Aida Elizabeth Rieder
(Elizabeth) (PhD)
Foreign Animal Disease Research
Research Microbiologist
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Fax:
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Publications
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Understanding the molecular mechanisms of attenuation in codon deoptimized FMDV strains
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Medina, G.N., Spinard Iii, E.J., Azzinaro, P.A., Rodriguez-Calzada, M., Rieder, A.E., Diaz San Segundo, F.C., De Los Santos, T.B. 2023. Understanding the molecular mechanisms of attenuation in codon deoptimized FMDV strains. Meeting Abstract. https://doi.org/10.3390/v15061332.
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Deoptimization of FMDV P1 region results in robust serotype-independent viral attenuation
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Medina, G.N., Diaz-San Segundo, F., Spinard III, E.J., Azzinaro, P.A., Rodriguez-Calzada, M., Gutkoska, J.R., Kloc, A., Rieder, A.E., Mueller, S., De Los Santos, T.B. 2023. Deoptimization of FMDV P1 region results in robust serotype-independent viral attenuation. Viruses. 15(6). https://doi.org/10.3390/v15061332.
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Mutation of FMDV Lpro H138 reside outside substrate binding domain drives viral attenuation in vitro and in swine
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Azzinaro, P.A., Medina, G.N., Rai, D., Ramirez Medina, E., Spinard Iii, E.J., Zhu, J.J., Rieder, A.E., De Los Santos, T.B., Diaz San Segundo, F.C. 2022. Mutation of FMDV Lpro H138 reside outside substrate binding domain drives viral attenuation in vitro and in swine. Frontiers in Veterinary Science. https://www.frontiersin.org/articles/10.3389/fvets.2022.1028077/full.
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Complete genome sequences of Foot-and-Mouth Disease Viruses of serotype O, EA-2 from cattle in Uganda during 2015-2016
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Ahmed, Z., Frank, M.N., Velazquez Salinas, L., Vanderwaal, K., Jia, W., Rieder, A.E. 2022. Complete genome sequences of Foot-and-Mouth Disease Viruses of serotype O, EA-2 from cattle in Uganda during 2015-2016. Microbiology Resource Announcements. https://doi.org/10.1128/mra.00445-22.
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Ecological and Anthropogenic Spatial Gradients Shape Patterns of Dispersal of Foot-and-Mouth Disease Virus
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Munsey, A., Mwiine, F., Ochwo, S., Velazquez Salinas, L., Ahmed, Z., Rodriguez, L.L., Rieder, A.E., Perez, A., Vanderwaall, K. 2022. Ecological and Anthropogenic Spatial Gradients Shape Patterns of Dispersal of Foot-and-Mouth Disease Virus. Viruses. https://doi.org/10.3390/pathogens11050524.
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Simultaneous and staggered footand-mouth disease virus coinfection of cattle
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Arzt, J., Bertram, M.R., Fish, I., Smoliga, G.R., Hartwig, E.J., Pauszek, S., Diaz San Segundo, F.C., Sitt, T., Rieder, A.E., Stenfeldt, C. 2021. Simultaneous and staggered footand-mouth disease virus coinfection of cattle. Journal of Virology. https://doi.org/10.1128/JVI.01650-21.
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Tracking the dispersal of foot-and-mouth disease virus serotype O in East Africa using phylodynamics
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Munsey, A., Mwiine, F., Ochwo, S., Velazquez Salinas, L., Ahmed, Z., Maree, F., Rodriguez, L.L., Rieder, A.E., Perez, A., Vanderwaall, K., Dellicour, S. 2021. Tracking the dispersal of foot-and-mouth disease virus serotype O in East Africa using phylodynamics. Molecular Ecology. https://doi.org/10.1111/mec.15991.
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Use of synonymous deoptimization for the development of modified live attenuated strains of foot and mouth disease virus
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Diaz San Segundo, F.C., Medina, G., Spinard, E., Kloc, A., Ramirez-Medina, E., Azzinaro, P.A., Mueller, S., Rieder, A.E., De Los Santos, T.B. 2021. Use of synonymous deoptimization for the development of modified live attenuated strains of foot and mouth disease virus. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2020.610286.
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Novel Foot-and-Mouth Disease vaccine platform:Formulations for safe and DIVA-compatible FMD vaccines with improved potency
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Hardham, J., Krug, P., Pacheco, J., Thompson, J., Domanowski, P., Gay, C.G., Rodriguez, L.L., Rieder, A.E. 2020. Novel Foot-and-Mouth disease vaccine platform: Formulations for safe and DIVA-compatible FMD vaccines with improved potency. Frontiers in Veterinary Science. https://doi.org/https://doi.org/10.3389/fvets.2020.554305.
