Submitted to: Cytogenetics and Cell Genetics
Publication Type: Review Article
Publication Acceptance Date: 10/13/2000
Publication Date: N/A
Citation: Interpretive Summary:
Technical Abstract: The aim of this report was to summarize the progress made in the last eight years. Through the efforts of 34 authors in 21 departments, we have produced a report reviewing the current status of genomics in the chicken and other birds. This review summarizes some successes that have highlighted to the wider scientific community the value of the chicken as a model species. Progress on the genetic and physical mapping of the chicken has come a long way; even the problem of identification of microchromosomes has been overcome by physical mapping methods. New tools open the way to examine the evolution, not only of avian genomes but also of other vertebrates. Analysis of the comparative map between chicken, mouse and human built on the gene mapping efforts of the chicken mapping community, provided new insights into the evolution of the vertebrate genome. The accumulation of over 20,000 chicken ESTs marks a new phase in the exploration of the avian genome and its function. We hope this review will be of interest and direct benefit not only to those in the poultry industry, but also to those in other fields, such as, medicine and developmental biology.