|Picciano, Mary Frances|
|Harnly, James - Jim|
Submitted to: Journal of Food Composition and Analysis
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/7/2007
Publication Date: 5/31/2007
Citation: Dwyer, J.T., Picciano, M., Betz, J.M., Fisher, K.D., Saldanha, L.G., Yetley, E.A., Coates, P.M., Milner, J., Whitted, J., Burt, V., Radimer, K., Wilger, J., Sharpless, K.E., Holden, J.M., Schweitzer, A., Andrews, K., Roseland, J.M., Zhao, C., Harnly, J.M., Wolf, W.R., Perry, C.R. 2007. Progress in developing dietary supplement databases: The analytically validated Dietary Supplement Ingredient Database (DSID) and Dietary Supplement Label Databases (DSLD). Journal of Food Composition and Analysis. Available: doi:10.1016/j.jfca.2007.07.010. Interpretive Summary: Many Americans are acquiring a significant portion of their essential vitamins and minerals from dietary supplements. As a result, the Office of Dietary Supplements (ODS) at the National Institutes of Health has been mandated by Congress with establishing methods and a database for dietary supplements. ODS has contracted with USDA to establish an analytically verified Dietary Supplements Ingredients Database (DSID) and is working with the National Center for Health Statistics to enhance the Dietary Supplement Label Database (DSLD). This paper represents a progress report on these projects.
Technical Abstract: Although an estimated 50% of the US population consumes dietary supplements, analytically substantiated data on bioactive constituents in them are sparse. Several programs funded by the Office of Dietary Supplements (ODS) at the National Institutes of Health enhance dietary supplement database development and help to better describe the quantitative and qualitative contributions of dietary supplements to total dietary intakes. Ultimately, a dietary supplement ingredient database (DSID) will prove useful to professionals in permitting more accurate estimates of the contribution of dietary supplements to total dietary intakes of nutrients, and better evaluating the role of dietary supplements in promoting health and well-being. One initiative is with USDA to develop an analytically substantiated DSID. The products chosen initially for analytical substantiation are adult multivitamin-mineral supplements (often also referred to as "multis" or "multiples"). The rationale is that these products are widely used, a standardized reference material exists, and analytical methods are available for their constituents. Also, they have no standard scientific, regulatory, or marketplace definitions, they have widely varying compositions, characteristics, bioavailability, and bioequivalence of vitamins and minerals, and the extent to which actual amounts deviate from label values is not known. A second effort involves collaboration with the National Center for Health Statistics to enhance the National Health and Nutrition Examination Survey (NHANES) dietary supplement label database for the National Health and Nutrition Examination Survey (DSLD-NHANES). The newest ODS effort explores the feasibility and practicality of developing a database of all dietary supplement labels marketed in the United States (DSLD-USA). This article describes these and supportive projects.