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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Diet, Genomics and Immunology Laboratory » People & Locations » Jae Park

Jae B Park
Diet, Genomics and Immunology Laboratory
Research Chemist

Phone: (301) 504-8365 ext. 240
Fax: (301) 504-9062
Room 133

10300 BALTIMORE AVE
BLDG 307 BARC-EAST
BELTSVILLE , MD 207052350
Projects
Health Promoting Roles of Food Bio-Active Phenolic Compounds on Obesity-Altered Metabolic Functions and Physiology
In-House Appropriated (D)
  Accession Number: 426502
Investigation on Phytochemical and Macronutrient Properties of Soybeans Grown in Romania
Non-Funded Cooperative Agreement (N)
  Accession Number: 429701
Health Promoting Roles of Food Bio-Active Phenolic Compounds on Obesity-Altered Hearth, and Kidney Functions
Non-Assistance Cooperative Agreement (S)
  Accession Number: 431723
Health Promoting Roles of Food bio-Active Phenolic Compounds on Obesity-Altered Metabolic Functions and Physiology
Non-Assistance Cooperative Agreement (S)
  Accession Number: 433533
Metabolic Effects of Prenatal Exposure to Particulate Matter
Non-Assistance Cooperative Agreement (S)
  Accession Number: 428958

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
In silico screening and in vitro activity measurement of javamide analogues as potential p38 MAP kinase inhibitors. -
Park, J.B. 2017. In silico screening and in vitro activity measurement of javamide analogues as potential p38 MAP kinase inhibitors.. International Journal of Molecular Sciences. 18(12)pii:E2704. https://doi.org/10.3390/ijms ijms18122704.
Reactive oxidative species formation and unregulated particulate emissions from blended diesel and biodiesel light-duty engine emissions -
Park, J.B. 2017. Reactive oxidative species formation and unregulated particulate emissions from blended diesel and biodiesel light-duty engine emissions. Journal of Environmental Science and Technology. doi: 10.1021/acs.energyfuels.7b00698.
Methyl (E)-(3,4-dihydroxyphenyl)acryloyl)tryptophanate can suppress MCP-1 expression by inhibiting p38 MAP kinase and NF-kB in LPS-stimulated differentiated THP-1 cells -
Park, J.B., Wang, T.T. 2017. Methyl(E)-(3,4-dihydroxyphenyl)acryloyl) tryptophanate can suppress MCP-1 expression by inhibiting p38 MAP kinase and NF-kB in LPS-stimulated differentiated THP-1 cells. European Journal of Pharmacology. 8(10):149-155. doi: 10.1016/j.ejphar.2017.07.006.
N-caffeoyltryptomine, a potent anti-inflammatory phenolic amide, suppressed MCP-1 expression in LPS-stimulated THP-1 cells and rats fed with a high fat diet -
Park, J.B. 2017. N-caffeoyltryptomine, a potent anti-inflammatory phenolic amide, suppressed MCP-1 expression in LPS-stimulated THP-1 cells and rats fed with a high fat diet. International Journal of Molecular Sciences. 18(6). pii:E1148. doi: 10.3390/ijms18061148.
Javamide-I-O-methyl ester increases p53 acetylation and induces cell death via activating caspase 3/7 in monocytic THP-1 cells -
Park, J.B. 2016. Javamide-I-O-methyl ester increases p53 acetylation and induces cell death via activating caspase 3/7 in monocytic THP-1 cells. Phytomedicine. 23(13):1647-1652. doi: 10.1016/j.phymed.2016.10.004.
Activity-guided isolation of a sirtuin2 inhibiting compound from coffee: structural and activity confirmation of Javamide-II (N-caffeoyltryptophan)and its cellular effects on histone H3 and alpha-tubulin -
Park, J.B. 2016. Activity-guided isolation of a sirtuin2 inhibiting compound from coffee: structural and activity confirmation of Javamide-II (N-caffeoyltryptophan)and its cellular effects on histone H3 and alpha-tubulin. PLoS One. 11(3):e0150392.
Potential biological activities and bioavailability of alfrutamide and caffedymine -
Park, J.B. 2016. Potential biological activities and bioavailability of alfrutamide and caffedymine. Journal of Nutrition. 146(2):437S-4435.
Becatamide Found in Houttuynia cordata suppresses P-selectin expression via inhibiting COX enzyme, not increasing cAMP in platelets -
Park, J.B. 2015. Becatamide found in Houttuynia cordata suppresses P-selectin expression via inhibiting COX enzyme, not increasing cAMP in platelets. Phytotherapy Research. DOI: 10.1002/ptr.5391
Synthesis and characterization of norbelladine, a precursor of Amaryllidaceae alkaloid, as an anti-inflammatory/anti-COX compound -
Park, J.B. 2014. Synthesis and characterization of norbelladine, a precursor of Amaryllidaceae alkaloid, as a potent anti-inflammatory/anti-COX compound. Bioorganic and Medicinal Chemistry Letters. 1:24(23):5381-5384.
