U.S. Dietary Supplement Ingredient Database (DSID): Adult Multivitamin/Mineral (MVM) Study Results and Implementation Strategies for the First Data Release

Authors: Roseland, Janet; ANDREWS, KAREN - JOHNS HOPKINS UNIV; ZHAO, CUIWEI - JOHNS HOPKINS UNIV; Holden, Joanne; SCHWEITZER, AMY - JOHNS HOPKINS UNIV; DOUGLASS, LARRY - UN OF MD; Harnly, James - Jim; Wolf, Wayne; DWYER, JOHANNA - ODS-NIH; PICCIANO, MARY FRANCES - ODS-NIH; SALDANHA, LEILA - ODS-NIH; YETLEY, ELIZABETH - ODS-NIH; FISHER, KENNETH - ODS-NIH

Submitted to: National Nutrient Databank Conference
Publication Type: Abstract Only
Publication Acceptance Date: 2/7/2008
Publication Date: 5/12/2008
Citation: Roseland, J.M., Andrews, K., Zhao, C., Holden, J.M., Schweitzer, A., Douglass, L., Harnly, J.M., Wolf, W.R., Dwyer, J., Picciano, M., Saldanha, L., Yetley, E., Fisher, K. 2008. U.S. Dietary Supplement Ingredient Database (DSID): Adult Multivitamin/Mineral (MVM) study results and implementation strategies for the first data release. 32nd National Nutrient Databank Conference, May 12-14, 2008, Ottawa, Ontario, Canada.

Interpretive Summary:

Technical Abstract: Objectives: The objectives of this study were to provide nationally representative estimates for 19 nutrients in representative adult MVM products based upon chemical analysis, and to assess variability in specific products. Methods and Materials: USDA's NDL obtained data from market research and national surveys to develop a statistical sampling plan for purchasing representative DS products in specific market channels in 6 geographic regions. Nutrient levels for these products were analyzed using validated laboratory methods. Statistical analysis using regression techniques identified nutrient-based patterns of variance per nutrient. Final results will be compiled using an integrated relational database system. The data release format will include estimates of individual nutrient values with indicators of variability, nutrient estimates for default and generic products, and documentation of data sources. Analytical Results: Results from the analysis of 6 representative lots of 35 high market share products indicated that for 12 nutrients (calcium, copper, iron, magnesium, manganese, niacin, phosphorus, potassium, riboflavin, vitamin C, alpha-tocopherol, and zinc), the mean % differences from label were <12% with standard deviations <12%. For 3 nutrients, selenium, vitamin B6, and chromium, the mean values were significantly above labeled levels. Results for the remaining 4 nutrients were more variable than the results of the other 15 nutrients. Significance: The Nutrient Data Laboratory, ARS, USDA, is collaborating with the Office of Dietary Supplements to develop the DSID. It is important to monitor actual composition of DS products because of their prevalent use, since >50% of American adults report use of a DS within the past thirty days. DSID will support surveys estimating the intake of nutrients contributed by dietary supplement products. Analytically-based estimates from DSID can be combined with records of DS intake to estimate nutrient intake, assisting researchers in making more accurate quantitative estimates of total intake and evaluating the nutritional status of Americans. Funding Disclosure: This research was funded by USDA and the Office of Dietary Supplements at the National Institutes of Health, Interagency agreement ODS/NIH Y4-HV-0051.