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528 publication requests found.
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Low-cost grain sorting technologies to reduce mycotoxin contamination in maize and groundnut
The widespread contamination of foods by mycotoxins is a public health hazard in sub-Saharan Africa, with maize and groundnut being the major sources of contamination. This study was undertaken to assess the hypothesis that grain sorting can be used to reduce mycotoxin contamination in grain lots by...
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Fusarium pathogenomics and population-specific differences during wheat infection
Fusarium graminearum (Fg) is the primary fungal pathogen responsible for Fusarium head blight (FHB), a devastating disease of wheat and barley worldwide. FHB reduces crop yield and contaminates grain with trichothecene mycotoxins that are harmful to plant, human and animal health. To elucidate popul...
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Changes in wheat nutritional content at elevated [CO2] alter Fusarium graminearum growth and mycotoxin production on grain
Rising atmospheric [CO2] has been shown to impact plant primary metabolism and the severity of Fusarium head
blight (FHB) in wheat. In this study, we evaluated how changes in grain nutritional content due to growth at elevated [CO2] affected
Fusarium graminearum growth and mycotoxin production. Susc...
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Evaluation of flow injection mass spectrometry approach for rapid screening of selected pesticides and mycotoxins in grain and animal feed samples
A fast screening approach for simultaneous detection of twelve pesticides and seven mycotoxins in food and feed samples using flow injection (FI) mass spectrometry (MS) was developed and evaluated. Ten selected pesticides represented five pairs of structural isomers to challenge their MS differentia...
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Analytical challenges associated with detection of emerging, masked, and modified mycotoxins
All mycotoxins were, at one time, “emerging” toxins. Those toxins that were identified many years ago, such as the aflatoxins, deoxynivalenol, ochratoxin A, zearalenone, and the fumonisins, have each been associated with diseases in humans or domestic animals. Over time the tools of both analytical ...
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Self-protection against the sphingolipid biosynthesis inhibitor fumonisin B1 is conferred by a FUM cluster-encoded ceramide synthase
Fumonisin (FB) mycotoxins are produced by some species of the fungus Fusarium and have detrimental effects on human and animal health through their ability to inhibit the sphingolipid biosynthetic enzyme ceramide synthase (CS). Because sphingolipids are an essential component of eukaryotic cells, FB...
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Genomic prediction for resistance to fusarium ear rot and fumonisin contamination in maize
Fusarium ear rot (FER) disease of maize (Zea mays L.) is caused by Fusarium verticillioides (Sacc.) Nirenberg, which produces fumonisin (FUM), a mycotoxin linked to human and animal health risks. Extensive field trials, laborious inoculations and ear evaluations, and expensive antibody assays are re...
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Evolution of secondary metabolite diversity in fungi
Fungi produce thousands of secondary metabolites (SMs) that are diverse in chemical structure and biological activity. SMs produced by plant pathogenic species of Fusarium include pigments, plant hormones, and some of the mycotoxins of greatest concern to agricultural production and food safety. Che...
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Genus-wide analysis of Fusarium polyketide synthases uncovers broad natural product potential
Collectively, species of Fusarium cause economically important diseases on virtually all crop plants, and many species produce secondary metabolites (SMs) that are toxic to animals (i.e., mycotoxins) and can accumulate in crops where they pose health risks to humans, livestock, and pets. Polyketide...
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Vibrio gazogenes-dependent disruption of aflatoxin biosynthesis in Aspergillus flavus: the connection with endosomal uptake and hyphal morphogenesis
Aflatoxin is a liver carcinogen, mycotoxin, and a secondary metabolite that is produced by some plant pathogens within the genus Aspergillus when they infect crops such as corn, peanuts, and cotton. Given the significant adverse health and economic impacts of aflatoxin and a predicted rise of crop c...
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Moderately resistant wheat cultivars lose nutritional quality at elevated CO2 altering Fusarium graminearum growth and mycotoxin production
Increased photosynthetic carbon assimilation rate in C3 crops, such as wheat, at elevated atmospheric CO2 concentrations can dramatically alter grain nutritional quality. Typically, growth at elevated CO2 leads to grain with higher carbohydrate content which in turn also significantly alters the pro...
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Stenotrophomonas bacteria readily colonizes Fusarium graminearum perithecia and reduces perithecia formation
Fusarium graminearum (Fg) is the primary fungal pathogen responsible for Fusarium head blight (FHB), a devastating disease of wheat and barley worldwide. In regions where Fusarium inoculum is limited, the severity of FHB epidemics and accumulation of trichothecene mycotoxins in grain is strongly dri...
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Degradation of aflatoxins B1 by atoxigenic Aspergillus flavus biocontrol agents
Aflatoxins are potent Aspergillus mycotoxins that contaminate food and feed, thereby impacting health and trade. Biopesticides with atoxigenic Aspergillus flavus isolates as active ingredients are used to reduce aflatoxin contamination in crops. The mechanism of aflatoxin biocontrol is primarily att...
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Developments in mycotoxin analysis: an update for 2018-19
This review summarizes developments on the analysis of various matrices for mycotoxins that have been published in the period from mid-2018 to mid-2019. Analytical methods to determine aflatoxins, Alternaria toxins, ergot alkaloids, fumonisins, ochratoxins, patulin, trichothecenes, and zearalenone a...
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Development and characterization of monoclonal antibodies for the mycotoxin citreoviridin
Citreoviridin (CTV) in an inhibitor of mitochondrial ATPase. It has been isolated from molded (yellow) rice and linked to the human disease Shoshin-Kakke (acute cardiac beriberi). Purified CTV can reproduce the symptoms in experimental animals. Beriberi is caused by thiamine deficiency, and the link...
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FVSTUA is a Key Regulator of Sporulation, Toxin Synthesis and Virulence in Fusarium verticillioides
Fusarium verticillioides is one of the most important pathogens of maize, causing rots and producing fumonisin mycotoxins during infection. Ingestion of fumonisin-contaminated corn causes underperformance and even fatal toxicity in livestock and is associated with neural tube birth defects, growth s...
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Genetic diversity and mycotoxin production among Fusarium head blight isolates belonging to the Fusarium tricinctum species complex from Italy
Fusarium head blight (FHB) is a worldwide cereal disease caused by a complex of Fusarium species resulting in high yield losses, reduction in quality and mycotoxin contamination of grain. In Europe, the principal species responsible for FHB are F. graminearum, F. culmorum and F. poae. However, membe...
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Detection of mycotoxins and toxigenic fungi in cereal grains using vibrational spectroscopic techniques: A review
Nutrition-rich cereal grains and oil seeds are the major sources of food and feed for human and livestock, respectively. Infected by fungi and contaminated with mycotoxins are serious problems worldwide for cereals and oil seeds before and after harvest. The growth and development activities of fung...
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Regional and field-specific differences in Fusarium species and mycotoxins associated with blighted North Carolina wheat
Worldwide, while Fusarium graminearum is the main causal species of Fusarium head blight (FHB) in small-grain cereals, a diversity of FHB-causing species belonging to different species complexes has been found in most countries. In the U.S., FHB surveys have focused on the Fusarium graminearum spec...
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Intrapopulation antagonism can reduce the growth and aggressiveness of the wheat head blight pathogen Fusarium graminearum
Fusarium graminearum is a causal agent of Fusarium head blight (FHB), a disease that reduces yield and quality of cereal crops and contaminates grain with mycotoxins that pose health risks to humans and livestock. Interpopulation antagonistic interactions between isolates that produce different tric...
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