Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 1/1/2002
Publication Date: 2/23/2002
Citation: Behall, K.M., Scholfield, D.J., Hallfrisch, J.G., Liljeberg-Elmstah, H.G. 2002. Comparison of glucose and hormone responses to different levels of amylose and b-glucan. first annual nutrition week; san diego, ca; february 23-27, 2002. Meeting Abstract.
Technical Abstract: Previous studies conducted at the Beltsville Human Nutrition Research Center have found improved glucose and insulin responses after consumption of soluble oat fiber or high amylose cornstarch. This study sought to determine if high amylose starch and soluble fiber improve glycemic parameters independently. Twenty women (10 with a BMI< 25 and 10 with a BMI>28), aged 35-55 were fed a controlled equilibration diet for 3 days in conjunction with each test. On day three, fasting subjects consumed a test meal (1 gm carbohydrate/kg body weight) as glucose or one of 9 muffins containing 30, 50, or 70% amylose cornstarch and approximately 0.5, 1.2 or 5 g of B-glucan/100 g carbohydrate. The 10 test meals were fed in a Latin Square design. Data were analyzed by using a mixed procedure ANOVA. Blood samples were collected at fasting, 1/2 , 1, 2, 3, and 4 hr after the test meal and 1/2, 1, and 2 hr after a standardized lunch. Glucose and insulin responses were significantly different by treatment. Both high B-glucan and high amylose reduced glucose response significantly post-tolerance test and post second meal. The highest B- glucan level was the most effective in lowering insulin response. The greatest reduction in area under the curve occurred after the tolerances containing high B-glucan and mixed or high amylose starch, and after the second meals following all high B-glucan tolerances regardless of starch. Thyroid stimulating hormone (TSH) showed a significant treatment by group interaction. Overweight subjects had lower TSH levels than controls with varied responses to the different treatments. Leptin levels of controls averaged half those of overweight subjects. Insulin resistance (I30/I0) showed a significant difference between treatments.