Submitted to: Book Chapter
Publication Type: Book / chapter
Publication Acceptance Date: 12/18/2002
Publication Date: 12/1/2003
Citation: BOOTH, S.L. DIETARY VITAMIN K AND SKELETAL HEALTH. NEW SA, BONJOUR J-P, EDS. NUTRITIONAL ASPECTS OF BONE HEALTH, CAMBRIDGE, UK: THE ROYAL SOCIETY OF CHEMISTRY, 2003:323-34. Interpretive Summary:
Technical Abstract: Average self-reported dietary intakes of vitamin K are below recommended intakes among adults in the U.S. and U.K.. Low dietary intakes of vitamin K are potentially a modifiable risk factor for osteoporosis. In humans, much of the supporting evidence of a role for dietary vitamin K in age-related bone loss is based on reported associations between dietary intakes or biological markers of vitamin K status and bone mineral density (BMD) or hip fracture risk. However, one criticism of these epidemiologic data is the potential confounding effect of overall poor nutrition. There is also some evidence that different forms of vitamin K may have variable influence on bone turnover. The proposed dietary role of vitamin K as a risk factor for osteoporosis would be strengthened if controlled changes in vitamin K intakes, obtained from the diet or supplements, were consistently shown to influence bone metabolism.