|SHAH, DEVENDRAH - Washington State University|
|PAUL, NARAYAN - Texas A&M University|
|SISCHO, WILLIAM - Washington State University|
|CRESPO, ROCIO - Washington State University|
Submitted to: Poultry Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/16/2016
Publication Date: 3/1/2017
Citation: Shah, D.H., Paul, N.C., Sischo, W.C., Crespo, R., Guard, J.Y. 2017. Population dynamics and antimicrobial resistance of the most prevalent poultry-associated Salmonella serotypes. Poultry Science, Volume 96 (3),687-702.
Interpretive Summary: Salmonella spp. is the most predominant bacterial cause of foodborne gastroenteritis in humans. Due to the risk of human infection associated with poultry products and the prevalence of antimicrobial resistance, Salmonella also poses a significant challenge to commercial poultry production. During the last decade (2002 to 2012), the 12 most prevalent poultry-associated Salmonella serotypes (MPPSTs) were frequently and consistently isolated from poultry products in the United States. These MPPSTs and their percent prevalence in poultry products include Kentucky (4%), Enteritidis (2%) Heidelberg (2%), Typhimurium (2%), S. I 4,,12:i:- (0.31%), Montevideo (0.20%), Infantis (0.16%) Schwarzengrund (0.15%), Hadar (0.15%), Mbandaka (0.13%), Thompson (0.12%), and Senftenberg (0.04%). All MPPSTs except Kentucky are among the top 30 clinically significant serotypes that cause human illnesses in the United States. However, with the exception of a few widely studied serotypes such as S. Enteritidis and Typhimurium, the ecology and epidemiology of the majority of MPPSTs is still remain poorly investigated. Published data from the United States suggests that MPPSTs such as Heidelberg, Typhimurium, Kentucky, and Senftenberg are more likely to be multi-drug resistant (MDR, =3 antimicrobial classes) whereas Enteritidis, Montevideo, Schwarzengrund, Hadar, Infantis, Thompson, and Mbandaka are generally pan-susceptible or display resistance to fewer antimicrobials. In contrast, the majority of MPPSTs isolated globally have been reported to display MDR phenotype. There also appears to be an international spread of a few MDR serotypes including Kentucky, Schwarzengrund, Hadar, Thomson, Senftenberg, and Enteritidis, which may pose significant challenges to the public health. The current knowledge gaps on the ecology, epidemiology, and antimicrobial resistance of MPPSTs are discussed.
Technical Abstract: Salmonella enterica is an important food borne pathogen but only about 30 serotypes out of over 1500 within subspecies 1 are a persistent problem. Some of these 30 serotypes harbor more antibiotic resistances than others, and this review investigates what is known about the ecology, epidemiology and resistance patterns of the most-prevalent poultry-associated Salmonella serotypes (MPPSTs). The focus is on poultry because it is a food source that is a frequent vehicle for food borne illness.