Submitted to: United States Animal Health Association Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 10/30/1995
Publication Date: N/A
Technical Abstract: This manuscript reviews the biosafety and vaccine characteristics of the Brucella abortus strain RB51 (SRB51) cattle vaccine. When administered to cattle, SRB51 is stable, cleared from draining lymph nodes by 12 weeks, and provides high levels of protection against experimental infection with virulent strains of B. abortus. When compared to the current cattle vaccine, B. abortus strain 19, SRB51 is superior as it does not interfere with the serologic identification of infected animals. Use of SRB51 in field studies with pregnant cattle has failed to demonstrate deleterious clinical effects such as abortion or arthritis.