Skip to main content
ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » People & Locations » Steven Olsen

Steven C Olsen
Infectious Bacterial Diseases Research
Supervisory Veterinary Medical Officer

Phone: (515) 337-7230
Fax: (515) 337-7148
Room 2S508

1920 DAYTON AVE
AMES, IA 50010
Projects
Pathogenesis and Development of Improved Diagnostic and Control Strategies for Brucellosis in Livestock and Wildlife
In-House Appropriated (D)
  Accession Number: 432153

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Influence of species of negative control sera on results of a brucellosis fluorescence polarization assay - (Peer Reviewed Journal)
Enhancing the detection of Brucella-specific CD4+ T cell responses in cattle via in vitro antigenic expansion and restimulation Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Schaut, R.G., Olsen, S.C. 2020. Enhancing the detection of Brucella-specific CD4+ T cell responses in cattle via in vitro antigenic expansion and restimulation. Frontiers in Immunology. 11:1944. https://doi.org/10.3389/fimmu.2020.01944.
Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Crawford, L.S., Kanipe, C., Palmer, M.V., Olsen, S.C. 2020. Case report: fading elk syndrome in a herd of captive elk (Cervus elaphus) in the North American midwest. Frontiers in Veterinary Science. 7:497. https://doi.org/10.3389/fvets.2020.00497.
Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms Reprint Icon - (Peer Reviewed Journal)
Wilson-Welder, J.H., Boggiatto, P.M., Nally, J.E., Wafa, E.I., Alt, D.P., Hornsby, R.L., Frank, A.T., Jones, D.E., Olsen, S.C., Bowden, N.B., Salem, A.K. 2020. Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms. Vaccine. 38(18):3464-3473. https://doi.org/10.1016/j.vaccine.2020.02.086.
Characterization of the RB51 genome sequence in the context of vaccine properties Reprint Icon - (Peer Reviewed Journal)
Bricker, B.J., Goonesekere, N., Bayles, D.O., Alt, D.P., Olsen, S.C., Vrentas, C.E. 2020. Genome report-a genome sequence analysis of the RB51 strain of Brucella abortus in the context of its vaccine properties. G3, Genes/Genomes/Genetics. 10(4):1175-1181. https://doi.org/10.1534/g3.119.400964.
Tulathromycin treatment does not affect bacterial dissemination or clearance of Brucella melitensis 16M following experimental infection of goats Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Olsen, S.C. 2019. Tulathromycin treatment does not affect bacterial dissemination or clearance of Brucella melitensis 16M following experimental infection of goats. PLoS One. 14(12):e0226242. https://doi.org/10.1371/journal.pone.0226242.
Characterization of the NLRP1 inflammasome response in bovine species Reprint Icon - (Peer Reviewed Journal)
Vrentas, C.E., Boggiatto, P.M., Olsen, S.C., Leppla, S.H., Moayeri, M. 2020. Characterization of the NLRP1 inflammasome response in bovine species. Innate Immunity. 26(4):301-311. https://doi.org/10.1177/1753425919886649.
Sustained antigen release, polyanhydride-based vaccine platform for immunixation against bovine brucellosis Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Schaut, R.G., Kanipe, C., Kelly, S.M., Narasimhan, B., Jones, D.E., Olsen, S.C. 2019. Sustained antigen release, polyanhydride-based vaccine platform for immunixation against bovine brucellosis. Heliyon. 5(8). https://doi.org/10.1016/j.heliyon.2019.e02370.
Coincidence cloning recovery of Brucella melitensis RNA from goat tissues: advancing the in vivo analysis of pathogen gene expression in brucellosis Reprint Icon - (Peer Reviewed Journal)
Boggiatto, P.M., Vrentas, C.E., Fitzsimmons, D.J., Bayles, D.O., Alt, D.P., Olsen, S.C. 2018. Coincidence cloning recovery of Brucella melitensis RNA from goat tissues: advancing the in vivo analysis of pathogen gene expression in brucellosis. BioMed Central (BMC) Molecular Biology. 19:10. https://doi.org/10.1186/s12867-018-0111-x.
Relative virulence in bison and cattle of bison-associated genotypes of mycoplasma bovis Reprint Icon - (Peer Reviewed Journal)
Register, K.B., Olsen, S.C., Sacco, R.E., Ridpath, J., Falkenberg, S., Briggs, R., Kanipe, C., Madison, R. 2018. Relative virulence in bison and cattle of bison-associated genotypes of Mycoplasma bovis. Veterinary Microbiology. 222:55-63. https://doi.org/10.1016/j.vetmic.2018.06.020.
Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species Reprint Icon ()
Vrentas, C.E., Schaut, R.G., Boggiatto, P.M., Olsen, S.C., Sutterwala, F.G., Moayeri, M. 2018. Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species. Veterinary Immunology and Immunopathology. 201:49-56. https://doi.org/10.1016/j.vetimm.2018.05.008.
Short communication: Lymphocyte proliferative responses in cattle naturally infected with digital dermatitis consists of CD8+ and gamma delta T cells but lack CD4+ T cells Reprint Icon - (Peer Reviewed Journal)
Wilson-Welder, J.H., Nally, J.E., Alt, D.P., Humphrey, S.B., Olsen, S.C. 2018. Short communication: Lymphocyte proliferative responses in cattle naturally infected with digital dermatitis consists of CD8plus and gamma delta T cells but lack CD4plus T cells. Journal of Dairy Science. 101(9):8301-8307. https://doi.org/10.3168/jds.2017-13913.
Collection and processing of lymph nodes from large animals for RNA analysis: preparing for lymph node transcriptomic studies of large animal species Reprint Icon - (Peer Reviewed Journal)
Vrentas, C.E., Boggiatto, P.M., Schaut, R.G., Olsen, S.C. 2018. Collection and processing of lymph nodes from large animals for RNA analysis: preparing for lymph node transcriptomic studies of large animal species. Journal of Visualized Experiments. 135:e57195. doi:10.3791/57195.
