Submitted to: Current Opinion in Plant Biology
Publication Type: Review Article
Publication Acceptance Date: 10/29/2007
Publication Date: 2/1/2008
Citation: Mitchum,, M.G., Wang, X., Davis,, E.L. 2008. Diverse and conserved roles of CLE peptides. Current Opinion in Plant Biology. 11:75-81.
Technical Abstract: The function of plant CLAVATA3(CLV3)/ENDOSPERM SURROUNDING REGION(ESR)(CLE)peptides in shoot meristem differentiation has been expanded in recent years to implicate roles in root growth and vascular development among different CLE family members. Recent evidence suggests that nematode pathogens within plant roots secrete ligand mimics of plant CLE peptides to modify selected host cells into multinucleate feeding sites. This discovery demonstrated an unprecedented adaptation of an animal gene product to functionally mimic a plant peptide involved in cellular signaling for parasitic benefit. This review highlights the diverse and conserved role of CLE peptides in these different contexts.