Research Project: Genomic Intervention Strategies to Prevent and/or Treat Respiratory Diseases of Ruminants

Location: Animal Health Genomics

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Evaluating large spontaneous deletions in a bovine cell line selected for bovine viral diarrhea virus resistance - (Peer Reviewed Journal)
Workman, A.M., Heaton, M.P., Webster, D.A., Harhay, G.P., Kalbfleisch, T.S., Smith, T.P.L., Falkenberg, S.M., Carlson, D.F., Sonstegard, T.S. 2021. Evaluating large spontaneous deletions in a bovine cell line selected for bovine viral diarrhea virus resistance. Viruses. 13(11). Article 2147. https://doi.org/10.3390/v13112147.

Differences between predicted outer membrane proteins of Pasteurella multocida, Histophilus somni, and genotype 1 and 2 Mannheimia haemolytica strains isolated from cattle - (Peer Reviewed Journal)
Wynn, E.L., Clawson, M.L. 2021. Differences between predicted outer membrane proteins of Pasteurella multocida, Histophilus somni, and genotype 1 and 2 Mannheimia haemolytica strains isolated from cattle. Genome. https://doi.org/10.1139/gen-2021-0038.

Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns [version 2; revised] - (Peer Reviewed Journal)

Detection of bovine inflammatory cytokines IL-1ß, IL-6, and TNF-a with a multiplex electrochemiluminescent assay platform - (Peer Reviewed Journal)
Chitko-McKown, C.G., Bierman, S.L., Kuehn, L.A., Bennett, G.L., DeDonder, K.D., Apley, M.D., Harhay, G.P., Clawson, M.L., White, B.J., Larson, R.L., Capik, S.F., Lubbers, B.V. 2021. Detection of bovine inflammatory cytokines IL-1ß, IL-6, and TNF-a with a multiplex electrochemiluminescent assay platform. Veterinary Immunology and Immunopathology. 237. Article 110274. https://doi.org/10.1016/j.vetimm.2021.110274.

Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Ün, C., Heaton, M.P. 2021. Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep. Scientific Reports. 11. Article 7088. https://doi.org/10.1038/s41598-021-86605-4.

Component causes of infectious bovine keratoconjunctivitis - the role of Moraxella species in the epidemiology of infectious bovine keratoconjunctivitis - (Review Article)
Loy, J.D., Hille, M., Maier, G., Clawson, M.L. 2021. Component causes of infectious bovine keratoconjunctivitis - the role of Moraxella species in the epidemiology of infectious bovine keratoconjunctivitis. Veterinary Clinics of North America:Food Animal Practice. 37(2):279-293. https://doi.org/10.1016/j.cvfa.2021.03.004.

MALDI-TOF MS biomarker detection models to distinguish RTX toxin phenotypes of Moraxella bovoculi strains are enhanced using calcium chloride supplemented agar - (Peer Reviewed Journal)
Hille, M.M., Clawson, M.L., Dickey, A.M., Lowery, J.H., Loy, J.D. 2021. MALDI-TOF MS biomarker detection models to distinguish RTX toxin phenotypes of Moraxella bovoculi strains are enhanced using calcium chloride supplemented agar. Frontiers in Cellular and Infection Microbiology. 11. Article 632647. https://doi.org/10.3389/fcimb.2021.632647.

Cytokine and haptoglobin profiles from shipping through sickness and recovery in metaphylaxis- or un-treated cattle - (Peer Reviewed Journal)
Chitko-McKown, C.G., Bennett, G.L., Kuehn, L.A., DeDonder, K.D., Apley, M.D., Harhay, G.P., Clawson, M.L., Workman, A.M., White, B.J., Larson, R.L., Capik, S.F., Lubbers, B.V. 2021. Cytokine and haptoglobin profiles from shipping through sickness and recovery in metaphylaxis- or un-treated cattle. Frontiers in Veterinary Science. 8. Article 611927. https://doi.org/10.3389/fvets.2021.611927.

Evaluation of CD109, PCP4, and SEMA3D genes for their association with Ovine Johne’s disease in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Hatipoglu, E., Kaptan, C., Baskurt, A., Yilmaz, O., Heaton, M.P. 2021. Evaluation of CD109, PCP4, and SEMA3D genes for their association with Ovine Johne’s disease in Turkish sheep. Animal Biotechnology. Article 1887880. https://doi.org/10.1080/10495398.2021.1887880.

Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep - (Pre-print Publication)
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Ün, C., Heaton, M.P. 2021. Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep. Research Square. pg. 1-17. https://doi.org/10.21203/rs.3.rs-146053/v1.

Development of a multiplex real-time PCR assay for predicting macrolide and tetracycline resistance associated with bacterial pathogens of bovine respiratory disease - (Peer Reviewed Journal)
Dutta, E., Loy, J.D., Deal, C.A., Wynn, E.L., Clawson, M.L., Clarke, J., Wang, B. 2021. Development of a multiplex real-time PCR assay for predicting macrolide and tetracycline resistance associated with bacterial pathogens of bovine respiratory disease. Pathogens. 10:64. https://doi.org/10.3390/pathogens10010064.

A reference genome assembly of American bison, Bison bison bison - (Peer Reviewed Journal)
Oppenheimer, J., Rosen, B.D., Heaton, M.P., Vander Ley, B.L., Shafer, W.R., Schuetze, F.T., Stroud, B., Kuehn, L.A., McClure, J.C., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Bickhart, D.M., Davenport, K.M., Kuhn, K.L., Green, R.E., Shapiro, B., Smith, T.P.L. 2021. A reference genome assembly of American bison, Bison bison bison. Journal of Heredity. 112(2):174-183. https://doi.org/10.1093/jhered/esab003.

A reference genome assembly of Simmental cattle, Bos taurus taurus - (Peer Reviewed Journal)
Heaton, M.P., Smith, T.P.L., Bickhart, D.M., Vander Ley, B.L., Kuehn, L.A., Oppenheimer, J., Shafer, W.R., Schuetze, F.T., Stroud, B., McClure, J.C., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Davenport, K.M., Kuhn, K.L., Green, R.E., Shapiro, B., Rosen, B.D. 2021. A reference genome assembly of Simmental cattle, Bos taurus taurus. Journal of Heredity. 112(2):184-191. https://doi.org/10.1093/jhered/esab002.

Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns - (Rapid Release Publication)
Dickey, A.M., Smith, T.P.L., Clawson, M.L., Heaton, M.P., Workman, A.M. 2020. Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns. F1000Research. 9:1449. https://doi.org/10.12688/f1000research.27898.1.

Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression - (Peer Reviewed Journal)
Kalbfleisch, T., Petersen, J.L., Tait, R.G., Qiu, J., Basnayake, V., Hackett, P.H., Heaton, M.P. 2020. Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression. F1000Research. 9:1096. https://doi.org/10.12688/f1000research.25803.1.

Differences between predicted outer membrane proteins of genotype 1 and 2 Mannheimia haemolytica - (Peer Reviewed Journal)
Clawson, M.L., Schuller, G., Dickey, A.M., Bono, J.L., Murray, R.W., Sweeney, M.T., Apley, M.D., DeDonder, K.D., Capik, S.F., Larson, R.L., Lubbers, B.V., White, B.J., Blom, J., Chitko-McKown, C.G., Brichta-Harhay, D.M., Smith, T.P.L. 2020. Differences between predicted outer membrane proteins of genotype 1 and 2 Mannheimia haemolytica. BMC Microbiology. 20:250. https://doi.org/10.1186/s12866-020-01932-2.

An innate host-associated antimicrobial agent impacts key inflammatory biomarker expression and production - (Abstract Only)
Dawes, M.E., Xie, C., Chitko-McKown, C.G. 2020. An innate host-associated antimicrobial agent impacts key inflammatory biomarker expression and production [abstract]. In: Poster session of SoCal's Virtual Immunology, Stemcell Technologies. Zoom meeting Aug. 14, 2020. World Wide Web. Poster session.

Host transcriptional response to persistent infection with a live-attenuated porcine reproductive and respiratory syndrome virus strain - (Peer Reviewed Journal)
Chaudhari, J., Liew, C., Workman, A.M., Riethoven, J.M., Steffen, D., Sillman, S., Vu, H.L.X. 2020. Host transcriptional response to persistent infection with a live-attenuated porcine reproductive and respiratory syndrome virus strain. Viruses. 12(8):817. https://doi.org/10.3390/v12080817.

