Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 4/11/2013
Publication Date: 4/11/2013
Citation: Evans, K.O., Compton, D.L., Laszlo, J.A., Appell, M.D. 2013. Antioxidant behavior of 1-feruloyl-sn-glycerol and 1,3-diferuloyl-sn-glycerol in phospholipid liposomes 1 [abstract]. American Chemical Society. AGFD14.
Technical Abstract: 1-Feruloyl-sn-glycerol (FG) and 1,3-diferuloyl-sn-glycerol (DFG) are two natural plant compounds that may be useful in cosmeceutical, food, and skin care applications because of excellent antioxidant properties. FG and DFG enzymatically synthesized through esterification of glycerol and soybean oil mono- and diacylglycerols have proven to have similarly excellent antioxidant properties. The current work explored partitioning behavior, bilayer depth, and antioxidant behavior of ferulic acid (FA), FG, and DFG within 1,2-dioleoyl phosphatidylcholine liposomes. Data showed that the order of partitioning was DFG>>FG>FA. Bilayer depth measurement found all to reside nearly 13 Å from the center of the bilayer. Antioxidant measurements demonstrated that each had quite similar antioxidant behavior at 1-mole%, but clearly different capacity at 5-mole% (FA>FG>DFG).