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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Food Components and Health Laboratory » Research » Research Project #426315

Research Project: Absorption, Metabolism, and Health Impacts of Bioactive Food Components

Location: Food Components and Health Laboratory

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by Ultra-high Performance Liquid Chromatography High-Resolution Mass Spectrometry Reprint Icon - (Peer Reviewed Journal)
Liu, Z., Teng, Z., Pearlstein, D.J., Chen, P., Yu, L., Zhou, B., Luo, Y., Sun, J. 2022. Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by ultra-high performance liquid chromatography high-resolution mass spectrometry. ACS Food Science and Technology. 2(9):1483–1494. https://doi.org/10.1021/acsfoodscitech.2c00193.

Dietary intakes of flavan-3-ols and cardiometabolic health: systematic review and meta-analysis of randomized trials and prospective cohort studies Reprint Icon - (Peer Reviewed Journal)
Raman, G., Avendano, E., Chen, S., Wang, J., Matson, J., Gayer, B., Novotny, J.A., Cassidy, A. 2019. Dietary intakes of flavan-3-ols and cardiometabolic health: systematic review and meta-analysis of randomized trials and prospective cohort studies. American Journal of Clinical Nutrition. 110:1067-1078. https://doi.org/10.1093/ajcn/nqz178.

Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults Reprint Icon - (Peer Reviewed Journal)
Angiletta, C.J., Griffin, L.E., Steele, C.N., Baer, D.J., Novotny, J., Davy, K.P., Neilson, A.P. 2018. Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults. Food & Function. 9:5350-5361. https://doi.org/10.1039/C8FO00962G.

Broccoli consumption affects the human gastrointestinal microbiota Reprint Icon - (Peer Reviewed Journal)
Kaczmarek, J.L., Liu, X., Charron, C.S., Novotny, J., Jeffery, E.H., Seifried, H.E., Ross, S.A., Miller, M.J., Swanson, K.S., Holscher, H.D. 2019. Broccoli consumption affects the human gastrointestinal microbiota. Journal of Nutritional Biochemistry. 63:27-34. https://doi.org/10.1016/j.jnutbio.2018.09.015.

Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of body mass index and daily consumption Reprint Icon - (Peer Reviewed Journal)
Charron, C.S., Vinyard, B.T., Ross, S., Seifried, H., Jeffrey, E., Novotny, J. 2018. Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of body mass index and daily consumption. British Journal of Nutrition. 120:1370-1379. https://doi.org/10.1017/S0007114518002921.

Blackberry feeding increases fat oxidation and improves insulin sensitivity in overweight and obese males Reprint Icon - (Peer Reviewed Journal)
Solverson, P.M., Rumpler, W.V., Leger, J.L., Redan, B.W., Ferruzzi, M.G., Baer, D.J., Castonguay, T.W., Novotny, J. 2018. Blackberry feeding increases fat oxidation and improves insulin sensitivity in overweight and obese males. Nutrients. 10. https://doi.org/10.3390/nu10081048.

Limited appearance of apocarotenoids is observed in plasma after consumption of tomato juices: a randomized human clinical trial Reprint Icon - (Peer Reviewed Journal)
Cooperstone, J.L., Novotny, J., Riedl, K.M., Cichon, M.J., Francis, D.M., Curley, R.W., Schwartz, S.J., Harrison, E.H. 2018. Limited appearance of apocarotenoids is observed in plasma after consumption of tomato juices: a randomized human clinical trial. American Journal of Clinical Nutrition. 108:784-792. https://doi.org/10.1093/ajcn/nqy177.

Dietary intakes of flavan-3-ols and cardiovascular health: a field synopsis using evidence mapping of randomized trials and prospective cohort studies Reprint Icon - (Peer Reviewed Journal)
Raman, G., Shams-White, M., Avendano, E., Chen, F., Novotny, J., Cassidy, A. 2018. Dietary intakes of flavan-3-ols and cardiovascular health: a field synopsis using evidence mapping of randomized trials and prospective cohort studies. Systematic Reviews. 7. https://doi.org/10.1186/s13643-018-0764-z.

Vitamin A Reprint Icon - (Review Article)
Debelo, H., Novotny, J.A., Ferruzzi, M.G. 2017. Vitamin A. Advances in Nutrition. 8:992-994. https://doi.org/10.3945/an.116.014720.