Biosafety concerns related to Brucella and its potential use as a bioweapon Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., White, D.M., McNunn, T.B. 2018. Biosafety concerns related to Brucella and its potential use as a bioweapon. Applied Biosafety. 23(2)77-90. https://doi.org/10.1177/1535676018771983.
Inactivation of virulent Brucella species in culture and animal samples Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., Boggiatto, P.M., Vrentas, C.E. 2017. Inactivation of virulent Brucella species in culture and animal samples. Applied Biosafety. 22(4):145-151. https://doi.org/10.1177/1535676017734202.
Identification of Brucella spp. in feral swine (Sus scrofa) at abattoirs in Texas, USA - (Peer Reviewed Journal)
Pederson, K., Bauer, N., Gidlewski, T., Olsen, S.C., Arenas, A., Henry, A., Sibley, T., Nolte, D. 2017. Identification of Brucella spp. in feral swine (Sus scrofa) at abattoirs in Texas, USA. Zoonoses and Public Health. doi: 10.1111/zph.12359.
Immunogenicity and efficacy of a rough Brucella suis vaccine delivered orally or parenterally to feral swine - (Peer Reviewed Journal)
Olsen, S.C., Wilson-Welder, J.H., Nol, P., Rhyan, J., Srirangathan, N. 2017. Immunogenicity and efficacy of a rough Brucella suis vaccine delivered orally or parenterally to feral swine. International Journal of Vaccine Research. 2(1): 6.
Swine Brucellosis: Current Perspectives - (Peer Reviewed Journal)
Interaction of bovine peripheral blood polymorphonuclear cells and Leptospira species; innate responses in the natural bovine reservoir host. - (Peer Reviewed Journal)
Wilson-Welder, J.H., Frank, A.T., Hornsby, R.L., Olsen, S.C., Alt, D.P. 2016. Interaction of bovine peripheral blood polymorphonuclear cells and Leptospira species; innate responses in the natural bovine reservoir host. Frontiers in Microbiology. 7:1110.
Vaccination of elk (Cervus canadensis) with Brucella abortus strain RB51 overexpressing superoxide dismutase and glycosyltransferase genes does not induce adequate protection against experimental brucella abortus challenge - (Peer Reviewed Journal)
Nol, P., Olsen, S.C., Rhyan, J.C., Sriranganathan, N., McCollum, M.P., Hennager, S.G., Garner, A., Sprino, P.J., Berrier, R.J., Elzer, P., Boyle, S.M., Salman, M.D. 2016. Vaccination of elk (Cervus canadensis) with Brucella abortus strain RB51 overexpressing superoxide dismutase and glycosyltransferase genes does not induce adequate protection against experimental brucella abortus challenge. Frontiers in Cellular and Infection Microbiology. 6:10. doi: 10.3389/fcimb.2016.00010.
Live RB51 vaccine lyophilized hydrogel formulations with increased shelf life for practical ballistic delivery - (Peer Reviewed Journal)
Falconer, J., Christie, R.J., Kaiser, E.J., Olsen, S.C., Grainger, D.W. 2016. Live RB51 vaccine lyophilized hydrogel formulations with increased shelf life for practical ballistic delivery. International Journal of Pharmaceutics. 498(1-2):187-94. doi:10.1016/j.iipharm.2015.12.040.
Knowledge of Brucella as a food-borne pathogen ()
Relative virulence in bison and cattle of bison-associated genotypes of Mycoplasma bovis - (Abstract Only)
Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51 Reprint Icon - (Peer Reviewed Journal)
Olsen, S.C., McGill, J.L., Sacco, R.E., Hennager, S.G. 2015. Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51. Clinical and Vaccine Immunology. 22(4):440-447. doi: 10.1128/CVI.00746-14.
In vitro bactericidal activity of aminoglycosides, including the next-generation drug plazomicin, against Brucella spp. - (Peer Reviewed Journal)
The quest for a true One Health perspective of brucellosis - (Peer Reviewed Journal)
Godfroid, J., Debolle, X., Roop, R.M., Ocallaghan, D., Tsolis, R., Baldwin, C., Santos, R.L., Mcgiven, J., Olsen, S.C., Nymo, I., Larsen, A., Dahouk, S.A., Letesson, J.J. 2014. The quest for a true One Health perspective of brucellosis. World Organization for Animal Health Scientific and Technical Review. 33(2):521-538.
Introduction to working safely with large animals in containment - (Peer Reviewed Journal)
Johnson, B., Olsen, S.C. 2014. Introduction to working safely with large animals in containment. Applied Biosafety. 19(2):98-100.
Advancement of knowledge of Brucella over the past 50 years - (Peer Reviewed Journal)
Olsen, S.C., Palmer, M.V. 2014. Advancement of knowledge of Brucella over the past 50 years. Veterinary Pathology. DOI: 10.1177/0300985814540545.
Evaluation of enzyme-linked immunosorbent assays for detection of Mycoplasma bovis-Specific antibody in bison sera Reprint Icon - (Peer Reviewed Journal)
Register, K.B., Sacco, R.E., Olsen, S.C. 2013. Evaluation of enzyme-linked immunosorbent assays for detection of Mycoplasma bovis-Specific antibody in bison sera. Clinical and Vaccine Immunology. 20(9):1405-1409 DOI: 10.1128/CVI.00409-13.
Mycoplasma bovis research update Reprint Icon ()
Register, K.B., Sacco, R.E., Olsen, S.C. 2013. Mycoplasma bovis research update. Trade Journal Publication. Available: http://www.bisoncentral.com.
Immuogenicity and safety of a natural rough mutant of Brucella suis as a vaccine for swine Reprint Icon - (Peer Reviewed Journal)
Stoffregen, W.C., Johnson, C.S., Olsen, S.C. 2013. Immunogenicity and safety of a natural rough mutant of Brucella suis as a vaccine for swine. Research in Veterinary Science. 95(2013):251-258.
