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Title: Using the reactive dye method to covalently attach antibacterial compounds to cotton.

Author
item Chun, David
item Gamble, Gary

Submitted to: National Cotton Council Beltwide Cotton Conference
Publication Type: Proceedings
Publication Acceptance Date: 9/29/2006
Publication Date: 6/12/2007
Citation: Chun, D.T., Gamble, G.R. 2007. Using the reactive dye method to covalently attach antibacterial compounds to cotton. National Cotton Council Beltwide Cotton Conference.

Interpretive Summary: Trimethoprim and sulfamethoxazole could be made to behave as reactive dyes which can covalently bind to cotton fabric. The treated cotton fabric becomes imparted with antibacterial properties which appear to persist through multiple laundering. Very likely, this ease of application may extend to the use of other antibiotic drugs to create cotton fabric where tailored or designer antibacterial fabric is desired.

Technical Abstract: The antibacterial compounds used were sulfamethoxazole and trimethoprim. A version of the reactive dye method was used to react these two compounds chemically with the cotton fiber molecule. The two compounds were activated and then covalently bonded to cotton fabric, either separately or together in a 1:1 ratio. The treated fabrics were then assayed for antibacterial properties that may have been imparted by addition of these antibacterial compounds. The anitbacterial assay used was a modification of the "AATCC Test Method 100-1999, Antibacterial Finishes on Textile Materials: Assessment of", which was reported on at the 2006 Beltwide Proceedings. The result of the assay will be reported.