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Diagnostic and epitope mapping potential of single-chain antibody fragments against foot-and-mouth disease serotype A, SAT1 and SAT3 viruses
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Chitray, M., Opperman, P., Rotherham, L., Fehrsen, J., Frischmuth, J., Rieder, A.E., Maree, F. 2020. Diagnostic and epitope mapping potential of single-chain antibody fragments against foot-and-mouth disease serotype A, SAT1 and SAT3 viruses. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2020.00475.
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Residues within the foot-and-mouth disease virus 3dpol nuclear localization signal affect polymerase fidelity
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Kloc, A., Rai, D.K., Kenney, M.A., Schafer, E.A., Rieder, A.E., Gladue, D. 2020. Residues within the foot-and-mouth disease virus 3dpol nuclear localization signal affect polymerase fidelity. Journal of Virology. https://doi.org/10.1128/JVI.00833-20.
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Genetic diversity of circulating foot and mouth 1 disease virus in Uganda cross-sectional study during 2014-2017
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Velazquez-Salinas, L., Mwiine, F.N., Ahmed, Z., Ochwo, S., Munsey, A., Lutwama, J.J., Vanderwaal, K., Perez, A., Rieder, A.E. 2020. Genetic diversity of circulating foot and mouth 1 disease virus in Uganda cross-sectional study during 2014-2017. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2020.00162.
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Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV A24 LL3B3D) Is Fully Attenuated in Pigs
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Eschbaumer, M., Dill, V., Carlson, J.C., Arzt, J., Stenfeldt, C., Krug, P., Hardham, J., Stegner, J.E., Rodriguez, L.L., Rieder, A.E. 2020. Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV A24 LL3B3D) Is Fully Attenuated in Pigs. Pathogens. https://doi.org/10.3390/pathogens9020129.
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Spatial distribution and risk factors for foot and mouth disease virus in Uganda: Opportunities for strategic surveillance
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Munsey, A., Mwiine, F., Ochwo, S., Velazquez-Salinas, L., Admed, Z., Maree, F.F., Rodriguez, L.L., Rieder, A.E., Perez, A., Vanderwaal, K. 2019. Spatial distribution and risk factors for foot and mouth disease virus in Uganda: Opportunities for strategic surveillance. Preventive Veterinary Medicine. https://doi.org/10.1016/j.prevetmed.2019.104766.
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Duration of protection and immunity induced by an adenovirus- vectored foot-and-mouth disease virus serotype A24 subunit vaccine in Holstein steers
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Duration of protection and humoral immunity induced by an adenovirus-vectored subunit vaccine for foot-and-mouth disease (FMD) in Holstein steers
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Sitt, T., Keeney, M., Barrera, J., Pandya, M., Eckstrom, K., Warner, M., Pacheco, J., Larocco, M., Palarea-Albaladejo, J., Brake, D., Rieder, A.E., Arzt, J., Barlow, J., Golde, W. 2019. Duration of protection and humoral immunity induced by an adenovirus-vectored subunit vaccine for foot-and-mouth disease (FMD) in Holstein steers. Meeting Abstract. https://doi.org/10.1016/j.vaccine.2019.08.017.
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Serological and phylogenetic characterization of foot and mouth disease viruses from Uganda during cross sectional surveillance study in cattle between 2014 and 2017
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Mwiine, F.N., Velazquez-Salinas, L., Ahmed, Z., Ochwo, S., Munsey, A., Kenney, M.A., Lutwama, J.J., Maree, F.F., Lobel, L., Perez, A.M., Rodriguez, L.L., Vanderwaal, K., Rieder, A.E. 2019. Serological and phylogenetic characterization of foot and mouth disease viruses from Uganda during cross sectional surveillance study in cattle between 2014 and 2017. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13249.
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The evolution of a super-swarm of foot-and-mouth disease virus in cattle
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Arzt, J., Fish, I., Pauszek, S.J., Johnson, S.L., Chain, P.S., Rai, D.K., Rieder, A.E., Goldberg, T.L., Rodriguez, L.L., Stenfeldt, C. 2019. The evolution of a super-swarm of foot-and-mouth disease virus in cattle. Virology. https://doi.org/10.1371/journal.pone.0210847.
