Page Banner

United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: A NOVEL APPROACH FOR PREDICTING TRANSLATIONAL EFFICIENCY FOR RECOMBINANT GENE EXPRESSION

Location: Food Science Research

Project Number: 6070-41000-008-08-N
Project Type: Non-Funded Cooperative Agreement

Start Date: Feb 1, 2011
End Date: Jan 31, 2016

Objective:
To develop and test models for predicting and controlling translational efficiency of gene expression, and to design and carry out experiments to validate model predictions.

Approach:
Computer models will be developed using free energy of ribosome binding as a factor in translational efficiency. Models will be tested with collaborators using recombinant plasmids in Escherichia coli.

Last Modified: 2/23/2016
Footer Content Back to Top of Page