Potential effects of chlorogenic acids on platelet activiation Reprint Icon -
Park, J.B. 2014. Potential effects of chlorogenic acids on platelet activiation. In: Preedy, V.R., editor. Coffee in Health and Disease. Academic Press. Amersterdam, Boston, New York. Book Chapter. p709-715.
Synthesis, HPLC measurement and bioavailability of the phenolic amide amkamide -
Park, J.B. 2013. Synthesis, HPLC measurement and bioavailability of the phenolic amide amkamide. Journal of Chromatographic Science. DOI: 10.1093/chromsci/bmt055. Epub 2013 May 27..
Flaxseed lignan and visceral obesity: a closer look at its chemical properties, absorption, metabolism, bioavailability and effects on visceral fat, lipid profile, systemic inflammation and hypertension -
Park, J.B. 2014. Flaxseed lignan and visceral obesity: a closer look at its chemical properties, absorption, metabolism, bioavailability and effects on visceral fat, lipid profile, systemic inflammation and hypertension. In: Watson, R.R., Academic Press. Nutrition in the Prevention and Treatment of Abdominal Obesity. 1st edition. San Diego, CA: Academic Press. p317-328.
Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells -
Park, J.B. 2013. Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells. Food and Function. 4(11):1632-1638Food Funct. doi: 10.1039/c3fo60138b..
Synthesis, biological activity, and bioavailability of moschamine, a safflomide-type phenylpropenoic acid amide found in Centaurea cyanus -
Park, J.B. 2012. Synthesis, biological activity, and bioavailability of moschamine, a safflomide-type phenylpropenoic acid amide found in Centaurea cyanus. Natural Product Research. 26(16):1465-72.
Effects of secoisolariciresinol diglucoside lignan-enriched flaxseed powder on body weight, visceral fat, lipid profile, adipokines, and blood pressure in rats fed a high-fructose and high-fat diet -
Park, J.B., Velasquez, M.T. 2012. Effects of secoisolariciresinol diglucoside lignan-enriched flaxseed powder on body weight, visceral fat, lipid profile, adipokines, and blood pressure in rats fed a high-fructose and high-fat diet. Fitoterapia. 83(5):941-6.
Safflomide increases the expression of adiponectin in vitro and in vivo: Implication for hypoadiponectemia, visceral obesity, and insulin resistance -
Park, J.B., Wang, T.T. 2012. Safflomide increases the expression of adiponectin in vitro and in vivo: Implication for hypoadiponectemia, visceral obesity, and insulin resistance. Journal of Agricultural and Food Chemistry. 25(60):4048-52.
Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells -
Park, J.B. 2011. Protective effects of veskamide, enferamide, becatamide, and oretamide on H2O2-induced apoptosis of PC-12 cells. Phytomedicine. 18(10):843-847.
Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon, thyme, mint, oregano, rosemary, sage, and thyme -
Park, J.B. 2011. Identification and quantification of a major anti-oxidant and anti-inflammatory phenolic compound found in basil, lemon, thyme, mint, oregano, rosemary, sage, and thyme. International Journal of Food Sciences and Nutrition. 62(6):577-584.
Isolation and characterization of N-feruloyltyramine as the P-selectin expression suppressor from garlic (Allium sativum) -
Park, J.B. 2009. Isolation and characterization of N-feruloyltyramine as the P-selectin expression suppressor from garlic (Allium sativum). Journal of Agricultural Food & Chemistry. 57(19):8868-8872.
Serotomide and Safflomide Modulate Forskolin-Stimulated cAMP Formation via 5-HT1 Receptor -
Park, J.B. 2008. Serotomide and safflomide modulate forskolin-stimulated cAMP formation via 5-HT1 receptor. Phytomedicine. http://dx.doi.org/10.1016/j.phymed.2008.04.009.
5-Caffeoylquinic acid and caffeic acid orally administered suppresses P-selectin expression on mouse platelets -
Park, J.B. 2008. 5-Caffeoylquinic acid and caffeic acid orally administered suppresses P-selectin expression on mouse platelets. Journal of Nutritional Biochemistry. 20(10):800-805. Available http://dx.doi.org/10.1016/j.jnutbio.2008.07.009.
Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration -
Park, J.B., Chen, P. 2007. Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration. Journal of Chromatography B: Biomedical Applications. 852(1-2):398-402.
Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-Selectin -
Park, J.B. 2007. Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-selectin. Journal of Agricultural and Food Chemistry.(6):2171-5.
CLOVAMIDE-TYPE PHENYLPROPENOIC ACID AMIDES, N-COUMAROYLDOPAMINE AND N-CAFFEOYLDEPAMINE, INHIBIT PLATELET-LEUKOCYTE INTERACTIONS VIA SUPPRESSING P-SELECTIN EXPRESSION -
Park, J.B., Schoene, N.W. 2006. Clovamide-type phenylpropenoic acid amides, n-coumaroyldopamine and n-caffeoyldepamine, inhibit platelet-leukocyte interactions via suppressing p-selectin expression. Journal of Pharmacology and Experimental Therapeutics. 317(2):813-819.
