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Title: COMPARATIVE MAPPING OF THE CHICKEN GENOME USING THE EAST LANSING REFERENCE POPULATION

Author
item Smith, Eugene
item LYONS, LESLIE - NATIONAL CANCER INSTITUTE
item Cheng, Hans
item SUCHYTA, STEVEN - MICHIGAN STATE UNIVERSITY

Submitted to: Poultry Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/8/1997
Publication Date: N/A
Citation: N/A

Interpretive Summary: Twenty-two known, functional genes have been placed on the chicken gene map using a defined international reference population that was developed at the Avian Disease and Oncology Laboratory. The location of known genes will contribute to the ordering of the numerous other markers already placed on the map. Identification of these conserved groups of genes will also contribute to comparative gene mapping involving other livestock such as pigs, cattle and sheep. Ultimately, an integrated map with many markers will help to identify genes that are of commercial importance to the poultry industry such as disease resistance and productivity traits.

Technical Abstract: The placement of known genes on linkage maps provides an informative framework for comparative gene mapping. In comparative gene mapping, conserved synteny is broadly defined as groups of two or more linked markers that are also linked in two or more species. Although many anonymous markers have been placed on the chicken genome map, locating known genes will augment the number of conserved syntenic groups and consolidate linkage groups. In this report, 22 additional genes have been assigned to linkage groups or chromosomes; five syntenic groups were identified. Ultimately, conserved syntenic groups may help to pinpoint important quantitative trait loci.