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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Research

Research Programs and Projects at this Location

ARS research is organized into National Programs. Within each National Program are research projects. Listed below are  the National Programs and research projects currently conducted at this location.

Clicking on a National Program (NP) will take you  to the main ARS site for more information on the program. Clicking on a research  project title will take you to more information on the project.


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Animal Health (NP #103)
Characterization of Antigens, Virulence Markers, and Host Immunity in the Pathogenesis of Johne’s Disease
(In-House Appropriated)
Characterization of the Pathogenesis and Antigen Expression in Spirochete Diseases
(In-House Appropriated)
Characterize the Immunopathogenesis and Develop Diagnostic and Mitigation Strategies to Control Tuberculosis in Cattle and Wildlife
(In-House Appropriated)
Identification of Disease Mechanisms and Control Strategies for Bacterial Respiratory Pathogens in Ruminants
(In-House Appropriated)
Identification of Disease Mechanisms and Control Strategies for Viral Respiratory Pathogens of Ruminants
(In-House Appropriated)
Intervention Strategies to Control Endemic and New and Emerging Viral Diseases of Swine
(In-House Appropriated)
Intervention Strategies to Control Influenza A Virus Infection in Swine
(In-House Appropriated)
Non-antibiotic Approaches to Control Mastitis
(In-House Appropriated)
Non-Antibiotic Strategies to Control Priority Bacterial Infections in Swine
(In-House Appropriated)
Pathobiology, Genetics, and Detection of Transmissible Spongiform Encephalopathies
(In-House Appropriated)
Pathogenesis and Development of Improved Diagnostic and Control Strategies for Brucellosis in Livestock and Wildlife
(In-House Appropriated)
Characterization of the Evolution of Influenza A Viruses (IAV) in Swine
(Cooperative Agreement)
Characterization of Virus Isolates in Support of Swine Influenza A Virus Surveillance and Diagnostics
(Cooperative Agreement)
ARS Streptococcus Equi Ssp. Zooepidemicus Challenge Study
(Interagency Reimbursable Agreement)
Characterization of the Evolution of Influenza A Viruses (IAV) in Swine and Pathotyping of IAV in the Natural Host
(Interagency Reimbursable Agreement)
Characterization of Virus Isolates from the USDA Swine Influenza A Virus Surveillance System
(Interagency Reimbursable Agreement)
Continued Development of Antibodies for Bottlenose Dolphin Immune Assays
(Interagency Reimbursable Agreement)
Continued Development of Antibodies for Bottlenose Dolphin Immune Assays
(Interagency Reimbursable Agreement)
Rapid Evolution of Influenza A Viruses in Swine Results in Zoonotic Viruses with Human Pandemic Potential
(Interagency Reimbursable Agreement)
The Ecology of Seneca Virus A in U.S. Swine Marketing Chain
(Interagency Reimbursable Agreement)
The Study of Influenza A Viruses in the Swine Host
(Interagency Reimbursable Agreement)
USDA Influenza A Virus in Swine Surveillance System – Genomic Epidemiology and Evolution
(Interagency Reimbursable Agreement)
USDA Swine Influenza Virus Surveillance System: Computational Evolutionary Biology of Whole Genome Sequences - Continuation
(Interagency Reimbursable Agreement)
Survival of the Animal Pathogen Bordetella bronchiseptica in Aerosols
(Non-Funded Cooperative Agreement)
Alternate Iron Regulatory Pathways in Mycobacterium Avium subsp. Paratuberculosis
(Reimbursable Cooperative Agreement)
Cell Based Therapeutic Approach for Immunomodulation of Inflammatory Response for a Better Outcome in Dairy Animals with Mastitis
(Reimbursable Cooperative Agreement)
Comparative Genomic Assessment of the Evolution and Zoonotic Potential of MRSA ST5 Strains Isolated from Humans Living in US Swine Producing Regions
(Reimbursable Cooperative Agreement)
Development and Testing of Mycobacterium Avium Subsp. Paratuberculosis Diva Vaccines in Dairy Cattle
(Reimbursable Cooperative Agreement)
Generation of Zoonotic Influenza Resistant Recombinant Pigs via Site-Directed Technology
(Reimbursable Cooperative Agreement)
Identification of Proteins Involved in Cross Protective Immune Responses as a Mechanisms for Broadly Protective Bacterial Vaccine Development
(Reimbursable Cooperative Agreement)
Role of the Viral Ovarian Domain Protease in PRRSV Pathogenesis
(Reimbursable Cooperative Agreement)
Control of Swine Influenza Through Antigenic Characterization and Improved Vaccines
(Non-Assistance Cooperative Agreement)
Development of a Transgenic Mouse that Expresses the Bovine Prion Polymorphism T231
(Non-Assistance Cooperative Agreement)
Investigate the Pathogenesis and Biology of Emerging and Re-Emerging Swine Viral Diseases
(Non-Assistance Cooperative Agreement)
Investigation of a PRNP Polymorphism on Susceptibility to Bovine Spongiform Encephalopathy (BSE)
(Non-Assistance Cooperative Agreement)
Population Immunity Assessed by Antibody Landscaping as Defined by Antigenic Evolution of Influenza A Viruses (IAV) in Swine
(Non-Assistance Cooperative Agreement)
Production of Monoclonal Antibodies to Swine Viruses
(Non-Assistance Cooperative Agreement)
Role of N-Linked Glycosylation in the In Transmission and Differentiation of CWD Prions
(Non-Assistance Cooperative Agreement)
Swine Coronavirus Molecular Research Targeting Nonstructural Proteins and Development of Novel Vaccines
(Non-Assistance Cooperative Agreement)
Food Safety, (Animal and Plant Products) (NP #108)
Analysis of Virulence and Antibiotic Resistance Mechanisms of Salmonella and Development of Intervention Strategies
(In-House Appropriated)
Characterization of Colonization of Shiga Toxin-producing Escherichia coli (STEC) in Cattle and Strategies for Effective Preharvest Control
(In-House Appropriated)
Intestinal Microbial Ecology and Metagenomic Strategies to Reduce Antibiotic Resistance and Foodborne Pathogens
(In-House Appropriated)
Alternatives to Antibiotics: Neonatal Immunomodulation to Improve Disease Resistance in Animals
(Cooperative Agreement)
Alternatives to Antibiotics: Neonatal Immunomodulation to Improve Disease Resistance in Animals
(Interagency Reimbursable Agreement)
Effects of Commensal Bacteria on the Ecology and Development of the Chicken Intestinal Tract
(Non-Funded Cooperative Agreement)
Computational Analysis of Host, Bacteria, and Microbiome for Development of Strategies to Enhance Health and Food Safety
(Non-Assistance Cooperative Agreement)
Immune Assay to Evaluate Cross-Protection Following Influenza Virus Vaccination
(Trust Fund Cooperative Agreement)