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ARS Home » Research » Publications at this Location » Publication #211555

Title: IDENTIFICATION OF KNOWN PHAGE ENDOLYSIN GENES BY PCR

Author
item ABAEV, I
item KOROBOVA, O
item PECHERSKIKH, E
item DMITREKNO, O
item Donovan, David

Submitted to: Interscience Conference on Antimicrobial Agents & Chemotherapy Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: 8/5/2008
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: S. aureus phage endolysins degrade staphylococcal peptidoglycan when released from within an infected cell. Some have been shown to also be effective when purified and exposed to the bacteria externally (lysis 'from without'). These have been proposed for use in antimicrobial applications, especially against MRSA strains.