High-impact animal health research conducted at the USDA's National Animal Disease Center Reprint Icon - (Peer Reviewed Journal)
Bannantine, J.P., Olsen, S.C., Kehrli Jr, M.E., Stanton, T.B., Casas, E., Whipple, D.L., Zuelke, K.A. 2013. High-impact animal health research conducted at the USDA's National Animal Disease Center. Veterinary Microbiology. 165(2013):224-233 DOI: 10.1016/j.vetmic.2013.04.010.
Biosafety considerations for in vivo work with risk group 3 pathogens in large animals and wildlife in North America - (Peer Reviewed Journal)
Olsen, S.C. 2013. Biosafety considerations for in vivo work with risk group 3 pathogens in large animals and wildlife in North America. Animal Health Research Reviews. 14(1):2-10.
Recent Developments in Livestock and Wildlife Brucellosis Vaccination - (Peer Reviewed Journal)
Olsen, S.C. 2013. Recent developments in livestock and wildlife brucellosis vaccination. World Organization for Animal Health Scientific and Technical Review. 32(1):207-217.
Letter to the Editor ()
Alt, D.P., Olsen, S.C., Bolin, C. 2012. Letters to the Editor. American Journal of Veterinary Research. 73(7):928-929.
Efficacy of dart or booster vaccination with strain RB51 in protecting bison against experimental Brucella abortus challenge - (Peer Reviewed Journal)
Olsen, S.C., Johnson, C.S. 2012. Efficacy of dart or booster vaccination with strain RB51 in protecting bison against experimental Brucella abortus challenge. Clinical and Vaccine Immunology. 19(6):886-890.
Immune responses and safety after dart or booster vaccination of bison with Brucella abortus strain RB51 - (Peer Reviewed Journal)
Olsen, S.C., Johnson, C.S. 2012. Immune responses and safety after dart or booster vaccination of bison with Brucella abortus strain RB51. Clinical and Vaccine Immunology. 19(5):642-648.
Brucella ()
Olsen, S.C., Bellaire, B., Roop II, R.M., Thoen, C.O. 2012. Brucella. In: Gyles, C.L., Prescott, J.F., Songer, J.G., Thoen, C.O., editors. Pathogenesis of Bacterial Infections in Animals. 4th edition. Hoboken, N.J.: Wiley-Blackwell. p. 429-441.
Working with biolevel 3 agents that interface across human, livestock and wildlife boundaries ()
Comparison of abortion and infection after experimental challenge of pregnant bison and cattle with Brucella abortus strain 2308 - (Peer Reviewed Journal)
Olsen, S.C., Johnson, C.S. 2011. Comparison of abortion and infection after experimental challenge of pregnant bison and cattle with Brucella abortus strain 2308. Clinical and Vaccine Immunology. 18(12):2075-2078.
Characterization of viral replication and the immune response in bison peripheral blood mononuclear cells following in vitro bovine viral diarrhea virus infection - (Abstract Only)
McGill, J.L., Schaut, R.G., Neill, J.D., Olsen, S.C., Ridpath, J.F., Sacco, R.E. 2011. Characterization of viral replication and the immune response in bison peripheral blood mononuclear cells following in vitro bovine viral diarrhea virus infection [abstract]. In: Proceedings of the U.S. Bovine Viral Diarrhea Virus Symposium, November 17-18, 2011, San Diego, California. p. 59.
Serological response to administration of Brucella abortus strain RB51 vaccine in beef and dairy heifers, using needle-free and standard needle-based injection systems - (Peer Reviewed Journal)
Pires, A.F., Hoar, B.R., Sischo, W.M., Olsen, S.C. 2011. Serological response to administration of Brucella abortus strain RB51 vaccine in beef and dairy heifers, using needle-free and standard needle-based injection systems. Bovine Practitioner Journal. 45(2):1-6.
Brucellosis ()
Olsen, S.C., Garin-Bastuji, B., Blasco, J.M., Nicola, A.M., Samartino, L. 2012. Brucellosis. In: Zimmerman, J.J., Karriker, L.A., Ramirez, A., Schwartz, K.J., Stevenson, G.W., editors. Diseases of Swine. 10th edition. Hoboken, N.J.: Wiley-Blackwell. p. 697-708.
A Live Vaccine from Brucella abortus Strain 82 for Control of Cattle Brucellosis in the Russian Federation - (Peer Reviewed Journal)
Ivanov, A.V., Salmakov, K.M., Olsen, S.C., Plumb, G.E. 2011. A live vaccine from Brucella abortus strain 82 for control of cattle brucellosis in the Russian Federation. Animal Health Research Reviews. 12(1):113-121.
A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization - (Peer Reviewed Journal)
Zuerner, R.L., Alt, D.P., Palmer, M.V., Thacker, T.C., Olsen, S.C. 2011. A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization. Clinical and Vaccine Immunology. 18(4):684-691.
Immune Responses and Protection against Experimental Brucella suis biovar 1 Challenge in Non-vaccinated or RB51-Vaccinated Cattle - (Peer Reviewed Journal)
Olsen, S.C., Hennager, S.G. 2010. Immune responses and protection against experimental Brucella suis biovar 1 challenge in non-vaccinated or B. abortus strain RB51-vaccinated cattle. Clinical and Vaccine Immunology. 17(12):1891-1895.
Brucellosis in the United States: Role and Significance of Wildlife Reservoirs - (Peer Reviewed Journal)
Olsen, S.C. 2010. Brucellosis in the United States: Role and significance of wildlife reservoirs. Vaccine. 28(S5):F73-F76.
Bovine Brucellosis - (Peer Reviewed Journal)
Olsen, S.C., Tatum, F.M. 2010. Bovine Brucellosis. Veterinary Clinics of North America. 26(1):15-27.
