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Title: Certification of elements in and use of standard reference material 3280 multivitamin/multielement tablets

Author
item Turk, G - National Institute Of Standards & Technology (NIST)
item Sharples, K - National Institute Of Standards & Technology (NIST)
item Christopher, S - National Institute Of Standards & Technology (NIST)
item Cleveland, D - National Institute Of Standards & Technology (NIST)
item Day, R - National Institute Of Standards & Technology (NIST)
item Jongsma, C - National Institute Of Standards & Technology (NIST)
item Long, S - National Institute Of Standards & Technology (NIST)
item Mackey, E - National Institute Of Standards & Technology (NIST)
item Marlow, A - National Institute Of Standards & Technology (NIST)
item Oflaz, R - National Institute Of Standards & Technology (NIST)
item Paul, R - National Institute Of Standards & Technology (NIST)
item Sieber, J - National Institute Of Standards & Technology (NIST)
item Thompson, R - National Institute Of Standards & Technology (NIST)
item Wood, L - National Institute Of Standards & Technology (NIST)
item Yu, L - National Institute Of Standards & Technology (NIST)
item Zeisler, R - National Institute Of Standards & Technology (NIST)
item Wise, S - National Institute Of Standards & Technology (NIST)
item Yen, J - National Institute Of Standards & Technology (NIST)
item Atkinson, Renata
item Greene, E - US Department Of Agriculture (USDA)
item Harnly, James - Jim
item Ho, I - Grocery Manufacturers Association (GMA)
item Betz, J - National Institutes Of Health (NIH)

Submitted to: Official Methods of Analysis of AOAC International
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/13/2013
Publication Date: 12/1/2013
Citation: Turk, G.C., Sharples, K.E., Christopher, S.J., Cleveland, D., Day, R.D., Jongsma, C.G., Long, S.E., Mackey, E.A., Marlow, A.F., Oflaz, R., Paul, R.L., Sieber, J.R., Thompson, R.Q., Wood, L.J., Yu, L.L., Zeisler, R., Wise, S.A., Yen, J.H., Atkinson, R.L., Greene, E., Harnly, J.M., Ho, I.P., Betz, J.M. 2013. Certification of elements in and use of standard reference material 3280 multivitamin/multielement tablets. Official Methods of Analysis of AOAC International. 96:1281-1287.

Interpretive Summary: Standard Reference Material (SRM) 3280 Multivitamin/Multielement Tablets was issued by the National Institute of Standards and Technology (NIST) in 2009 and has certified and reference mass fraction values for 13 vitamins, 26 elements, and 2 carotenoids. This paper describes the process by which certified values were determined for the 26 elements. Elements were measured using two or more analytical methods at NIST with additional data contributed by collaborating laboratories. Eight different methods were used in total. Certified values were supplied for 18 elements and reference values were assigned for 8 elelments. 95% confidence intervals were assigned for each element and the homogeneity of the standard was determined. This reference material will allow laboratories to verify the accuracy of their analyses and will improve the quality of the data for dietary supplements.

Technical Abstract: Standard Reference Material (SRM) 3280 Multivitamin/Multielement Tablets was issued by the National Institute of Standards and Technology (NIST) in 2009 and has certified and reference mass fraction values for 13 vitamins, 26 elements, and 2 carotenoids. Elements were measured using two or more analytical methods at NIST with additional data contributed by collaborating laboratories. This reference material is expected to serve a dual purpose: to provide quality assurance in support of a database of dietary supplement products and to provide a means for analysts, dietary supplement manufacturers, and researchers to assess the appropriateness and validity of their analytical methods and the accuracy of their results.