Rapid differentiation of Moraxella bovoculi genotypes 1 and 2 using MALDI-TOF mass spectrometry profiles - (Peer Reviewed Journal)
Hille, M., Dickey, A.M., Robbins, K., Clawson, M.L., Loy, J.D. 2020. Rapid differentiation of Moraxella bovoculi genotypes 1 and 2 using MALDI-TOF mass spectrometry profiles. Journal of Microbiological Methods. 173:105942. https://doi.org/10.1016/j.mimet.2020.105942.

Resistance to bovine viral diarrhea virus (BVDV) infection in the bovine kidney CRIB cell line is not due to PTPN12, GRID2, or RABGAP1L mutations - (Abstract Only)
Workman, A.M., Heaton, M.P., Webster, D.A., Kalbfleisch, T.S., Smith, T.P., Carlson, D.F., Sonstegard, T.S. 2020. Resistance to bovine viral diarrhea virus (BVDV) infection in the bovine kidney CRIB cell line is not due to PTPN12, GRID2, or RABGAP1L mutations [abstract]. In: Proceedings of American Society for Virology Meeting, June 13-17, 2020, Fort Collins, Colorado. Poster No. P37-1.

Identification of pan and core genomes of Moraxella bovis - (Abstract Only)
Clawson, M.L., Schuller, G., Dickey, A.M., Hille, M.M., Wynn, E.L., Loy, J.D. 2020. Identification of pan and core genomes of Moraxella bovis [abstract]. American Society for Microbiology Microbe, June 18-22, 2020, Chicago, Illinois. Poster No. 6697.

Differentiation of Mannheimia haemolytica genotypes 1 and 2 by visible phenotypic characteristics on solid media - (Abstract Only)
Wynn, E.L., Schuller, G., Loy, J.D., Workman, A.M., McDaneld, T.G., Clawson, M.L. 2020. Differentiation of Mannheimia haemolytica genotypes 1 and 2 by visible phenotypic characteristics on solid media [abstract]. American Society for Microbiology Microbe, June 18-22, 2020, Chicago, Illinois. Poster No. 6696.

Differentiation of Mannheimia haemolytica genotype 1 and 2 strains by visible phenotypic characteristics on solid media - (Peer Reviewed Journal)
Wynn, E.L., Schuller, G., Loy, J.D., Workman, A.M., McDaneld, T.G., Clawson, M.L. 2020. Differentiation of Mannheimia haemolytica genotype 1 and 2 strains by visible phenotypic characteristics on solid media. Journal of Microbiological Methods. 171. Article 105877. https://doi.org/10.1016/j.mimet.2020.105877.

Mitochondrial DNA repair in an Arabidopsis thaliana uracil N-glycosylase mutant - (Peer Reviewed Journal)
Wynn, E.L., Purfeerst, E., Christensen, A.C. 2020. Mitochondrial DNA repair in an Arabidopsis thaliana uracil N-glycosylase mutant. Plants. 9(2):261. https://doi.org/10.3390/plants9020261.

Development of a multiplex assay for the bovine inflammatory cytokines IL-1ß, IL-6, and TNF-a - (Abstract Only)
Chitko-McKown, C.G., Bierman, S.L. 2020. Development of a multiplex assay for the bovine inflammatory cytokines IL-1ß, IL-6, and TNF-a [abstract]. Immunology. 204 (Supplement 1):92.41.

Upregulation of the type I interferon pathway in feedlot cattle persistently infected with bovine viral diarrhea virus - (Peer Reviewed Journal)
Nilson, S.M., Workman, A.M., Sjeklocha, D., Brodersen, B., Grotelueschen, D.M., Petersen, J.L. 2020. Upregulation of the type I interferon pathway in feedlot cattle persistently infected with bovine viral diarrhea virus. Virus Research. 278:197862. https://doi.org/10.1016/j.virusres.2020.197862.

Detection of bovine viral diarrhea virus in stable flies following consumption of blood from persistently infected cattle - (Peer Reviewed Journal)
Carlson, J.M., Vander Ley, B.L., Lee, S.I., Grotelueschen, D.M., Walz, P.H., Workman, A.M., Heaton, M.P., Boxler, D.J. 2020. Detection of bovine viral diarrhea virus in stable flies following consumption of blood from persistently infected cattle. Journal of Veterinary Diagnostic Investigation. 32(1):108-111. https://doi.org/10.1177/1040638719898688.

