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ARS Home » Northeast Area » Wyndmoor, Pennsylvania » Eastern Regional Research Center » Molecular Characterization of Foodborne Pathogens Research » Research » Publications at this Location » Publication #312788

Title: Complete genome sequence of Campylobacter jejuni YH001 from beef liver which contains a novel plasmid

item He, Yiping
item Yan, Xianghe
item Reed, Sue
item Xie, Yanping
item Chen, Chinyi
item Irwin, Peter

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/29/2014
Publication Date: 2/5/2015
Citation: He, Y., Yan, X., Reed, S.A., Xie, Y., Chen, C., Irwin, P.L. 2015. Complete genome sequence of Campylobacter jejuni YH001 from beef liver which contains a novel plasmid. Genome Announcements. 3(1):e01492-14.

Interpretive Summary: Campylobacter is a widespread foodborne pathogen frequently found in poultry and other meat products and is the third most common cause of bacterial foodborne illness in the United States. In this work, the genome sequence of a specific Campylobacter jejuni strain recovered from retail beef liver was determined. Analysis of the DNA sequence showed many differences in this strain compared to the genomes of other Campylobacter strains that have been sequenced, indicating frequent genetic exchange in bacterial evolution. This work contributes to the knowledge of the genetic variability of Campylobacter strains, enhances the understanding how the organism causes disease and acquires resistance to antibiotics, and provides information that can be used to detect and control this pathogen.

Technical Abstract: Campylobacter jejuni is an important foodborne pathogen that causes gastroenteritis in humans and is commonly found in poultry and meat products. Here, we report the complete genome sequence of a Campylobacter jejuni strain recently isolated from retail beef liver. The genome size was 1,712,361 bp, with a 30.5% G+C content. The purpose of this work was to provide a fully annotated, whole-genome sequence for gaining insight into the potential virulence of this Campylobacter strain, and host adaptation and evolution in comparison to a collection of Campylobacter strains isolated from diverse sources.