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United States Department of Agriculture

Agricultural Research Service

Title: PHYTOPHTHORA GENOME SEQUENCES UNCOVER EVOLUTIONARY ORIGINS AND MECHANISMS OF PATHOGENESIS)

Author
item Tyler, Brett
item Tripathy, Sucheta
item Xuemin, Zhang
item Dehal, Paramvir
item Jiang, Rays
item Aerts, Andrea
item Arredondo, Felipe
item Baxter, Laura
item Benasson, Douda
item Beynon, Jim
item Damasceno, Cynthia
item Dickerman, Allan
item Dorrance, Anne
item Dou, Daolong
item Dubchak, Inna
item Garbelotto, Matteo
item Gijzen, Mark
item Gordon, Stuart
item Govers, Francine
item Grunwald, Niklaus
item Huang, Wayne
item Ivors, Kelly
item Jones, Richard
item Kamoun, Sophien
item Konstantinos, Krampis
item Lamour, Kurt
item Lee, Mi-kyung
item Mcdonald, W
item Medina, Monica
item Meijer, Harold
item Nordberg, Eric
item Maclean, Donald
item Ospina-giraldo, Manuel
item Morris, Paul
item Phuntumart, Vipaporn
item Putnam, Nicholas
item Rash, Sam
item Rose, Jocelyn
item Sakihama, Yasuko
item Salamov, Asaf
item Savidor, Alon
item Scheuring, Chantel
item Smith, Brian
item Sobral, Bruno
item Terry, Astrid
item Torto-alalibo, Trudy
item Win, Joe
item Xu, Zhanyou
item Zhang, Hongbin
item Grigoriev, Igor
item Rokhsar, Daniel
item Boore, Jeffrey

Submitted to: Science
Publication Type: Peer reviewed journal
Publication Acceptance Date: 7/18/2006
Publication Date: 9/1/2006
Citation: Tyler, B.M., Tripathy, S., Xuemin, Z., Dehal, P., Jiang, R.H., Aerts, A., Arredondo, F., Baxter, L., Benasson, D., Beynon, J.L., Damasceno, C.M., Dickerman, A., Dorrance, A.E., Dou, D., Dubchak, I., Garbelotto, M., Gijzen, M., Gordon, S., Govers, F., Grunwald, N., Huang, W., Ivors, K., Jones, R.W., Kamoun, S., Konstantinos, K., Lamour, K., Lee, M., Mcdonald, W.H., Medina, M., Meijer, H.J., Nordberg, E., Maclean, D.J., Ospina-Giraldo, M.D., Morris, P., Phuntumart, V., Putnam, N., Rash, S., Rose, J.K., Sakihama, Y., Salamov, A., Savidor, A., Scheuring, C., Smith, B., Sobral, B.W., Terry, A., Torto-Alalibo, T., Win, J., Xu, Z., Zhang, H., Grigoriev, I., Rokhsar, D., Boore, J. 2006. Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis. Science. 313:1261-1266.

Interpretive Summary: DNA from two important plant pathogens have been assembled and put in sequence. This allows scientist to compare the two related pathogens with other organisms whose DNA sequence has been determined, and determine evolutionary origins. The two pathogens are responsible for billions of dollars in losses to soybeans, trees and shrubs. The DNA sequence provides a map for determining which genes may be important in causing the diseases that result in large economic and aesthetic losses. This information will be used initially by scientist involved in preventing plant disease.

Technical Abstract: Draft genome sequences of the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum have been determined. Oomycetes such as these Phytophthora species share the kingdom Stramenopiles with photosynthetic algae such as diatoms, and the Phytophthora sequences suggest that the kingdom’s ancestor harbored a photosynthetic endosymbiont. Comparison of the two species’ genomes reveals a rapid expansion and diversification of protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors and in particular a superfamily of 700 proteins with similarity to known oomycete avirulence genes.

Last Modified: 8/24/2016
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