Economic and Zoonotic Implications of Brucella ()
Olsen, S.C., Samartino, L. 2009. Economic and Zoonotic Implications of Brucella. In: Nene, V., Kole, C., editors. Genome Mapping and Genomics in Animal-Associated Microbes. Heidelberg, Germany: Springer-Verlag. p. 4-7.
Brucella ()
Olsen, S.C., Bellaire, B.H., Roop Ii, R.M., Thoen, C.O. 2010. Brucella. In: Gyles, C.L., Prescott, J.F., Songer, J.G., Thoen, C.O., editors. Pathogenesis of Bacterial Infections in Animals. 4th edition. Singapore: Wiley-Blackwell. p. 429-441.
Immune responses and protection against experimental challenge after vaccination of bison with Brucella abortus strains RB51 or RB51 overexpressing superoxide dismutase and Glycosyltransferase genes - (Peer Reviewed Journal)
Olsen, S.C., Boyle, S.M., Schurig, G.G., Sriranganathan, N.N. 2009. Immune Responses and Protection Against Experimental Challenge after Vaccination of Bison with Brucella abortus Strains RB51 or RB51 Overexpressing Superoxide Dismutase and Glycosyltransferase Genes. Clinical and Vaccine Immunology. 16(4):535-540.
Pathogenesis and epidemiology of Brucellosis in Yellowstone bison: serologic and culture results from adult females and their offspring - (Peer Reviewed Journal)
Rhyan, J.C., Aune, K., Roffe, T., Ewalt, D., Hennager, S., Gidlewski, T., Olsen, S.C., Clarke, R., Jones, L., Sweeney, S. 2009. Pathogenesis and Epidemiology of Brucellosis in Yellowstone Bison: Serologic and Culture Results from Adult Females and their Progeny. Journal of Wildlife Diseases. 45(3):729-739.
Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus) - (Peer Reviewed Journal)
Waters, W.R., Nonnecke, B.J., Gibbs, S.E., Yabsley, M.J., Schmitt, S.M., Cosgrove, M.K., Palmer, M.V., Thacker, T.C., Olsen, S.C., Horst, R.L., Reinhardt, T.A. 2009. Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus). International Journal for Vitamin and Nutrition Research. 79(3):180-187.
Experimental Infection of Richardson's Ground Squirrels (Spermophilus richardsonii) with Attenuated and Virulent Strains of Brucella abortus - (Peer Reviewed Journal)
Nol, P., Olsen, S.C., Rhyan, J.C. 2009. Experimental Infection of Richardson's Ground Squirrels (Spermophilus richardsonii) with Attenuated and Virulent Strains of Brucella abortus. Journal of Wildlife Diseases. 45(1):189-195.
Defensin Susceptibility and Colonization in the Mouse Model of AJ100, a Polymyxin B Resistant, Brucella abortus RB51 Isolate - (Peer Reviewed Journal)
Halling, S.M., Jensen, A.E., Olsen, S.C. 2008. Defensin Susceptibility and Colonization in the Mouse Model of AJ100, a Polymyxin B Resistant, Brucella abortus RB51 Isolate. Current Microbiology. 56(2008):274-278.
An Aerosolized Brucella spp. Challenge Model for Laboratory Animals - (Peer Reviewed Journal)
Olsen, S.C., Waters, W.R., Stoffregen, W.C. 2007. An Aerosolized Brucella spp. Challenge Model for Laboratory Animals. Zoonoses and Public Health. 54(8):281-285.
Vaccination in Conservation Medicine - (Proceedings)
Plumb, G., Babiuk, L., Mazet, J., Olsen, S.C., Pastoret, P.P., Rupprecht, C., Slate, D. 2007. Vaccination in Conservation Medicine. Electronic Publication. Available: www.nfid.org/pdf/conferences/vaccine06abstracts.pdf
Diagnostic Characterization of a Feral Swine Herd Enzootically Infected with Brucella - (Peer Reviewed Journal)
Stoffregen, W.C., Olsen, S.C., Wheeler, C.J., Bricker, B.J., Palmer, M.V., Jensen, A.E., Halling, S.M., Alt, D.P. 2007. Diagnostic Characterization of a Feral Swine Herd Enzootically Infected with Brucella. Journal of Veterinary Diagnostic Investigation. 19(3):227-237.
Blood Culture and Stimulation Conditions for the Diagnosis of Tuberculosis in Cervids by the Cervigam Assay - (Peer Reviewed Journal)
Waters, W.R., Palmer, M.V., Thacker, T.C., Orloski, K., Nol, P., Harrington, N.P., Olsen, S.C., Nonnecke, B.J. 2008. Blood Culture and Stimulation Conditions for the Diagnosis of Tuberculosis in Cervids by the Cervigam Assay. Veterinary Record. 162(7):203-208.
Control Measures for Brucellosis in the United States - (Proceedings)
Olsen, S.C. 2006. Control Measures for Brucellosis in the United States. In: Proceedings of the Korean Society of Veterinary Science, September 27-28, 2006, Tonyoung City, Korea. p. 43-44.
EFFECTS OF PRE-CULTURE HOLDING TIME AND TEMPERATURE ON INTERFERON-GAMMA RESPONSES IN WHOLE BLOOD CULTURES FROM MYCOBACTERIUM BOVIS-INFECTED CATTLE - (Peer Reviewed Journal)
Waters, W.R., Nonnecke, B.J., Olsen, S.C., Palmer, M.V. 2007. Effects of pre-culture holding time and temperature on interferon-gamma responses in whole blood cultures from Mycobacterium bovis-infected cattle. Veterinary Microbiology. 119(2-4):277-282.