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The development and validation of a novel nanobody-based competitive ELISA for the detection of foot and mouth disease 3ABC antibodies in cattle
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Gelkop, S., Sobarzo, A., Brangel, P., Vincke, C., Romao, E., Fedida-Metula, S., Strom, N., Ataliba, I., Mwiin, F.N., Ochwo, S., Velazquez-Salinas, L., McKendry, R.A., Muyldermans, S., Lutwama, J.J., Rieder, A.E., Yavelsky, V., Lobel, L. 2018. The development and validation of a novel nanobody-based competitive ELISA for the detection of foot and mouth disease 3ABC antibodies in cattle. Frontiers in Veterinary Science. https://doi.org/10.3389/fvets.2018.00250.
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The roles of picornavirus untranslated regions in infection and innate immunity
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Kloc, A., Rai, D.K., Rieder, A.E. 2018. The roles of picornavirus untranslated regions in infection and innate immunity. Frontiers in Microbiology. 20(9):485. https://doi.org/10.3389/fmicb.2018.00485.
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An improved, rapid competitive ELISA using a novel conserved 3B epitope for the detection of serum antibodies to foot-and-mouth disease virus
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Chung, C.J., Clavijo, A., Bounpheng, M., Uddowla, S., Sayed, A., Dancho, B., Olesen, I.C., Pacheco, J., Kamicker, B.J., Brake, D.A., Bandaranayaka-Mudiyanselage, C., Lee, S.S., Rai, D.K., Rieder, A.E. 2018. An improved, rapid competitive ELISA using a novel conserved 3B epitope for the detection of serum antibodies to foot-and-mouth disease virus. Journal of Veterinary Diagnostic Investigation. 30(5):699-707. https://doi.org/10.1177/1040638718779641.
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Foot-and-mouth disease virus 5’-terminal S fragment is required for replication and modulation of the innate immune response in host cells
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Kloc, A., Diaz-San Segundo, F., Schafer, E.A., Rai, D.K., Kenney, M.A., De Los Santos, T.B., Rieder, A.E. 2017. Foot-and-mouth disease virus 5’-terminal S fragment is required for replication and modulation of the innate immune response in host cells. Virology. 512:132-143.
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Enhanced sensitivity in detection of antiviral antibody responses using biotinylation of foot-and-mouth disease virus (FMDV) capsids
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Kenney, M.A., Waters, R.A., Rieder, A.E., Pega, J., Perez-Filguera, M., Golde, W.T. 2017. Enhanced sensitivity in detection of antiviral antibody responses using biotinylation of foot-and-mouth disease virus (FMDV) capsids. Journal of Immunological Methods. 450:1-9. https://doi.org/10.1016/j.jim.2017.07.001.
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Differential replication of foot-and-mouth disease viruses in mice determine lethality
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Cacciabue, M., Garcia-Nunez, M.S., Delgado, F., Curra, A., Marrero, R., Molinari, P., Rieder, A.E., Carrillo, E., Gismondi, M.I. 2017. Differential replication of foot-and-mouth disease viruses in mice determine lethality. Virology. 509:195-204. doi: 10.1016/j.virol.2017.06.012.
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Attenuation of foot-and-mouth disease virus by engineered viral polymerase fidelity
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Rai, D.K., Diaz-San Segundo, F., Campagnola, G., Schafer, E.A., Kloc, A., Keith, A., De Los Santos, T.B., Peersen, O., Rieder, A.E. 2017. Attenuation of foot-and-mouth disease virus by engineered viral polymerase fidelity. Journal of Virology. doi: 10.1128/JVI.00081-17.
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Insights into jumonji c-domain containing protein 6 (JMJD6): a multifactorial role in FMDV replication in cells
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Lawrence, P.J., Rieder, A.E. 2017. Insights into jumonji c-domain containing protein 6 (JMJD6): a multifactorial role in FMDV replication in cells. Virus Genes. 53(3):340-351.
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Interaction between FMDV Lpro and transcription factor ADNP is required for viral replication
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Medina, G.N., Knudsen, G.M., Greninger, A.L., Kloc, A., Diaz-San Segundo, F., Rieder, A.E., Grubman, M., Derisi, J.L., De Los Santos, T.B. 2017. Interaction between FMDV Lpro and transcription factor ADNP is required for viral replication. Virology. 505:12-22. doi: 10.1016/j.virol.2017.02.010.
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Foot-and-mouth disease virus receptors: multiple gateways to initiate infection
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Lawrence, P.J., Rieder, A.E. 2017. Foot-and-mouth disease virus receptors: multiple gateways to initiate infection. In: Sobrino, F. and Domingo, E. Foot-and-Mouth Disease Virus: Current Research and Emerging Trends. Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Madrid, Spain. Caister Academic Press. pp. 107-136.
