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ARS Home » Research » Publications at this Location » Publication #127770
Title: IMMUNE FUNCTION FOLLOWING VACCINATION WITH AN INACTIVATED AVIAN PNEUMOVIRUS VACCINE

Author
item Kapczynski, Darrell
item Tumpey, Terrence

Submitted to: Western Poultry Disease Conference
Publication Type: Abstract Only
Publication Acceptance Date: 12/20/2001
Publication Date: 5/5/2002
Citation: N/A

Interpretive Summary:

Technical Abstract: Avian pneumovirus (APV) is the causative agent of turkey rhinotracheitis (TRT) which results in primarily a respiratory disease. Previous research in our lab indicates that inactivated APV vaccines do not induce serum virus-neutralizing antibodies and are not protective. The objective of this study was to compare cellular immune mechanisms of purified turkey lymphocytes from control and immunized birds. The effect of APV infection on the avian immune system was examined by comparing APV-specific serum and local IgG, IgM or IgA antibodies following virus challenge.