Association of ARRDC3 and NF1A genes with bovine congestive heart failure - (Abstract Only)
Heaton, M.P., Harhay, G.P., Bassett, A.S., Clark, H.J., Carlson, J.M., Smith, H.R., Pelster, M.C., Workman, A.M., Grotelueschen, D.M., Vander Ley, B.L. 2020. Association of ARRDC3 and NF1A genes with bovine congestive heart failure. In: Plant and Animal Genome Conference Proceedings, January 11-15, 2020, San Diego, California. PE0326.

The respiratory microbiome is altered in dairy calves fed milk-replacer with added probiotics - (Abstract Only)
Chitko-McKown, C.G., McDaneld, T.G., Eicher, S.D., Kritchevsky, J.E., Bryan, K.A. 2019. The respiratory microbiome is altered in dairy calves fed milk-replacer with added probiotics [abstract]. Conference of Research Workers in Animal Diseases, November 2-5, 2019, Chicago, Illinois. Abstract #237.

Progress report on a plains bison-Simmental interspecies cross for genome assembly by trio binning - (Other)
Heaton, M.P., Kuehn, L.A., Vander Ley, B.L., Clark, H.J., Shafer, W., Schuetze, F., Stroud, B., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Rosen, B.D., Bickhart, D.M., Oppenheimer, J., Shapiro, B., Green, R.E., Smith, T.P. 2019. Progress report on a plains bison-Simmental interspecies cross for genome assembly by trio binning [abstract]. Fall Focus 2019, Manhattan, Kansas, August 25-27, 2019. Available: https://simmental.org.

Evaluation of EPAS1 variants for association with bovine congestive heart failure - (Peer Reviewed Journal)
Heaton, M.P., Bassett, A.S., Whitman, K.J., Krafsur, G.M., Lee, S., Carlson, J.M., Clark, H.J., Smith, H.R., Pelster, M.C., Basnayake, V., Grotelueschen, D.M., Vander Ley, B.L. 2019. Evaluation of EPAS1 variants for association with bovine congestive heart failure. F1000Research. 8:1189. https://doi.org/10.12688/f1000research.19951.1.

Association of TMEM154 variants with visna/maedi virus infection in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Keles, M., Aymaz, R., Sevim, S., Sezenler, T., Onaldi, A.T., Kaptan, C., Baskurt, A., Koncagul, S., Oner, Y., Ozturk, E., Iriadam, M., Un, C., Heaton, M.P. 2019. Association of TMEM154 variants with visna/maedi virus infection in Turkish sheep. Small Ruminant Research. 177:61-67. https://doi.org/10.1016/j.smallrumres.2019.06.006.

Longitudinal study of humoral immunity to bovine coronavirus, virus shedding, and treatment for bovine respiratory disease in pre-weaned beef calves - (Peer Reviewed Journal)
Workman, A.M., Kuehn, L.A., McDaneld, T.G., Clawson, M.L., Loy, J.D. 2019. Longitudinal study of humoral immunity to bovine coronavirus, virus shedding, and treatment for bovine respiratory disease in pre-weaned beef calves. BioMed Central (BMC) Veterinary Research. 15:161. https://doi.org/10.1186/s12917-019-1887-8.

Impact of CD46 knockout on bovine viral diarrhea virus (BVDV) replication in Madin-Darby bovine kidney cells - (Abstract Only)
Workman, A.M., Webster, D.A., Carlson, D.F., Heaton, M.P., Falkenberg, S.M., Neill, J.D., Sonstegard, T.S. 2019. Impact of CD46 knockout on bovine viral diarrhea virus (BVDV) replication in Madin-Darby bovine kidney cells [abstract]. In: Proceedings of American Society for Virology Meeting, July 20-24, 2019, Minneapolis, Minnesota. Poster No. P17-16.

A host-associated antimicrobial agent exhibits both immunoprotective and immunotherapeutic effects - (Abstract Only)

A computational method to quantify the effects of slipped strand mispairing on bacterial tetranucleotide repeats - (Peer Reviewed Journal)
Harhay, G.P., Harhay, D.M., Bono, J.L., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L., Smith, T.P.L. 2019. A computational method to quantify the effects of slipped strand mispairing on bacterial tetranucleotide repeats. Nature Scientific Reports. 9:18087. https://doi.org/10.1038/s41598-019-53866-z.