IMMUNE RESPONSES OF ELK TO INITITAL AND BOOSTER VACCINATIONS WITH BRUCELLA ABORTUS STRAIN RB51 OR 19 - (Peer Reviewed Journal)
Olsen, S.C., Fach, S.J., Palmer, M.V., Sacco, R.E., Stoffregen, W.C., Waters, W.R. 2006. Immune Responses of Elk to Initital and Booster Vaccinations with Brucella abortus Strain RB51 or 19. Clinical and Vaccine Immunology. 13(10):1098-1103.
RESULTS OF VACCINE TRIALS USING BRUCELLA ABORTUS RB51 IN DOMESTIC SWINE - (Proceedings)
Stoffregen, W.C., Olsen, S.C., Bricker, B.J. 2006. Results of Vaccine Trials using Brucella Abortus RB51 in Domestic Swine. In: Proceedings of the International pig Veterinary Society, July 14-20, Copenhagen, Denmark. p. 89.
Parenteral Vaccination of Domestic Pigs with Brucella abortus strain RB51 - (Peer Reviewed Journal)
Stoffregen, W.C., Olsen, S.C., Bricker, B.J. 2006. Parenteral Vaccination of Domestic Pigs with Brucella abortus strain RB51. American Journal of Veterinary Research. 67(10):1802-1808.
EFFICACY OF STRAIN RB51 VACCINE IN HEIFERS AGAINST EXPERIMENTAL BRUCELLOSIS - (Peer Reviewed Journal)
Poester, F.P., Goncalves, V.S., Paixao, T.A., Santos, R.L., Olsen, S.C., Schurig, G., Lage, A.P. 2006. Efficacy of strain RB51 vaccine in heifers against experimental brucellosis. Vaccine. 24(2006):5327-5334.
BRUCELLA ABORTUS STRAIN RB51: APPLICATIONS AND EFFECTIVENESS IN DOMESTIC LIVESTOCK AND OTHER SPECIES OF INTEREST - (Proceedings)
Olsen, S.C. 2006. Brucella abortus strain RB51: Applications and Effectiveness in Domestic Livestock and other Species of Interest. Proceedings of Conference on Brucellosis in Korea, April 19-23, 2006, Seoul, Korea. p. 171-175.
IDENTIFICATION OF A HAEMOMYCOPLASMA SPECIES IN ANEMIC REINDEER (RANGIFER TARANDUS) - (Peer Reviewed Journal)
Stoffregen, W.C., Alt, D.P., Palmer, M.V., Olsen, S.C., Waters, W.R., Stasko, J.A., Peterson Burch, B.D. 2006. Identification of a Haemomycoplasma Species in Anemic Reindeer (Rangifer Tarandus). Journal of Wildlife Diseases. 42(2):249-258.
HOST SPECIES DIFFERENCES IN RESPONSES TO BRUCELLA OR MYCOBACTERIUM VACCINES - (Abstract Only)
Olsen, S.C., Stoffregen, W.C. 2005. Host species differences in responses to brucella or mycobacterium vaccines [abstract]. Research Workers in Animal Diseases Conference Proceedings. p. 99.
THE ESSENTIAL ROLE OF VACCINES IN BRUCELLOSIS CONTROL AND ERADICATION PROGRAMS FOR LIVESTOCK - (Peer Reviewed Journal)
Olsen, S.C., Stoffregen, W.C. 2005. The essential role of vaccines in brucellosis control and eradication programs for livestock. Expert Review of Vaccines. 4(6):915-928.
Report of the Vaccine Working Group. Enhancing Brucellosis Vaccines, Vaccine Delivery, and Surveillance Diagnostics for Elk and Bison in the Greater Yellowstone Area - (Proceedings)
Olsen, S.C., Mamer, P. 2005. Report of the Vaccine Working Group. Enhancing Brucellosis Vaccines, Vaccine Delivery, and Surveillance Diagnostics for Elk and Bison in the Greater Yellowstone Area. Proceedings of the United States Animal Health Association Working Symposium, August 16-18, 2005, Laramie, Wyoming, p. 5-12.
IMMUNOLOGIC RESPONSES OF BISON TO VACCINATION WITH BRUCELLA ABORTUS STRAIN RB51: COMPARISON OF PARENTERAL TO BALLISTIC DELIVERY VIA COMPRESSED PELLETS OR PHOTOPOLYMERIZED HYDROGELS - (Peer Reviewed Journal)
Olsen, S.C., Christie, R.J., Grainger, D.W., Stoffregen, W.C. 2005. Immunologic responses of bison to vaccination with Brucella abortus strain RB51: Comparison of parenteral to ballistic delivery via compressed pellets or photopolymerized hydrogels. Vaccine. 24(2006):1346-1353.
STATUS OF THE RB51 GENOME SEQUENCING PROJECT - (Abstract Only)
Bricker, B.J., Peterson Burch, B.D., Alt, D.P., Halling, S.M., Stoffregen, W.C., Olsen, S.C. 2005. Status of the RB51 Genome Sequencing Project [abstract]. 58th Brucellosis Research Conference. p. 92.
PHOTOPOLYMERIZED HYDROGEL CARRIERS FOR LIVE VACCINE BALLISTIC DELIVERY - (Peer Reviewed Journal)
Christie, R.J., Findley, D.J., Dunfee, M., Hansen, R., Olsen, S.C., Grainger, D.W. 2006. Photopolymerized hydrogel carriers for live vaccine ballistic delivery. Vaccine. 24(9):1462-9.
LYMPHOCYTES FROM ONE SIDE OF THE BOVINE MAMMARY GLAND MIGRATE TO THE CONTRA LATERAL GLAND AND LYMPH NODE TISSUE - (Peer Reviewed Journal)
Kimura, K., Harp, J.A., Goff, J.P., Olsen, S.C. 2005. Lymphocytes from one side of the bovine mammary gland migrate to the contra lateral gland and lymph node tissue. Veterinary Immunology and Immunopathology. 108(3-4):409-415.
