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ARS Home » Research » Publications at this Location » Publication #134098
Title: CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN

Author
item OKARMURA, MASASHI - 1265-40-00
item Lillehoj, Hyun
item BABU, UMA - FDA
item RAYBOURNE, RICHARD - FDA
item HECKERT, ROBERT - VA-MD REG COL. VET MED

Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 5/1/2002
Publication Date: 5/1/2003
Citation: OKARMURA, M., LILLEHOJ, H.S., BABU, U.S., RAYBOURNE, R.B., HECKERT, R.A. CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN. AMERICAN VETERINARY MEDICAL ASSOCIATION ABSTRACT. 2003.

Interpretive Summary:

Technical Abstract: The effects of Salmonella enteritidis vaccination on the host cellular immune response was evaluated. Chickens were vaccinated subcutaneously with killed S. enteritidis vaccine at the ages of 3 and 5 weeks. After vaccination, serum samples were collected for 3 weeks for the evaluation of IFN- and IL-2 levels. The IFN- level was significantly (p<0.05) higher in the vaccine group at 7, 11, 14, and 21 days post vaccination (dpv) whereas the IL-2 level was higher at 14, 18, and 21 dpv. Therefore, killed S. enteritidis vaccine induce important chicken cytokines which are involved in the elimination of the intracellular Salmonella.