|VAN CAMPEN, HANA|
Submitted to: Wildlife Disease Association Annual Meeting
Publication Type: Abstract Only
Publication Acceptance Date: 7/6/2000
Publication Date: N/A
Technical Abstract: Severe pulmonary edema and hemorrhagic typhlocolitis resulted in the acute death of a recently captured 6-month old moose calf at the Wyoming Game and Fish Department's Sybille Wildlife Research and Conservation Education Unit near Wheatland, Wyoming. Histologically there was massive pulmonary edema associated with acute vasculitis and the presence of large intranuclear inclusion bodies in endothelium. Similar vasculitis and viral inclusions were present in the submucosa and muscularis of the cecum and colon. Viral particles, typical of adenovirus, were observed by negative stain electron microscopy in tissues from the calf. Adenovirus was isolated in culture on white-tailed deer umbilical endothelial cells. This virus was identical by serologic and restriction enzyme analysis to adenoviruses isolated from black-tailed and mule deer (Odocoileus hemionus columbianus, O. hemionus hemionus) and white-tailed deer (O. virginianus) from California and Iowa, respectively. The clinical and pathologic features of systemic adenoviral infection in this moose calf were consistent with the lesions described in adenoviral hemorrhagic disease in black-tailed deer in California. No other cervids at Sybille developed a similar disease, and the source of the virus for the moose calf is not known.