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Title: Correlation between Marek's disease virus replication rates and pathotype based on fifteen virus strains

Author
item Dunn, John

Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/2/2011
Publication Date: 7/16/2011
Citation: Dunn, J.R. 2011. Correlation between Marek's disease virus replication rates and pathotype based on fifteen virus strains [CD-ROM]. American Veterinary Medical Association (AVMA) Convention, July 16-19, 2011, St. Louis, Missouri. Paper No. 11066.

Interpretive Summary:

Technical Abstract: Previous studies have suggested a relationship between replication rates and virulence of Marek's disease virus strains. In most cases, past studies have compared a single vv+MDV strain to a vMDV strain. The purpose of this study was to confirm a correlation between replication rate and pathotype using a broad selection of virus strains. In vivo replication was evaluated for 15 strains, including 5 vMDV (JM/102W, GA/22, 571, 596A, and 617A), 5 vvMDV (Md5, 549A, 568A, 595, and 643P), and 5 vv+MDV strains (584A, 645, 648A, 660A, and 686). Results from qPCR and virus isolation will be discussed.