and Chemical Toxicology. 122:21-32. https://doi.org/10.1016/j.fct.2018.09.067.