Submitted to: Patent Application
Publication Type: Abstract Only
Publication Acceptance Date: 12/20/2001
Publication Date: 6/20/2003
Citation: TATUM, F.M., BRIGGS, R.E. TEMPERATURE SENSITIVE PLASMIDS OF P. HAEMOLYTICA. 2003. U.S. PATENT 6,573,093.
Technical Abstract: Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are not reverting and contain no foreign DNA and no introduced antibiotic resistance genes.