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Novel 6xHis tagged foot-and-mouth disease virus vaccine bound to nanolipoprotein adjuvant via metal ions provides antigenic distinction and effective protective immunity
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Rai, D., Daiz-San Segundo, F., Schafer, E.A., Burrage, T., Rodriguez, L.L., De Los Santos, T.B., Hoeprich, P.D., Rieder, A.E. 2016. Novel 6xHis tagged Foot-and-Mouth Disease Virus vaccine bound to nanolipoprotein adjuvant via metal ions provides antigenic distinction and effective protective immunity. Virology. 495:136-147. doi: 10.1016/j.virol.2016.04.027.
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Role of Jumonji c-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus
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Lawrence, P.J., Rai, D.K., Conderino, J.S., Uddowla, S., Rieder, A.E. 2016. Role of Jumonji c-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus. Virology. 492:38-52. doi: 10.1016/j-virol.2016.02.005.
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Pathogenesis and micro-anatomic characterization of a cell-adapted mutant foot-and-mouth disease virus in cattle: impact of the Jumonji C-domain containing protein 6 (JMJD6) and route of innoculation
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Lawrence, P.J., Pacheco Tobin, J., Stenfeldt, C., Arzt, J., Rai, D., Rieder, A.E. 2016. Pathogenesis and micro-anatomic characterization of a cell-adapted mutant foot-and-mouth disease virus in cattle: impact of the Jumonji C-domain containing protein 6 (JMJD6) and route of innoculation. Journal of Virology. 492:108-117. doi: 10.1016/j.virol.2016.02.004.
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Bioinformatics and molecular analysis of the evolutionary relationship between bovine rhinitis A viruses and foot-and-mouth disease virus
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Rai, D., Lawrence, P.J., Pauszek, S.J., Piccone, M.E., Knowles, N., Rieder, A.E. 2016. Bioinformatics and molecular analysis of the evolutionary relationship between bovine rhinitis A viruses and foot-and-mouth disease virus. Bioinformatics and Biology Insights. 9:43-58. doi: 10.4137/BBI.S37223.
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Analysis of the interactions between host factor Sam68 and viral elements during foot-and-mouth disease virus infection
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Rai, D., Lawrence, P.J., Schafer, E.A., Kloc, A., Rieder, A.E. 2015. Analysis of the interactions between host factor Sam68 and viral elements during foot-and-mouth disease virus infection. Virology Journal. 12:224. https://doi.org/10.1186/s12985-015-0452-8.
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Cell culture adaptation mutations in foot-and-mouth disease virus serotype A capsid proteins: implications for receptor interactions
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Mohapatra, J.K., Pandey, L.K., Rai, D.K., Das, B., Rodriguez, L.L., Rout, M., Subramaniam, S., Sanyal, A., Rieder, A.E., Pattnaik, B. 2015. Cell culture adaptation mutations in foot-and-mouth disease virus serotype A capsid proteins: implications for receptor interactions. Journal of General Virology. 96:553-564.
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Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of jumonji C-domain containing protein 6 in RHA demethylation
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Lawrence, P., Conderino, J., Rieder, A.E. 2014. Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of jumonji C-domain containing protein 6 in RHA demethylation. Virology. 452-453:1-11.
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Enhanced IRES activity by the 3’UTR element determines the virulence of FMDV isolates
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Garcia-Nunez, S., Gismondi, M.I., Konig, G., Berinstein, A., Taboga, O., Rieder, A.E., Martinez-Salas, E., Carrillo, E. 2014. Enhanced IRES activity by the 3’UTR element determines the virulence of FMDV isolates. Virology. 448:303-313.
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Characterization of a chimeric foot-and-mouth disease virus bearing bovine rhinitis B virus leader proteinase
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Uddowla, S., Pacheco Tobin, J., Larson, C., Bishop, E.A., Rodriguez, L.L., Rai, D., Arzt, J., Rieder, A.E. 2013. Characterization of a chimeric foot-and-mouth disease virus bearing bovine rhinitis B virus leader proteinase. Virology. 447(1-2):172-180.
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Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of Foot-and-Mouth Disease Virus in host cells.
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Rai, D.K., Schafer, E.A., Singh, K., Mcintosh, M., Sarafianos, S., Rieder, A.E. 2013. Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of Foot-and-Mouth Disease Virus in host cells. Antiviral Research. 98(3):380-385 DOI:10.1016/j.antiviral.2013.03.022.
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Analysis of SAT type foot-and-mouth disease virus capsid proteins and the identification of putative amino acid residues in virus stability
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Maree, F.F., Blignaut, B., De Beer, T.A., Rieder, A.E. 2013. Analysis of SAT type foot-and-mouth disease virus capsid proteins and the identification of putative amino acid residues in virus stability. PLoS One. 8(5):e61612 DOI:10.1371/journal.pone.0061612.
