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Title: UTILIZATION OF GENE MAPPING INFORMATION IN LIVESTOCK ANIMALS

Author
item Kappes, Steven - Steve

Submitted to: The International Embryo Technology Society
Publication Type: Proceedings
Publication Acceptance Date: 12/1/1998
Publication Date: N/A
Citation: N/A

Interpretive Summary: A considerable amount of genomic information has been reported in the last few years but it appears that we have barely scratched the surface of the potential genomic information that is available from many different livestock species. We have developed the basic tools to mine some of the information stored in the genome and we have started to see results from using these tools. However, the amount of genomic and proteomics information generated in the next few years will dwarf the information generated in the last few decades. We will need to be creative in the methods we use to accurately measure phenotypes and how the data will be stored and analyzed.

Technical Abstract: A number of recent advances in genomic research will change and improve livestock production in the near future. Genetic linkage maps have been developed for a number of livestock species including cattle, sheep, and pigs. These maps allow scientists to identify chromosomal regions that influence traits of economic importance. This information will lead to improved genetic selection practices by identifying animals with superior copies of the chromosomal regions that affect the selected trait. This mapping information will also be used to identify the genes controlling the trait. A number of genomic regions or loci have already been reported that affect production, carcass or disease traits and in a few cases a specific gene has been identified. Production of transgenic animals with sequence changes in these genes may be beneficial for evaluating the effect of the gene upon the selected trait and more specifically the effect of certain polymorphisms (mutations) within the gene.