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Title: Auxin Chemical and Molecular Biology

Author
item HENDRICKSON-CULLER, A.
item QUINT, M.
item Slovin, Janet
item COHEN, J.

Submitted to: Comprehensive Natural Products Chemistry
Publication Type: Book / Chapter
Publication Acceptance Date: 1/20/2009
Publication Date: 5/5/2010
Citation: Hendrickson-Culler, A., Quint, M., Slovin, J.P., Cohen, J. 2010. Auxin Chemical and Molecular Biology. Barton, D. & Meth-Cohn, O. Comprehensive Natural Products Chemistry. Elsevier. 4:9-125.

Interpretive Summary:

Technical Abstract: Auxins function as key regulators at the intersection between developmental and environmental events and the response pathways that they trigger. Naturally occurring members of this hormone group include indole-3-acetic acid (IAA), indole-3-butyric acid (IBA), and 4-chloro-indole-3-acetic acid (4-Cl-IAA. Auxin levels vary dramatically within the plant body and throughout the life cycle of the plant, forming complex gradients that appear to be a central component of its regulatory activity for plant development. Accordingly, plants have evolved intricate networks with adaptive plasticity as well as genetic and biochemical redundancy to regulate auxin levels in specific tissues in response to changing environmental and developmental conditions. Our knowledge about auxin has progressed markedly in many areas over the last several years. Accordingly, this review will focus primarily on the more recent discoveries and their impact on our current understanding of the processes leading to the biosynthesis of auxin, its homeostatic regulation, as well as the mechanisms of auxin perception and subsequent regulation of gene expression.