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Structure-based discovery of foot-and-mouth disease inhibitors that target the 3Dpol RNA-dependent RNA polymerase
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Examination of soluble integrin resistant mutants of foot-and-mouth disease virus (FMDV)
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Lawrence, P., Larocco, M.A., Schafer, E.A., Baxt, B., Rieder, A.E. 2013. Examination of soluble integrin resistant mutants of foot-and-mouth disease virus (FMDV). Virology Journal. 10(1):2.
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Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis
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Lawrence, P., Uddowla, S., Pacheco Tobin, J., Kotecha, A., Fry, E., Rieder, A.E. 2012. Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis. Virology. 136(1):150-161.
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Theiler’s murine encephalomyelitis virus contrasts with encephalomyocarditis and foot-and-mouth disease viruses in its functional utilization of the StopGo non-standard translation mechanism
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Loughran, G., Libbey, J.E., Uddowla, S., Scallan, M.F., Ryan, M.D., Fujinami, R.S., Rieder, A.E., Atkins, J.F. 2013. Theiler’s murine encephalomyelitis virus contrasts with encephalomyocarditis and foot-and-mouth disease viruses in its functional utilization of the StopGo non-standard translation mechanism. Journal of General Virology. 94(2):348-353.
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A safe foot-and-mouth disease vaccine platform with two negative markers for differentiating infected from vaccinated animals (DIVA)
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Uddowla, S., Hollister, J., Pacheco Tobin, J., Rodriguez, L.L., Rieder, A.E. 2012. A safe foot-and-mouth disease vaccine platform with two negative markers for differentiating infected from vaccinated animals (DIVA). Journal of Virology. Nov,86(21):11675-11685.
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Homology modelling and analysis of structure predictions of the bovine rhinitis B virus RNA-dependent RNA polymerase (RdRp)
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Rai, D., Rieder, A.E. 2012. Homology modelling and analysis of structure predictions of the bovine rhinitis B virus RNA-dependent RNA polymerase (RdRp). International Journal of Molecular Sciences. 2012(3):8998-9013.
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Host and viral factors responsible for FMD pathogenesis
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Lawrence, P., Rieder, A.E. 2013. Host and viral factors responsible for FMD pathogenesis. In: Topics in Foot and Mouth Disease. Scientific Developments and Technical Challenges in the Progresive Control of Foot-and-Mouth Diseasein South Asia, February 13-15, 2012, New Delhi, India. p. 8-23.
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The nuclear protein Sam68 is cleaved by the FMDV 3C protease redistributing Sam68 to the cytoplasm during FMDV infection of host cells
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Lawrence, P.J., Schafer, E.A., Rieder, A.E. 2012. The nuclear protein Sam68 is cleaved by the FMDV 3C protease redistributing Sam68 to the cytoplasm during FMDV infection of host cells. Virology. 425:40-52.
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Predicting antigenic sites on the foot-and-mouth disease virus capsid of the South African Territories (SAT) types using virus neutralization data
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Maree, F.F., Blignaut, B., Esterhuysen, J.J., De Beer, T., Theron, J., O'Neill, H.G., Rieder, A.E. 2011. Predicting antigenic sites on the foot-and-mouth disease virus capsid of the South African Territories (SAT) types using virus neutralization data. Journal of General Virology. 92(10):2297-2309.
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The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions
- (Review Article)
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Arzt, J., Baxt, B., Grubman, M.J., Jackson, T., Juleff, N., Rhyan, J., Rieder, A.E., Waters, R., Rodriguez, L.L. 2011. The pathogenesis of foot-and-mouth disease II; viral pathways in swine, small ruminants, and wildlife, myotropism, chronic syndromes, and molecular virus-host interactions. Transboundary and Emerging Diseases. 58(4):305-326.
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Custom-engineered chimeric foot-and-mouth disease vaccine elicits protective immune responses in pigs
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Blignaut, B., Visser, N., Theron, J., Rieder, A.E., Maree, F.F. 2011. Custom-engineered chimeric foot-and-mouth disease vaccine elicits protective immune responses in pigs. Journal of General Virology. 92(4):849-859.
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Analysis of sat type foot-and-mouth disease virus capsid proteins: influence of receptor usage on the properties of virus particles
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Maree, F.F., Blignaut, B., Aschenbrenner, L., Burrage, T., Rieder, A.E. 2010. Analysis of sat type foot-and-mouth disease virus capsid proteins: influence of receptor usage on the properties of virus particles. Virus Research. 155:462-472.