COMPLETION OF THE GENOME SEQUENCE OF BRUCELLA ABORTUS AND COMPARISON TO THE HIGHLY SIMILAR GENOMES OF B. MELITENSIS AND B. SUIS - (Peer Reviewed Journal)
Halling, S.M., Peterson Burch, B.D., Bricker, B.J., Zuerner, R.L., Qing, Z., Li, L., Kapur, V., Alt, D.P., Olsen, S.C. 2005. Completion of the genome sequence of brucella abortus and comparison to the highly similar genomes of b. melitensis and b. suis. Journal of Bacteriology. 187(8):2715-26.
IMMUNOLOGIC RESPONSES OF BISON TO VACCINATION WITH FRESH OR LYOPHILIZED BRUCELLA ABORTUS STRAIN RB51 - (Abstract Only)
Olsen, S.C., Rhyan, J., Stoffregen, W.C., Gidlewski, T. 2004. Immunologic responses of bison to vaccination with fresh or lyophilized brucella abortus strain rb51 [abstract]. Research Workers in Animal Diseases Conference Proceedings. p.98.
INFLUENCE OF THE SPIROVAC(R) LEPTOSPIROSIS VACCINE ON IMMUNOLOGIC RESPONSES OF BISON TO BRUCELLA ABORTUS STRAIN RB51 VACCINE - (Abstract Only)
Olsen, S.C., Stoffregen, W.C., Zuerner, R.L., Alt, D.P. 2004. Influence of the spirovac(r) leptospirosis vaccine on immunologic responses of bison to brucella abortus strain rb51 vaccine [abstract]. Research Workers in Animal Diseases Conference Proceedings. p.98.
NADC STUDIES ON BISON BRUCELLOSIS VACCINES AND MOLECULAR TECHNIQUES FOR BRUCELLA EPIDEMIOLOGIC TRACEBACKS - (Proceedings)
Bricker, B.J., Olsen, S.C. 2004. NADC studies on bison brucellosis vaccines and molecular techniques for brucella epidemiologic tracebacks. United States Animal Health Association Proceedings. p. 201-204.
CAN LYMPHOCYTES FROM ONE SIDE OF BOVINE MAMMARY GLAND MIGRATE TO THE CONTRALATERAL GLAND AND LYMPH NODE TISSUE? - (Abstract Only)
Kimura, K., Harp, J.A., Oesper, J.C., Goff, J.P., Olsen, S.C. 2004. Can lymphocytes from one side of bovine mammary gland migrate to the contralateral gland and lymph node tissue [abstract]. Great Lakes International Imaging and Flow Cytometry Association. p. 17.
IDENTIFICATION OF HAEMOMYCOPLASMA SPECIES IN ANEMIC REINDEER (RANGIFER TARANDUS) - (Abstract Only)
Stoffregen, W.C., Alt, D.P., Palmer, M.V., Olsen, S.C., Waters, W.R. 2004. Identification of haemomycoplasma species in anemic reindeer (rangifer tarandus) [abstract]. American College of Veterinary Pathologists Meeting. 41:550.
RESULTS OF A VACCINE TRIAL USING BRUCELLA ABORTUS RB51 IN A FERAL SWINE HERD ENZOOTICALLY INFECTED WITH BRUCELLA IN THE UNITED STATES OF AMERICA - (Proceedings)
Stoffregen, W.C., Bricker, B.J., Jensen, A.E., Wheeler, C.J., Olsen, S.C. 2004. Results of a vaccine trial using brucella abortus rb51 in a feral swine herd enzootically infected with brucella in the United States of America. Pig Veterinary Society International Congress Proceedings. Paper No. 717.
SAFETY OF BRUCELLA ABORTUS STRAIN RB51 IN BLACK BEARS - (Peer Reviewed Journal)
Olsen, S.C., Rhyan, J., Gidlewski, T., Goff, J.P., Stoffregen, W.C. 2004. Safety of Brucella abortus strain RB51 in Black Bears. Journal of Wildlife Diseases.40(3):429-33.
COMPARISON OF IMMUNOLOGIC RESPONSES OF BISON (BISON BISON) AND CATTLE TO VACCINATIONS WITH BRUCELLA ABORTUS STRAIN RB51 - (Proceedings)
Olsen, S.C., Stoffregen, W.C., Waters, W.R. 2003. Comparison of immunologic responses of bison (bison bison) and cattle to vaccinations with brucella abortus strain rb51 [abstract]. Proceedings of the 84th Annual Meeting of the Conference of Research Workers in Animal Diseases. Poster No. 67.
CHARATERIZATION OF BRUCELLA ISOLATES OF FERAL SWINE FROM COASTAL SOUTH CAROLINA - (Abstract Only)
THE USE OF FTA CARDS IN MOLECULAR DIAGNOSIS TECHNIQUES FOR BRUCELLOSIS - (Abstract Only)
IMMUNOLOGIC RESPONSES AND EFFICACY OF HAND OR BALLISTIC VACCINATION OF BISON (BISON BISON) WITH BRUCELLA ABORTUS STRAIN RB51 - (Abstract Only)
Olsen, S.C., Stoffregen, W.C., Waters, W.R. 2003. Immunologic responses and efficacy of hand or ballistic vaccination of bison (bison bison) with brucella abortus strain rb51(abstact). Wildlife Disease Association. Paper No. 108.
FERAL SWINE BRUCELLOSIS IN THE UNITED STATES OF AMERICA - (Abstract Only)
SAFETY OF REVACCINATION OF PREGNANT BISON WITH BRUCELLA ABORTUS STRAIN RB51 DURING PREGNANCY - (Peer Reviewed Journal)
Olsen, S.C., Holland, S. 2003. Safety of revaccination of pregnant bison with brucella abortus strain rb51 during pregnancy. Journal of Wildlife Diseases. 39:824-829.
PORCINE BRUCELLOSIS ()
Olsen, S.C. 2004. Porcine brucellosis. In: OIE Terrestrial Manual 2004. 5th Edition. Paris, France:Office international des epizooties. p. 777-784.
