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ARS Home » Northeast Area » Wyndmoor, Pennsylvania » Eastern Regional Research Center » Molecular Characterization of Foodborne Pathogens Research » Research » Publications at this Location » Publication #320186

Research Project: GENOMIC AND PROTEOMIC ANALYSIS OF FOODBORNE PATHOGENS

Location: Molecular Characterization of Foodborne Pathogens Research

Title: Whole-genome sequence of Escherichia coli serotype O157:H7 strain EDL932 (ATCC 43894)

Author
item Uhlich, Gaylen
item Paoli, George
item Chen, Chin-yi
item Cottrell, Bryan
item Zhang, Xinmin - University Of Wisconsin
item Yan, Xianghe

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/25/2016
Publication Date: 7/14/2016
Citation: Uhlich, G.A., Paoli, G., Chen, C., Cottrell, B.J., Zhang, X., Yan, X. 2016. Whole-genome sequence of Escherichia coli serotype O157:H7 strain EDL932 (ATCC 43894). Genome Announcements. doi: 10.1128/genomeA.00647-16.

Interpretive Summary: Escherichia coli serotype O157:H7 EDL 933 is a ground beef isolate associated with a 1983 hemorrhagic colitis outbreak. It is considered the prototype O157:H7 strain and its derived genome sequence is a standard reference strain that is used for comparative genomic studies of other Shiga toxin-producing E. coli (STEC). However, a serotype O157:H7 strain was also isolated from a patient stool sample associated with that outbreak and it has been assumed to be quite similar or identical to the ground beef isolate. Here we report the genome sequence of the patient-associated counterpart of that outbreak, stool isolate EDL 932.

Technical Abstract: Escherichia coli serotype O157:H7 EDL 933 is a ground beef isolate associated with a 1983 hemorrhagic colitis outbreak. Considered the prototype O157:H7 strain, its derived genome sequence is a standard reference strain for comparative genomic studies of Shiga toxin-producing E. coli (STEC). Here we report the genome sequence of the patient-associated counterpart of that outbreak, stool isolate EDL 932.