Submitted to: Meeting Abstract
Publication Type: Proceedings
Publication Acceptance Date: 7/15/1999
Publication Date: N/A
Technical Abstract: Phytonutrient research was until recently the province of natural product chemists and consisted of primarily anecdotal clinical references. In recent years an extensive set of qualitative and semi-quantitative nutritional epidemiological data has been developed. This developing base of epidemiological data is now being supplemented by biochemical, mechanistic and genetic nutritional epidemiology of a more quantitative nature. As we seek to understand the mechanisms which explain a large body of epidemiological evidence, newer laboratory methods have been developed and are under development, and are discussed herein. Though there is a continuing need for even more discriminative nutritional epidemiology to drive the basic research in this area forward, the focus of in-vitro, animal and clinical (human) studies must continue to be refined and appropriate biomarkers for chronic and acute (death) disease endpoints must be developed.