A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin - (Peer Reviewed Journal)
Workman, A.M., Chitko-McKown, C.G., Smith, T.P.L., Bennett, G.L., Kalbfleisch, T.S., Basnayake, V., Heaton, M.P. 2018. A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin. F1000Research. 7:1985. https://doi.org/10.12688/f1000research.17187.1.

Whole genome sequencing of Moraxella bovoculi reveals high genetic diversity and evidence for interspecies recombination at multiple loci - (Peer Reviewed Journal)
Dickey, A.M., Schuller, G., Loy, J.D., Clawson, M.L. 2018. Whole genome sequencing of Moraxella bovoculi reveals high genetic diversity and evidence for interspecies recombination at multiple loci. PLoS One. 13(12):e0209113. https://doi.org/10.1371/journal.pone.0209113.

Evaluation of EPAS1 variants for association with bovine congestive heart failure - (Abstract Only)
Heaton, M.P., Bassett, A.S., Whitman, K.J., Krafsur, G.M., Lee, S.I., Carlson, J.M., Clark, H.J., Smith, H.R., Pelster, M.C., Basnayake, V., Grotelueschen, D.M., Vander Ley, B.L. 2019. Evaluation of EPAS1 variants for association with bovine congestive heart failure [abstract]. International Plant & Animal Genome XXVII Conference, January 12-16, 2019, San Diego, California. Abstract PO0365. Available: https://plan.core-apps.com/pag_2019/abstracts

A novel host-associated non-traditional antimicrobial agent, exhibits immune regulatory function - (Abstract Only)
Dawes, M.E., Xie, C., Chitko-McKown, C.G. 2018. A novel host-associated non-traditional antimicrobial agent, exhibits immune regulatory function [abstract]. Conference of Research Workers in Animal Diseases, December 2-4, 2018, Chicago, Illinois. Abstract #189.

First complete genome sequence of a genotype A2, subgroup 4 small ruminant lentivirus - (Peer Reviewed Journal)
Workman, A.M., Clawson, M.L., Heaton, M.P., Dickey, A.M. 2018. First complete genome sequence of a genotype A2, subgroup 4 small ruminant lentivirus. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. 7(19):e01337-18. https://doi.org/10.1128/MRA.01337-18.

Correlates of cross-protective immunity to porcine reproductive and respiratory syndrome virus - (Abstract Only)
Vu, H.L., Sun, H., Workman, A.M., Steffen, D., Osorio, F. 2018. Correlates of cross-protective immunity to porcine reproductive and respiratory syndrome virus [abstract]. Conference of Research Workers in Animal Diseases Conference, December 1-4, 2018, Chicago, Illinois. Abstract #10. Available: https://crwad.org/proceedings-archive/

Structure-guided identification of a nonhuman morbillivirus with zoonotic potential - (Peer Reviewed Journal)
Abdullah, N., Kelly, J.T., Graham, S.C., Birch, J., Goncalves-Carneiro, D., Mitchell, T., Thompson, R.N., Lythgoe, K.A., Logan, N., Hosie, M.J., Bavro, V.N., Willett, B.J., Heaton, M.P., Bailey, D. 2018. Structure-guided identification of a nonhuman morbillivirus with zoonotic potential. Journal of Virology. 92(23):e01248-18. https://doi.org/10.1128/jvi.01248-18.

Moving beyond the MIC: Evaluation of a novel multiplex real time PCR assay for detection of antimicrobial resistance genes in clinical bovine respiratory disease samples - (Abstract Only)
Loy, J.D., Payne, J., Deal, C., Dutta, E., Bulut, E., Clawson, M.L., Wang, B. 2018. Moving beyond the MIC: Evaluation of a novel multiplex real time PCR assay for detection of antimicrobial resistance genes in clinical bovine respiratory disease samples [abstract]. In: Proceedings of the American Association of Veterinary Laboratory Diagnosticians, October 18-22, 2018, Kansas City, Missouri. p. 7.

Closed genome sequences and antibiograms of 16 pasteurella multocida isolates from bovine respiratory disease complex cases and apparently healthy controls - (Peer Reviewed Journal)
Harhay, G.P., Harhay, D.M., Bono, J.L., Smith, T.P.L., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L. 2018. Closed genome sequences and antibiograms of 16 pasteurella multocida isolates from bovine respiratory disease complex cases and apparently healthy controls. Microbiology Resource Announcements. 7(11):e00976-18. https://doi.org/10.1128/MRA.00976-18.

