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Title: Genomics of Sex and Sex Chromosomes

item MING, RAY
item Moore, Paul

Submitted to: Current Opinion in Plant Biology
Publication Type: Review Article
Publication Acceptance Date: 1/10/2007
Publication Date: 4/15/2007
Citation: Ming, R., P.H. Moore 2007 Genomics of sex chromosomes. Current Opinion in Plant Biology. 10:123-130.

Interpretive Summary: not applicable

Technical Abstract: Sex chromosomes are distinctive, not only because of their gender determining role, but also for genomic features that reflect their evolutionary history. The genomic sequences in the ancient sex chromosomes of humans and in the incipient sex chromosomes of medaka, stickleback, and papaya exhibit unusual features as consequences of their evolution such as the enormous palindrome structure in human MSY and a duplicated genomic fragment that evolved into a Y chromosome in medaka. Comparative genomic analysis of ancient and incipient sex chromosomes highlights common features that implicate the selection forces that shaped them even though the evolutionary origin, pace, and fate vary widely among individual sex determining systems.