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Sequence-based prediction for vaccine strain selection and identification of antigenic variability in foot-and-mouth disease virus
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Reeve, R., Blignaut, B., Esterhuysen, J.J., Opperman, P., Matthews, L., Fry, E., De Beer, T.A., Theron, J., Rieder, A.E., Vosloo, W., O'Neill, H.G., Haydon, D.T., Maree, F.F. 2010. Sequence-based prediction for vaccine strain selection and identification of antigenic variability in foot-and-mouth disease virus. PLoS Computational Biology. DOI: 10.1371/journal.pcbi.1001027.
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Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase
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Durk, R.C., Singh, K., Cornelison, C.A., Rai, D.K., Matzek, K.B., Leslie, M.D., Schafer, E.A., Marchand, B., Adedeji, A., Michailidis, E., Dorst, C.A., Moran, J., Pautler, C., Rodriguez, L.L., Mcintosh, M.A., Rieder, A.E., Sarafianos, S.G. 2010. Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase. PLoS One. DOI: 10.1371/journal.pone.0015049.
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Mapping of amino acid residues responsible for adhesion of cell culture-adapted foot-and-mouth disease SAT type viruses
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Maree, F.F., Blignaut, B., De Beer, T.A., Visser, N., Rieder, A.E. 2011. Mapping of amino acid residues responsible for adhesion of cell culture-adapted foot-and-mouth disease SAT type viruses. Virus Research. 153(1):82-91.
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Domain disruptions of individual 3B proteins for foot-and-mouth disease virus do not alter growth in cell culture nor virulence in cattle
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Pacheco Tobin, J., Piccone, M.E., Rieder, A.E., Pauszek, S.J., Borca, M.V., Rodriguez, L.L. 2010. Domain disruptions of individual 3B proteins for foot-and-mouth disease virus do not alter growth in cell culture nor virulence in cattle. Virology. DOI: 10.1016/j.virol.2010.05.036.
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The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle
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Piccone, M.E., Pacheco Tobin, J., Pauszek, S.J., Borca, M.V., Rieder, A.E., Kramer Jr, E.V., Zhu, J.J., Rodriguez, L.L. 2010. The region between the two polyprotein initiation codons of foot-and-mouth disease virus is critical for virulence in cattle. Virology. 396:152-159.
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Identification of RNA Helicase A (RHA) as a New Host Factor in the Replication Cycle of FMDV
- (Peer Reviewed Journal)
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Lawrence, P.J., Rieder, A.E. 2009 Identification of RNA Helicase A (RHA) as a New Host Factor in the Replication Cycle of FMDV. Journal of Virology. 83 (21): 11356-11366.
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Studies on Sam68 a cell factor involved in the life cycle of foot-and-mouth disease virus
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Lawrence, P.J., Rieder, A.E. 2009. Studies on Sam68 a cell factor involved in the life cycle of foot-and-mouth disease virus. American Society for Virology Meeting. Paper No. W36-8: p. 177.
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Sequence analysis of a bovine rhinovirus type 1 strain RS3x
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Piccone, M.E., Kramer Jr, E.V., Knowles, N.J., Rieder, A.E. 2009. Sequence analysis of a bovine rhinovirus type 1 strain RS3x. American Society for Virology Meeting. Paper No. 32-8: P. 337.
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Host Cell Factors Involved in the Life Cycle of FMDV
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Lawrence, P., Rieder, A.E. 2008. Host Cell Factors Involved in the Life Cycle of FMDV. European Study Group on the Molecular Biology of Picornaviruses. P 85
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Role of the Region Located Between the Two AUG Initiation Codons in the Pathogenesis of Foot-and-Mouth Disease Virus (FMDV)
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Piccone, M.E., Pacheco Tobin, J., Pauszek, S.J., Borca, M.V., Rieder, A.E., Rodriguez, L.L. 2008. Role of the Region Located Between the Two AUG Initiation Codons in the Pathogenesis of Foot-and-Mouth Disease Virus (FMDV). European Study Group on the Molecular Biology of Picornaviruses. p. 199.
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A Reverse Genetic System Provides a Powerful Tool in the Design of Foot-and-Mouth Disease Viruses with Enhanced Properties
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Maree, F.F., Blignaut, B., Theron, J., Visser, N., Rieder, A.E. 2008. A reverse genetic system provides a powerful tool in the design of foot-and-mouth disease viruses with enhanced properties. European Study Group on the Molecular Biology of Picornaviruses.P 202
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SAT Type Foot-and-Mouth Disease (FMD) Chimeric Vaccine Elicits Protection in Pigs
- (Abstract Only)
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Blignault, B., Theron, J., Visser, N., Rieder, A.E., Maree, F. 2008. Sat type foot-and-mouth disease (fmd) chimeric vaccine elicits protection in pigs. European Study Group on the Molecular Biology of Picornaviruses. p. 133.
