Location: Office of The Area Director
Project Number: 6001-51000-003-03-S
Project Type: Non-Assistance Cooperative Agreement
Start Date: Sep 1, 2012
End Date: Aug 31, 2017
This SCA involves three separate research projects with specific objectives as detailed below: “Obesity Prevention in the Mississipi Delta Region of Mississippi” (1) Evaluate a church-based intervention program “Delta Body and Soul” to increase adherence to Dietary Guidelines for Americans (DGA) diet and physical activity recommendations; and (2) serve as a nutritional consultant in the development, implementation, and evaluation of a project designed to improve maternal and neonatal/infant metabolic health and weight outcomes via education of the mothers. “Dietary Intake Patterns Associated with Excess Adiposity in U.S. Children” Using three dietary pattern identification methods, Healthy Eating Index (HEI) 2005, principal component analysis, and reduced rank regression, determine associations among the dietary pattern scores, excess adiposity, physical activity, and sedentary behavior in 2-18 year old U.S. children using the most recent National Health and Nutrition Examination Survey (NHANES) data. “Maternal Obesity, Mediterranean Diet, and Iron Status" (1) Conduct a pilot Mediterranean diet interventin in pregnant obese women; (2) determine the feasibility and acceptability of the intervention; and (3) explore relationships among Mediterranean diet adherence, systemic inflammation, and maternal iron bioavailability.
“Obesity Prevention in the Mississipi Delta Region of Mississippi” Statistical methods will be used to compare changes in diet and physical activity outcomes between the Delta Body and Soul control and intervention participants while accounting for group (church) randomization as well as sociodemographic covariates. An existing education program, Parents as Teachers, will be enhanced to specifically address nutritional prenatal and postnatal topics (e.g. breast-feeding) for mothers and their infants. Statistical methods will also be used to compare health outcomes between mothers and their infants in the standard vs. the enhanced education programs. “Dietary Intake Patterns Associated with Excess Adiposity in U.S. Children” Individual foods consumed by children in the National Health and Nutrition Examination Survey (NHANES) datasets will be assigned to defined food groups based on previous research and investigators’ interest in specific foods. Statistical methods will be used to identify dietary patterns in the NHANES datasets using three different approaches -- Healthy Eating Index (HEI)-2005, principal component analysis, and reduced rank regression. Statistical methods will be used to determine associations among the dietary pattern scores, excess adiposity, physical activity, and sedentary behavior. “Maternal Obesity, Mediterranean Diet, and Iron Status: Approximately 50 pregnant, obese women with mild to moderate anemia will be recruited. Women will be randomized to an active intervention (Mediterranean diet) or attention control condtion between 28-36 weeks gestation. Feasibility will be tracked throughout the study and acceptability of the intervention will be assessed through surveys and interviews post intervention. Dietary intake and biomarkers of systemic inflammation and iron bioavailability will be assessed at baseline and post study.