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United States Department of Agriculture

Agricultural Research Service

Title: ARTEMISIA ANNUA AS A TRADITIONAL HERBAL ANTIMALARIAL)

Author
item Wilcox, Merlin
item Bodeker, Gerard
item Bourdy, Genevieve
item Dhingra, Vikas
item Falquet, Jacques
item Ferreira, Jorge
item Graz, Bertrand
item Hirt, Hans-martin
item Hsu, Elisabeth
item De Magalhaes, Pedro
item Provendier, Damien
item Wright, Colin

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 2/1/2004
Publication Date: 6/1/2004
Citation: Wilcox, M., Bodeker, G., Bourdy, G., Dhingra, V., Falquet, J., Ferreira, J.F., Graz, B., Hirt, H., Hsu, E., De Magalhaes, P.M., Provendier, D., Wright, C. 2004. Artemisia annua as a traditional herbal antimalarial. In: Wilcox, M.L., Bodeker, G., Rasoanaivo, editors. Traditional Medicinal Plants and Malaria, Boca Raton, FL: CRC Press. 4: 43-59.

Interpretive Summary:

Technical Abstract: Artemisinin is the only natural antimalarial after quinine and is currently used in over 100 countries to fight chloroquine-resistant Plasmodium falciparum. Because artemisinin synthesis produces final yields lower than 4%, Artemisia annua is the only commercial source of the compound. Artemisia annua is also being considered for traditional antimalarial use as a tea. This work reviews the ethnopharmacology, clinical efficacy, evolution of resistance, safety, and tolerability of artemisinin and its related antimalarials as well as some points about the cultivation of A. annua and its public health potentials if used as a traditional herbal antimalarial. This review aims to explore the possibilities on the supervised and responsible cultivation and use of Artemisia annua as a traditional preparation (tea) by the poor people of Africa, who cannot afford current antimalarials produced by pharmaceutical companies.

Last Modified: 8/24/2016
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