STRUCTURALLY INTEGRATED ORGANIC LIGHT-EMITTING DEVICE (OLED)-BASED SENSORS FOR INDUSTRIAL AND ENVIRONMENTAL SECURITY: SENSORS FOR HYDRAZINE AND ANTHRAX

Authors: SHINAR, RUTH - IOWA STATE UNIVERSITY; ZHOU, ZHAOQUN - IOWA STATE UNIVERSITY; CHOUDHURY, BHASKAR - IOWA STATE UNIVERSITY; Tabatabai, Louisa; SHINAR, JOSEPH - IOWA STATE UNIVERSITY

Submitted to: International Society for Optical Engineering
Publication Type: Abstract Only
Publication Acceptance Date: 4/18/2005
Publication Date: 10/24/2005
Citation: Shinar, R., Zhou, Z., Choudhury, B., Tabatabai, L.B., Shinar, J. 2005. Structurally integrated organic light-emitting device (oled)-based sensors for industrial and environmental security: sensors for hydrazine and anthrax. International Society for Optical Engineering. 5588:59-69.

Interpretive Summary:

Technical Abstract: The application of the new, compact platform of structurally integrated, luminescent (bio)chemical sensors, where the photoluminescence (PL) excitation source is an OLED, to the detection of hydrazine and anthrax is described. The hydrazine sensor is based on the reaction between nonluminescent anthracene-2,3-dicarboxaldehyde and hydrazine or hydrazine sulfate, which generates a luminescent product. The anthrax sensor is based on a Forster resonance energy transfer (FRET) assay, where the anthrax-secreted lethal factor enzyme cleaves certain labeled peptides at a specific site. The cleaving separates the FRET donor-acceptor pair, resulting in an increase in the PL of the donor, which was previously absorbed by the acceptor. The use of OLED pixels in sensor arrays for multianalyte detection is also described.