Submitted to: Pathology Research and Practice
Publication Type: Review Article
Publication Acceptance Date: 8/26/1994
Publication Date: N/A
Technical Abstract: Isospora belli is a coccidian parasite of humans with a direct fecal-oral cycle. Humans become infected by ingesting sporulated oocysts with food or water contaminated with human feces. After ingestion of oocysts, sporozoites excyst in intestinal lumen, produce schizonts, gamonts, and unsporulated oocysts are excreted in feces. Presumably, some sporozoites enter extra intestinal tissues and produce unizoite tissue cysts. These unizoite tissue cysts of I. belli are similar in structure to tissue cysts of Isospora species of cats and dogs.