The effects of 100% wild blueberry (Vaccinium angustifolium) juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes Reprint Icon - (Peer Reviewed Journal)
Stote, K.S., Sweeney, M.I., Kean, T., Baer, D.J., Novotny, J., Shakerley, N.L., Chandrasekaran, A., Carrico, P., Melendez, J.A., Gottschall-Pass, K.T. 2017. The effects of 100% wild blueberry (Vaccinium angustifolium) juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes. Biomed Central (BMC) Nutrition. 3. https://doi.org/10.1186/s40795-017-0164-0.

The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans Reprint Icon - (Peer Reviewed Journal)
Novotny, J., Chen, T., Terekhov, A., Gebauer, S.K., Baer, D.J., Ho, L., Pasinetti, G., Ferruzzi, M.G. 2017. The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans. Molecular Nutrition and Food Research. 61. https://doi.org/10.1002/mnfr.201700043.

Adaptation in Caco-2 human intestinal cell differentiation and phenolic transport with chronic exposure to phenolic-rich blackberry (Rubus sp.) extract - (Peer Reviewed Journal)
Redan, B.W., Albaugh, G.P., Charron, C.S., Novotny, J.A., Ferruzzi, M.G. 2017. Adaptation in Caco-2 human intestinal cell differentiation and phenolic transport with chronic exposure to phenolic-rich blackberry (Rubus sp.) extract. Journal of Agricultural and Food Chemistry. 65:2694-2701.

Altered transport and metabolism of phenolic compounds in obesity and diabetes: implications for functional food development and assessment - (Peer Reviewed Journal)
Redan, B.W., Buhman, K.K., Novotny, J.A., Ferruzzi, M.G. 2016. Altered transport and metabolism of phenolic compounds in obesity and diabetes: Implications for functional food development and assessment. Advances in Nutrition. 7:1090-1104.

A single meal containing raw, crushed garlic influences expression of immunity- and cancer-related genes in whole blood of humans - (Peer Reviewed Journal)
Charron, C.S., Dawson, H.D., Albaugh, G.P., Solverson, P.M., Vinyard, B.T., Solano Aguilar, G., Molokin, A., Novotny Dura, J. 2015. A single meal containing raw, crushed garlic influences expression of immunity- and cancer-related genes in whole blood of humans. Journal of Nutrition. 145:2448-2455.

The impact of cranberries on gut microbiota and cardiometabolic health: proceedings of the cranberry health research conference - (Peer Reviewed Journal)
Blumberg, J.B., Basu, A., Krueger, C.G., Lila, M.A., Neto, C.C., Novotny, J., Reed, J.D., Rodriguez-Mateos, A., Toner, C.D. 2016. The impact of cranberries on gut microbiota and cardiometabolic health: Proceedings of the cranberry health research conference. Advances in Nutrition. 7:759-770.

Current capabilities and limitations of the stable isotope technologies and applied mathematical equations in determining whole body vitamin A status - (Peer Reviewed Journal)
Lietz, G., Furr, H., Gannon, B., Green, M., Haskell, M., Lopez-Teros, V., Novotny, J.A., Palmer, A., Russell, R., Tanumihardjo, S. 2016. Current capabilities and limitations of the stable isotope technologies and applied mathematical equations in determining whole body vitamin A status. Food and Nutrition Bulletin. 37:S87-S103.

Absorption and distribution kinetics of the 13C-labeled tomato carotenoid phytoene in healthy adults - (Peer Reviewed Journal)
Moran, N.E., Novotny Dura, J., Cichon, M., Riedl, K., Rogers, R., Grainger, E., Schwartz, S., Erdman, J., Clinton, S. 2016. Absorption and distribution kinetics of the 13C-labeled tomato carotenoid phytoene in healthy adults. Journal of Nutrition. 146:368-376.

Compartmental and noncompartmental modeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults - (Peer Reviewed Journal)
Moran, N.E., Cichon, M., Riedl, K., Grainger, E., Schwartz, S., Novotny Dura, J., Erdman, J., Clinton, S. 2015. Compartmental and noncompartmental modeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults. American Journal of Clinical Nutrition. 102:1436-1449.

Separation of lipoproteins for quantitative analysis of 14C-labeled lipid soluble compounds - (Peer Reviewed Journal)