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Mapping of Antigenic Sites on a SAT2 Foot-and-Mouth Disease Virus Vaccine Strain
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Opperman, P.A., Maree, F.F., Blignaut, B., Vosloo, W., Rieder, A.E., Theron, J.J. 2008. Mapping of Antigenic Sites on a SAT2 Foot-and-Mouth Disease Virus Vaccine Strain. European Study Group on the Molecular Biology of Picornaviruses. P 204
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Chimeric Foot-and-Mouth Disease Viruses: Evaluation of Their Efficacy as Potential Marker Vaccines in Cattle
- (Peer Reviewed Journal)
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Fowler, V.L., Paton, D.J., Rieder, A.E., Barnett, P.V. 2008. Chimeric Foot-and-Mouth Disease Viruses: Evaluation of Their Efficacy as Potential Marker Vaccines in Cattle. Vaccine. 26:1982-1989.
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Molecular Characterization of a Foot-and-Mouth Disease Virus (FMDV) Containing a 57-Nucleotide Insertion in the 3' Untranslated Region (3'UTR)
- (Peer Reviewed Journal)
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Piccone, M.E., Pauszek, S.J., Pacheco Tobin, J., Rieder, A.E., Kramer, E., Rodriguez, L.L. 2009. Molecular Characterization of a Foot-and-Mouth Disease Virus (FMDV) Containing a 57-Nucleotide Insertion in the 3' Untranslated Region (3'UTR). Archives of Virology. 154:671-676.
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PATHOGENIC CHARACTERISTICS OF THE KOREAN 2002 ISOLATE OF FOOT-AND-MOUTH DISEASE VIRUS SEROTYPE O IN PIGS AND CATTLE
- (Peer Reviewed Journal)
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Oem, J., Yeh, M., Mckenna, T., Hayes, J.R., Rieder, A.E., Giuffre, A.C., Robida, J.M., Lee, K., Cho, I., Fang, X., Joo, Y., Park, J. 2008. Pathogenic Characteristics of the Korean 2002 Isolate of Foot-and-Mouth Disease Virus Serotype O in Pigs and Cattle. Journal of Comparative Pathology. 138(4):204-214.
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Molecular and Phylogenetic Analyses of Bovine Rhinovirus Type 2 Shows it is Closely Related to Foot-and-Mouth Disease Virus
- (Peer Reviewed Journal)
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Hollister, J.R., Vagnozzi, A., Knowles, N., Rieder, A.E. 2008. Molecular and Phylogenetic Analyses of Bovine Rhinovirus Type 2 Shows it is Closely Related to Foot-and-Mouth Disease Virus. Virology. Vol 373/2: 411-425.
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Picornaviridae
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Rieder, A.E. 2007. Picornaviridae. Book Chapter. 2007. P523-545.
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Inhibition of Foot-and-Mouth Disease Virus in Cell Culture with Antisense Morpholino Oligomers
- (Peer Reviewed Journal)
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Vagnozzi, A., Stein, D.A., Iversen, P.L., Rieder, A.E. 2007. Inhibition of Foot-and-Mouth Disease Virus in Cell Culture with Antisense Morpholino Oligomers. Journal of Virology. 81:11669-11680.
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MOLECULAR ANALYSIS OF BOVINE RHINOVIRUS TYPE 2 SHOWS A CLOSE RELATIONSHIP TO THE APHTHOVIRUSES
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Hollister, J.R., Vagnozzi, A., Knowles, N.J., Rieder, A.E. 2006. Molecular Analysis of Bovine Rhinovirus Type 2 Shows a Close Relationship to the Aphthoviruses. European Study Group on the Molecular Biology of Picornaviruses (EUROPIC) 2006 Meeting, page A5.
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Growth Determination for Genetic Engineered SAT Type Foot-and-Mouth Disease Viruses
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Blignaut, B., Maree, F., Theron, J., Rieder, A.E., Vosloo, W. 2006. Growth Determination for Genetic Engineered SAT Type Foot-and-Mouth Disease Viruses.European Study Group on the Molecular Biology of Picornaviruses (EUROPIC) 2006 Meeting, page B10.