In search of a genetic cause for heart failure in beef cattle - (Abstract Only)
Heaton, M.P. 2018. In search of a genetic cause for heart failure in beef cattle. [abstract online]. Available: http://www.vbms.unl.edu.

Complete genome sequence of Moraxella bovis strain Epp63, an etiologic agent of infectious bovine keratoconjunctivitis - (Peer Reviewed Journal)
Loy, J.D., Dickey, A.M., Clawson, M.L. 2018. Complete genome sequence of Moraxella bovis strain Epp63, an etiologic agent of infectious bovine keratoconjunctivitis. Microbiology Resource Announcements. 7(8):1-2. https://doi.org/10.1128/MRA01004.18.

Cardiopulmonary remodeling in fattened beef cattle: A naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease - (Peer Reviewed Journal)
Krafsur, G.M., Neary, J.M., Garry, F., Holt, T., Gould, D.H., Mason, G.L., Thomas, M.G., Enns, R.M., Tuder, R.M., Heaton, M.P., Brown, R.D., Stenmark, K.R. 2019. Cardiopulmonary remodeling in fattened beef cattle: A naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease. Pulmonary Circulation. 9(1):1-13. https://doi.org/10.1177/2045894018796804.

Development of a multiplex real-time PCR assay using two thermocycling platforms for detection of major bacterial pathogens associated with bovine respiratory disease complex from clinical samples - (Peer Reviewed Journal)
Loy, J.D., Leger, L., Workman, A.M., Clawson, M.L., Bulut, E., Wang, B. 2018. Development of a multiplex real-time PCR assay using two thermocycling platforms for detection of major bacterial pathogens associated with bovine respiratory disease complex from clinical samples. Journal of Veterinary Diagnostic Investigation. 30(6):837-847. https://doi.org/10.1177/1040638718800170.

Genomic signatures of a Mannheimia haemolytica lineage associated with bovine respiratory disease - (Abstract Only)
Clawson, M.L., Schuller, G., Dickey, A.M., Murray, R.W., Sweeney, M.T., Apley, M.D., DeDonder, K.D., Capik, S.F., Larson, R.L., Lubbers, B.V., White, B.J., Blom, J., Brichta-Harhay, D.M., Smith, T.P. 2018. Genomic signatures of a Mannheimia haemolytica lineage associated with bovine respiratory disease [abstract]. Society for Molecular Biology & Evolution General Meeting. Abstract POA-070:44. Available: http://evolgen.biol.se.tmu.ac.jp/SMBE2018/POA.pdf

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of Moraxella bovoculi and Moraxella bovis isolates from cattle - (Peer Reviewed Journal)
Robbins, K., Dickey, A.M., Clawson, M.L., Loy, J.D. 2018. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of Moraxella bovoculi and Moraxella bovis isolates from cattle. Journal of Veterinary Diagnostic Investigation. p. 1-4. Available: jvdi.sagepub.com. https://doi.org/10.1177/1040638718789725.

A SNP resource for studying North American moose - (Peer Reviewed Journal)
Kalbfleisch, T.S., Murdoch, B.M., Smith, T.P.L., Murdoch, J.D., Heaton, M.P., Mckay, S.D. 2018. A SNP resource for studying North American moose. F1000Research. 7(40):1-17. https://doi.org/10.12688/f1000research.13501.1.

The Wnt signaling pathway is differentially expressed during the bovine herpesvirus 1 latency-reactivation cycle: evidence that two protein kinases associated with neuronal survival (Akt3 and bone morphogenetic protein.... - (Peer Reviewed Journal)
Workman, A.M., Zhu, L., Keel, B.N., Smith, T.P.L., Jones, C. 2018. The Wnt signaling pathway is differentially expressed during the bovine herpesvirus 1 latency-reactivation cycle: evidence that two protein kinases associated with neuronal survival (Akt3 and bone morphogenetic protein receptor 2) are expressed at higher levels during latency. Journal of Virology. 92:e01937-17. https//doi.org/10.1128/JVI.01937-17.