BRUCELLA ()
Olsen, S.C., Thoen, C.O., Cheville, N.F. 2004. Brucella. In: Gyles,C.E., Prescott, J.F., Songer, J.G., Thoen, C.O., editors.Pathogenesis of Bacterial Infections in Animals. Ames,IA:Blackwell Publishing. p. 309-320.
IMMUNE RESPONSES OF ELK TO MYCOBACTERIUM BOVIS BACILLUS CALMETTE GUERIN VACCINATION - (Peer Reviewed Journal)
Waters, W.R., Palmer, M.V., Olsen, S.C., Sacco, R.E., Whipple, D.L. 2003. Immune responses of elk to mycobacterium bovis bacillus calmette guerin vaccination. Vaccine. Vol. 21(13-14), p. 1518-1526.
ANALYSIS OF MITOGEN-STIMULATED LYMPHOCYTE SUBSET PROLIFERATION AND NITRIC OXIDE PRODUCTION BY PERIPHERAL BLOOD MONONUCLEAR CELLS OF CAPTIVE ELK (CERVUS ELAPHUS) - (Peer Reviewed Journal)
GRANULOMATOUS ORCHITIS ASSOCIATED WITH HISTOPLASMA-LIKE ORGANISMS IN PORCUPINES (ERETHIZON DORSATUM) - (Peer Reviewed Journal)
LYMPHOCYTE SUBSET PROLIFERATIVE RESPONSES OF MYCOBACTERIUM BOVIS-INFECTED CATTLE: GAMMA/DELTA TCR+ AND CD4+ T CELLS ARE THE PREDOMINANT CELLS RESPONDING - (Peer Reviewed Journal)
SURVIVAL OF BRUCELLA ABORTUS STRAIN RB51 LYOPHILIZED AND LIQUID VACCINE UNDER DIFFERENT STORAGE CONDITIONS - (Peer Reviewed Journal)
LYMPHOCYTE SUBSET PROLIFERATIVE RESPONSES OF MYCOBACTERIUM BOVIS-INFECTED CATTLE - (Abstract Only)
MHC CLASS II-RESTRICTED, CD4+ T CELL PROLIFERATIVE RESPONSES OF PERIPHERAL BLOOD MONONUCLEAR CELLS FROM MYCOBACTERIUM BOVIS-INFECTED WHITE-TAILED DEER - (Peer Reviewed Journal)
RESPONSES OF ADULT CATTLE TO VACCINATION WITH A REDUCED DOSE OF BRUCELLA ABORTUS STRAIN RB51 - (Peer Reviewed Journal)
IMMUNE RESPONSES AND EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 VACCINE IN BISON (BISON BISON) - (Abstract Only)
AVAILABLE VACCINES FOR THE CONTROL OF BRUCELLOSIS IN ANIMALS - (Proceedings)
RESEARCH NEEDS ON VACCINE DEVELOPMENT AND VACCINATION SCHEMES FOR BRUCELLOSIS CONTROL/ERADICATION PROGRAMS - (Proceedings)
BIOSAFETY OF BRUCELLA ABORTUS STRAIN RB51 IN ADULT BISON BULLS AND EFFICACYAS A CALFHOOD VACCINE IN BISON - (Proceedings)
ANTIGEN-SPECIFIC PROLIFERATION OF PERIPHERAL BLOOD LYMPHOCYTE SUBSETS FROM MYCOBACTERIUM BOVIS-INFECTED WHITE TAILED DEER - (Abstract Only)
DEER TO DEER TRANSMISSION OF MYCOBACTERIUM BOVIS - (Abstract Only)
MYCOBACTERIUM BOVIS INFECTION IN WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) - (Abstract Only)
BIOSAFETY OF PARENTERAL BRUCELLA ABORTUS STRAIN RB51 VACCINE IN BISON CALVES - (Peer Reviewed Journal)
BIOSAFETY AND ANTIBODY RESPONSES FOLLOWING VACCINATION OF ADULT BISON BULLSWITH BRUCELLA ABORTUS STRAIN RB51 - (Peer Reviewed Journal)
EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 AS A CALFHOOD VACCINATION FORO BISON - (Abstract Only)
CLONING, SEQUENCING, AND EXPRESSION OF BOVINE INTERLEUKIN-18 - (Abstract Only)
BIOSAFETY, SEROLOGY, AND EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 IN CATTLE - (Proceedings)
BIOSAFETY, SEROLOGY, AND EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 IN CATTLE INTL CONG ANTHRAX, BRUC, CBPP, MYCO DIS, AND CLOSTRIDIAL DIS SOUTH AFRICA - (Abstract Only)
PATHOLOGIC, BACTERIOLOGIC, AND IMMUNOLOGIC FINDINGS IN WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) EXPERIMENTALLY INFECTED WITH MYCOBACTERIUM BOVIS - (Abstract Only)
TUBERCULOSIS IN WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) - (Proceedings)
TUBERCULOSIS IN WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) INTL CONGRESS ANTHRAX, BRUC, CBPP, MYCOBACT DIS, & CLOSTERIDIAL DIS. KREEGER NATIONAL PARK, SOUTH AFRICA; AUGUST 9-15, 1998 - (Abstract Only)
EXPERIMENTAL INFECTION OF WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) WITH MYCOBACTERIUM BOVIS, THE CAUSATIVE AGENT OF TUBERCULOSIS. - (Proceedings)
