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Title: SEROLOGIC REACTIVITY CORRELATES WITH PHYLOGENETIC ANALYSIS OF ADENOVIRUS HEXON GENE REGION (POSTER FOR AMERICAN SOC. FOR VIROLOGY MEET., JULY 2000)

Author
item Lehmkuhl, Howard
item Hobbs, Lea

Submitted to: American Society for Virology Meeting
Publication Type: Abstract Only
Publication Acceptance Date: 7/10/2000
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: The Adenovirus Study Group of the International Committee on Taxonomy of Viruses has proposed a new genus, Atadenovirus, in the family Adenoviridae. Ovine adenovirus isolate 287 has been designated as the type species because it was the first fully sequenced member of the new genus. The study group also proposed the use of phylogenetic analysis based primarily on protease and hexon amino acid sequence comparisons as a characteristic for species designation within the genus. The purpose of this study was to compare new goat and deer adenoviruses whose serologic cross reactivity with members of the Atadenovirus genus suggested they were also potential members of the proposed genus. Primers were generated to amplify an approximate 2700 bp region internally in the hexon gene region. Phylogenetic analysis of the hexon amino acid sequence indicated that the deer and goat adenoviruses are members of the Atadenovirus genus.