Using cattle and sheep reference assemblies to develop genomic resources for North American moose - (Abstract Only)
Heaton, M.P. 2018. Using cattle and sheep reference assemblies to develop genomic resources for North American moose [abstract]. International Plant & Animal Genome XXVI Conference, January 13-17, 2018, San Diego, California. Abstract W153. Available: https://plan.core-apps.com/pag_2018/abstracts

Development of a broadly protective modified-live virus vaccine candidate against porcine reproductive and respiratory syndrome virus - (Peer Reviewed Journal)
Sun, H., Workman, A., Osorio, F.A., Steffen, D., Vu, H.L.X. 2017. Development of a broadly protective modified-live virus vaccine candidate against porcine reproductive and respiratory syndrome virus. Vaccine. 36:66-73. https://doi.org/10.1016/j.vaccine.2017.11.028.

Development and characterization of a bovine monocyte-derived macrophage cell line - (Abstract Only)
Chitko-Mckown, C.G., Bartens, M.C., Gibson, A.J., Holder, A., Vats, A., Brown, E., Kolakowski, J., Workman, A.M., Heaton, M.P., Kalbfleisch, T.S., Werling, D. 2021. Development and characterization of a bovine monocyte-derived macrophage cell line [abstract]. Conference of Research Workers in Animal Diseases Conference, December 3-5,2017, Chicago, Illinois. Abstract #141. Available: https://crwad.org/proceedings-archive/

Molecular and epidemiological characterization of a respiratory disease outbreak in pre-weaned beef calves associated with bovine coronavirus - (Abstract Only)
Workman, A.M., McDaneld, T.G., Kuehn, L.A., Clawson, M.L., Loy, J.D. 2017. Molecular and epidemiological characterization of a respiratory disease outbreak in pre-weaned beef calves associated with bovine coronavirus. Conference of Research Workers in Animal Diseases Conference Proceedings, December 3-5, 2017, Chicago, Illinois. Abstract #203. Available: https://crwad.org/crwad-2017/

Closed genome sequences of seven histophilus somni isolates from beef calves with bovine respiratory disease complex - (Peer Reviewed Journal)
Harhay, G.P., Harhay, D.M., Bono, J.L., Smith, T.P.L., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L. 2017. Closed genome sequences of seven histophilus somni isolates from beef calves with bovine respiratory disease complex. Genome Announcements. 5(40):e01099-17. https://doi.org/10.1128/genomeA.01099-17.

Phenotyping and susceptibility of established porcine cells lines to African swine fever virus infection and viral production - (Peer Reviewed Journal)
Sanchez, E.G., Riera, E., Nogal, M., Gallardo, C., Fernandez, P., Bello-Morales, R., Lopez-Guerrero, J., Chitko-McKown, C.G., Richt, J.A., Revilla, Y. 2017. Phenotyping and susceptibility of established porcine cells lines to African swine fever virus infection and viral production. Scientific Reports. 7:10369. https://doi.org/10.1038/s41598-017-09948-x.

Using sheep genomes from diverse U.S. breeds to identify missense variants in genes affecting fecundity - (Peer Reviewed Journal)
Heaton, M.P., Smith, T.P.L., Freking, B.A., Workman, A.M., Bennett, G.L., Carnahan, J.K., Kalbfleisch, T.S. 2017. Using sheep genomes from diverse U.S. breeds to identify missense variants in genes affecting fecundity. F1000Research. 6:1303. https://doi.org/10.12688/f1000research.12216.1.

Closed genomes and phenotypes of seven Histophilus somni isolates from beef calves with bovine respiratory disease complex - (Abstract Only)
Harhay, G.P., Harhay, D.M., Bono, J.L., Smith, T.P., Heaton, M.P., Clawson, M.L., Chitko-McKown, C.G., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L. 2017. Closed genomes and phenotypes of seven Histophilus somni isolates from beef calves with bovine respiratory disease complex [Abstract]. American Society for Microbiology Microbe Meeting, June 1-5, 2017, New Orleans, LA. Poster #Sunday-869.

Complete genome sequences of two genotype A2 small ruminant lentiviruses isolated from infected U.S. sheep - (Peer Reviewed Journal)
Workman, A.M., Dickey, A.M., Heaton, M.P., Clawson, M.L., Smith, T.P.L. 2017. Complete genome sequences of two genotype A2 small ruminant lentiviruses isolated from infected U.S. sheep. Genome Announcements. 5(13):e00109-17.