SEROLOGIC RESPONSES, TISSUE LOCALIZATION, CLEARANCE, AND HISTOLOGY OF BRUCELLA ABORTUS STRAIN RB51 IN BISON CALVES UNDER FIELD CONDITIONS - (Abstract Only)
BIOSAFETY OF BRUCELLA ABORTUS STRAIN RB51 IN ADULT BISON BULLS - (Abstract Only)
ISOLATION OF BRUCELLA ABORTUS STRAIN RB51 FROM VACCINATED BISON (BISON BISON) - (Abstract Only)
EXPERIMENTAL USE OF A DOT-BLOT ASSAY TO MEASURE SEROLOGIC RESPONSES OF CATTLE VACCINATED WITH BRUCELLA ABORTUS STRAIN RB51 - (Peer Reviewed Journal)
SEROLOGIC RESPONSES, BIOSAFETY AND CLEARANCE OF BRUCELLA ABORTUS STRAIN RB51 IN 7 MONTH OLD BISON - (Abstract Only)
BRUCELLA ABORTUS STRAIN RB51: A NEW BRUCELLOSIS VACCINE FOR CATTLE - (Peer Reviewed Journal)
SAFETY AND IMMUNOGENICITY OF BRUCELLA ABORTUS STRAIN RB51 VACCINATION IN PREGNANT CATTLE - (Peer Reviewed Journal)
SAFETY AND IMMUNOGENICITY OF THE VACCINE BRUCELLA ABORTUS STRAIN RB51 IN PREGNANT CATTLE - (Abstract Only)
SEROLOGIC RESPONSES, BIOSAFETY AND CLEARANCE OF BRUCELLA ABORTUS STRAIN RB51 IN 7 MONTH OLD BISON - (Abstract Only)
USE OF A DOT-BLOT ASSAY TO MONITOR SEROLOGIC RESPONSES IN BRUCELLA ABORTUS STRAIN RB51-VACCINATED CATTLE - (Abstract Only)
IMMUNE RESPONSES AND RESISTANCE TO BRUCELLOSIS IN MICE VACCINATED ORALLY WITH BRUCELLA ABORTUS STRAIN RB51 - (Abstract Only)
SAFETY AND IMMUNOGENICITY OF BRUCELLA ABORTUS STRAIN RB51 VACCINATION IN PREGNANT CATTLE - (Abstract Only)
BRUCELLA ABORTUS STRAIN RB51 AS A CALFHOOD VACCINE IN BISON OR ADULT VACCINE IN PREGNANT CATTLE - (Proceedings)
BRUCELLOSIS IN BISON: AN UPDATE ()
IMMUNE RESPONSES AND RESISTANCE TO BRUCELLOSIS IN MICE VACCINATED ORALLY WITH BRUCELLA ABORTUS RB51 - (Peer Reviewed Journal)
ABORTION AND PLACENTITIS IN PREGNANT BISON (BISON BISON) INDUCED BY THE VACCINE CANDIDATE BRUCELLA ABORTUS STRAIN RB51 - (Peer Reviewed Journal)
SEROLOGIC RESPONSES OF BRUCELLA ABORTUS STRAIN 19 CALFHOOD-VACCINATED CATTLE FOLLOWING ADULT VACCINATION WITH STRAIN RB51 - (Peer Reviewed Journal)
UPDATE ON A NEW BRUCELLOSIS VACCINE ()
EFFECTS OF AGE AT VACCINATION ON EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 TO PROTECT CATTLE AGAINST BRUCELLOSIS - (Peer Reviewed Journal)
ANTIBODY RESPONSES TO BRUCELLA ABORTUS 2308 IN CATTLE VACCINATED WITH B. ABORTUS RB51 ()
LYMPHOCYTE PROLIFERATION IN RESPONSE TO BRUCELLA ABORTUS RB51 AND 2308 PROTEINS IN RB51-VACCINATED OR 2308-INFECTED CATTLE - (Peer Reviewed Journal)
ANTIBODY RESPONSES TO BRUCELLA ABORTUS 2308 IN CATTLE VACCINATED WITH B. ABORTUS RB51 - (Abstract Only)
ISOLATION OF ANTIGENIC OUTER MEMBRANE PROTEINS FROM BRUCELLA ABORTUS RB51 BY LECTIN AFFINITY CHROMATOGRAPHY - (Abstract Only)
EFFECTS OF BRUCELLA ABORTUS 2308 AND RB51 PROTEINS ON BOVINE T CELL PROLIFERATION IN RESPONSE TO SPECIFIC ANTIGEN INTERLEUKIN 1, OR INTERLEUKIN 2. - (Abstract Only)
COMPARATIVE EFFECTS OF BOVINE CYTOKINES ON CATTLE AND BISON PERIPHERAL BLOOD MONONUCLEAR CELL PROLIFERATION - (Abstract Only)
LYMPHOCYTE PROLIFERATION IN RESPONSE TO BRUCELLA ABORTUS RB51 AND 2308 PROTEINS IN RB51-VACCINATED OR 2308-INFECTED CATTLE - (Abstract Only)
SEROLOGIC RESPONSES OF BRUCELLA ABORTUS STRAIN 19 CALFHOOD-VACCINATED CATTLE FOLLOWING ADULT VACCINATION WITH STRAIN RB51 - (Abstract Only)
LYMPHOCYTE PROLIFERATIVE RESPONSES OF GOATS VACCINATED WITH B. MELITENSIS STRAINS 16M AND 201 - (Abstract Only)
PLACENTITIS INDUCED BY BRUCELLA ABORTUS STRAIN RB51 - (Proceedings)
EFFICACY OF BRUCELLA ABORTUS STRAIN RB51 TO PROTECT CATTLE AGAINST BRUCELLOSIS - (Proceedings)
COMPARISON OF SPLEEN CELL PROLIFERATION IN RESPONSE TO BRUCELLA ABORTUS STRAIN 2308 LIPOPOLYSACCARIDE OR PROTEINS IN MICE VACCINATED WITH STRAIN 19OR RB51 - (Peer Reviewed Journal)
BACTERIAL PERSISTENCE AND IMMUNITY IN GOATS VACCINATED WITH A PURE DELETION MUTANT OR THE PARENTAL 16 M STRAIN OF BRUCELLA MELITENSIS - (Peer Reviewed Journal)
ARS News Articles