QUANTITATION OF CLOVAMIDE-TYPE PHENYLPROPENIC ACID AMIDES IN CELLS AND PLASMA USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH A COULOMETRIC ELECTROCHEMICAL DETECTOR -
Park, J.B. 2005. Quantitation of clovamide-type phenylpropenic acid amides in cells and plasma using high performance liquid chromatography with a coulometric electrochemical detector. Journal of Agricultural and Food Chemistry. 53:8135-8140.
QUERCITIN -
Park, J.B. 2005. Quercetin. In: Coates, P., Blackman, M.R., Cragg, G., Levine, M., Moss, J., White, J., editors. Encyclopedia of Dietary Supplements. New York, NY. Marcell Dekker Press. p. 577-585.
N-COUMAROYLDOPAMINE AND ITS ANALOGUES FOUND IN COCOA (THEOBROMA CACAO L.) ARE POTENT BETA-ADRENOCEPTOR AGONISTS SUPPRESSING PLATELET ACTIVITION VIA INCREASING CAMP PRODUCTION. -
Park, J.B. 2005. N-coumaroyldopamine and its analogues found in cocoa (theobroma cacao l.) are potent beta-adrenoceptor agonists suppressing platelet activition via increasing camp production. [Abstract]. Experimental Biology 566(2): 566.
PHENYLPROPENIC ACID AMIDE, N-CAFFEOYLTYRAMINE, INCREASES CAMP VIA BETA 2-ADRENOCEPTORS IN HUMAN MONOCYTIC U937 CELLS; ITS EFFECTS ON MONOCYTE ACTIVATION -
Park, J.B., Schoene, N.W. 2005. Phenylpropenic acid amide, n-caffeoyltyramine, increases camp via beta 2-adrenoceptors in human monocytic u937 cells; its effects on monocyte activation. [Abstract]. Experimental Biology 830(5):830.
N-COUMAROYLDOPAMINE AND N-CAFFEOYLDEPAMINE INCREASE CAMP VIA BETA 2-ADRENOCEPTORS IN MYCLOCYTIC U937 CELLS -
Park, J.B. 2005. N-coumaroyldopamine and n-caffeoyldepamine increase camp via beta 2-adrenoceptors in myelocytic U937 cells. Federation of American Societies for Experimental Biology Journal. 19:497-502.
CLONING, SEQUENCING, AND CHARACTERIZATION OF ALTERNATIVELY SPLICED GLUTAREDOXIN CDNA AND ITS GENOMIC GENE -
Park, J.B., Levin, M. 2005. Cloning, sequencing, and characterization of alternatively spliced glutaredoxin cDNA and its genomic gene. Journal of Biological Chemistry. 280:10427-10434.
A PHENYLPROPENOIC ACID DERIVATIVE, N-CAFFEOLYTYRAMINE, IS A POTENT PHYTOCHEMICAL TO INDUCE APOPTOSIS OF HUMAN TRANSFORMED MYEOLOCYTIC U937 AND HL-60 AND LYMPHOCYTIC JURKAT CELLS -
Park, J.B., Schoene, N.W. 2003. A phenylpropenoic acid derivative, n-caffeolytyramine, is a potent phytochemical to induce apoptosis of human transformed myeolocytic u937 and hl-60 and lymphocytic jurkat cells. Journal of Natural Products.
FLAVONOID INHIBITION OF THE INTESTINAL VITAMIN C TRANSPORTER SVCT1(H) -
N-COUMAROYLTYRAMINE IS A POTENT PHYTOCHEMICAL TO ARREST MEYLOCYTIC U937 AND LYMPHOCYTIC JURKAT CELLS AT THE S PHASE OF CELL CYCLE -
Park, J.B., Schoene, N.W. 2003. N-coumaroyltyramine is a potent phytochemical to arrest meylocytic u937 and lymphocytic jurkat cells at the s phase of cell cycle. Cancer Letters. 202:161-171.
CONCURRENT MEASUREMENTS OF PROMOTER ACTIVITY AND TRANSFECTION EFFICIENCY USING A NEW REPORT VECTOR CONTAINING BOTH PHOTINUS PYRALIS AND RENILLA RENIFORMIS LUCIFERARE GENES -
REDUCTION OF DEHYDROASCORBIC ACID BY HOMOCYSTEINE -
INTRACELLULAR ACCUMULATION OF ASCORBIC ACID IS INHIBITED BY FLAVONOIDS VIA BLOCKING OF DEHYOHROASCORBIC ACID AND ASCORBIC ACID UPTAKES IN HL-60, U937, AND JARKAT CELLS. -
FLAVONOIDS ARE THE POTENTIAL INHIBITORS OF THE GLUCOSE UPTAKE IN U937 -
CRITERIA AND RECOMMENDATIONS FOR VITAMIN C INTAKE -
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