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Selection of Variants Utilizing Heparin Sulphate For Cell Entry When South African Territories Foot-and-Mouth Disease Virus is Adapted for Growth on Cell Culture
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Maree, F.F., Blignaut, B., Van Heerden, J., Vosloo, W., Theron, J., Rieder, A.E. 2006. Selection of Variants Utilizing Heparin Sulphate For Cell Entry When South African Territories Foot-and-Mouth Disease Virus is Adapted for Growth on Cell Culture. European Study Group on the Molecular Biology of Picornaviruses (EUROPIC) 2006 Meeting, page F14.
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IN VITRO SELECTION AND ANALYSIS OF FOOT-AND-MOUTH DISEASE VIRUS RECEPTOR NEUTRALIZATION ESCAPE MUTANTS
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Rieder, A.E., Larocco, M.A., Baxt, B. 2006. In vitro selection and analysis of foot-and-mouth disease virus receptor neutralization escape mutants. American Society for Virology Annual Meeting. 2006. P 209.
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ANALYSIS OF THE RECEPTOR USAGE AND GROWTH DETERMINANTS OF OUTBREAK AND VACCINE STRAINS OF SOUTH AFRICAN TERRITORIES OF FOOT-AND-MOUTH DISEASE VIRUS
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Maree, F.F., Aschenbrenner, L.M., Baxt, B., Rieder, A.E. 2006. Analysis of the receptor usage and growth determinants of outbreak and vaccine strains of south african territories of foot-and-mouth disease virus. Keystone Symposia. 2006. P. 74.
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ANALYSIS OF FOOT-AND-MOUTH DISEASE VIRUS TYPE A24 ISOLATE CONTAINING AN SGD RECEPTOR RECOGNITION SITE IN VITRO AND ITS PATHOGENESIS IN CATTLE
- (Peer Reviewed Journal)
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Henry, T.M., Duque, H., Baxt, B., Rieder, A.E. 2005. Analysis of Foot-and-Mouth Disease Virus Type A24 Isolate Containing an SGD Receptor Recognition Site In Vitro and Its Pathogenesis in Cattle. Journal of Virology. Vol 79:20, p. 12989-12998.
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DEVELOPMENT OF A MAMMALIAN CELL-FREE SYSTEM TO INVESTIGATE REPLICATION OF F00T-AND-MOUTH DISEASE AND THE ROLE OF HOST FACTORS IN VIRUS SYNTHESIS
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Rieder, A.E. 2005. Development of a Mammalian Cell-free System to Investigate Replication of Foot-and-Mouth Disease and the Role of Host Factors in Virus Synthesis. XIIIth Meeting of the European Study Group for the Molecular Biology of Picornaviruses. P.H24
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RECOMBINANT ENGINEERED SAT1 FOOT-AND-MOUTH DISEASE VIRUS AS AN APPROACH TO INVESTIGATE RECEPTOR USAGE AND GROWTH DETERMINANTS OF OUTBREAK STRAINS
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Maree, F.F., Rieder, A.E. 2005. Recombinant Engineered sat1 Foot-and-Mouth Disease Virus as an Approach to Investigate Receptor Usage and Growth Determinants of Outbreak Strains. XIIIth Meeting of the European Study Group for the Molecular Biology of Picornaviruses. p 123.
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NOVEL TOOLS TO PREVENT AND ERADICATE FOREIGN ANIMAL DISEASES
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Rodriguez, L.L., Baxt, B., Rieder, A.E., Golde, W.T., Borca, M.V., Grubman, M.J. 2005. Novel tools to prevent and eradicate foreign animal diseases. American Society for Microbiology Biodefense Meeting. p 41.
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PHENOTYPIC AND GENETIC CHANGES IN COXSACKIEVIRUS B5 FOLLOWING REPEATED PASSAGING IN MOUSE PANCREAS IN VIVO
- (Peer Reviewed Journal)
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Haider, A., Davydova, B., Smura, T., Kaialainen, S., Ylipaasto, P., Saario, E., Hovi, T., Rieder, A.E., Roivainen, M. 2005. Phenotypic and genetic changes in coxsackievirus b5 following repeated passaging in mouse pancreas in vivo. Journal of Medical Virology. 75 (4), 566-574
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MOLECULAR ASPECTS OF FOOT-AND-MOUTH DISEASE VIRUS VIRULENCE AND HOST RANGE: ROLE OF HOST CELL RECEPTORS AND VIRAL FACTORS
- (Review Article)
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Baxt, B., Rieder, A.E. 2004. Molecular Aspects of Foot-and-Mouth Disease Virus Virulence and Host Range: Role of Host Cell Receptors and Viral Factors. Foot-and-Mouth Disease: Current Perspectives. 145-172.
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ARS News Articles
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