Submitted to: Meeting Abstract
Publication Type: Proceedings
Publication Acceptance Date: 11/18/2004
Publication Date: 11/19/2004
Citation: Fadly, A.M. 2004. Neoplastic diseases of chickens: Marek's disease and avian leukosis. In: Proceedings of International Symposium on Avian Immunology. ANECA, November 18-20, 2004, Queretaro, Mexico. 2004 CDROM. p. 57-59. Interpretive Summary:
Technical Abstract: Virus-induced neoplastic diseases of chickens are caused by either a retrovirus (leukosis/sarcoma, reticuloendotheliosis) or by herpesvirus, Mareks disease (MD). The leukosis/sarcoma (L/S) viruses are avian retroviruses that infect chickens. Lymphoid leukosis (LL), a B-cell lymphoma of chickens is the most common form of leukosis that arise from infection with avian leukosis virus (ALV). However, in the early 1990's, myelocytomatosis was recognized as a neoplastic condition that is frequently detected in meat-type chickens infected subgroup J ALV. On the other hand, MD, an economically important lymphoproliferative disease of primarily chickens, is caused by an alphaherpesvirus. This presentation is primarily focused on MD and includes discussion of: a) current strategies for diagnosis and control of MD; b) need for continued research efforts; and c) future strategies for better control of the disease.