Eric Cassmann
Virus and Prion Research
Research Veterinary Medical Officer
Phone: (515) 337-7190
Fax:
P.O. Box 70
1920 DAYTON AVE
AMES,
IA
50010
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
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will take you to the publication reprint.)
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Model systems to study Shiga toxin-producing Escherichia coli interactions with the bovine gastrointestinal tract
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White-Tailed Deer are Susceptible to the Agent of Sheep Scrapie after Experimental Oronasal Exposure
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The effect on prion incubation period after inoculation with dilutions within the dynamic range of ELISA absorbance
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Combinatorial treatment of brain samples from sheep with scrapie using sodium percarbonate, sodium dodecyl sulfate, and proteinase K increases survival time in inoculated susceptible sheep
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Harm, T.A., Smith, J.D., Cassmann, E.D., Greenlee, J.J. 2022. Combinatorial treatment of brain samples from sheep with scrapie using sodium percarbonate, sodium dodecyl sulfate, and proteinase K increases survival time in inoculated susceptible sheep. Research in Veterinary Science. 152:497-503. https://doi.org/10.1016/j.rvsc.2022.09.002.
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SARS-CoV-2: Experimental studies on deer-to-deer transmission
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Comparison of protein hallmarks of ferroptosis in mice with prion disease
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Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer
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Cassmann, E.D., Frese, A.J., Moore, S.J., Greenlee, J.J. 2022. Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer. Viruses. 14(7). Article 1578. https://doi.org/10.3390/v14071578.
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Exploring the possibility of CWD transmission through artificial insemination of semen from CWD positive bucks
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Cassmann, E.D., Greenlee, J.J. 2022. Exploring the possibility of CWD transmission through artificial insemination of semen from CWD positive bucks. North American Deer Farmer. p. 107-109.
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Cattle with the EK211 PRNP polymorphism are susceptible to the H-type bovine spongiform encephalopathy agent from either E211K or wild type donors after oronasal inoculation
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Greenlee, J.J., Cassmann, E.D., Moore, S., West Greenlee, H.M. 2022. Cattle with the EK211 PRNP polymorphism are susceptible to the H-type bovine spongiform encephalopathy agent from either E211K or wild type donors after oronasal inoculation. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):150. https://doi.org/10.1080/19336896.2022.2091286.
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The chronic wasting disease agent from white-tailed deer is highly infectious to humanized mice after passage through raccoons
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Cassmann, E.D., Qi, X., Kong, Q., Greenlee, J.J. 2022. The chronic wasting disease agent from white-tailed deer is highly infectious to humanized mice after passage through raccoons. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):120. https://doi.org/10.1080/19336896.2022.2091286.
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The chronic wasting disease agent from white-tailed deer fails to adapt to sheep upon second passage
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Frese, A.J., Cassmann, E.D., West Greenlee, H.M., Greenlee, J.J. 2022. The chronic wasting disease agent from white-tailed deer fails to adapt to sheep upon second passage. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):144. https://doi.org/10.1080/19336896.2022.2091286.
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Second passage of scrapie in white-tailed deer is discernable from chronic wasting disease
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Lambert, Z., West Greenlee, H.M., Cassmann, E.D., Greenlee, J.J. 2022. Second passage of scrapie in white-tailed deer is discernable from chronic wasting disease. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):181. https://doi.org/10.1080/19336896.2022.2091286.
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From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer
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Martins, M., Boggiatto, P.M., Buckley, A., Cassmann, E.D., Falkenberg, S.M., Caserta, L.C., Fernandes, M.H., Kanipe, C.R., Lager, K.M., Palmer, M.V., Diel, D.G. 2022. From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in highly susceptible white-tailed deer. PLoS Pathogens. 18(3). Article e1010197. https://doi.org/10.1371/journal.ppat.1010197.
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Chronic wasting disease isolates from Norway and North America lack evidence of common strain characteristics
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Cassmann, E.D., Greenlee, J.J. 2022. Chronic wasting disease isolates from Norway and North America lack evidence of common strain characteristics. North American Deer Farmer. p. 112.
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Differential accumulation of misfolded prion strains in natural hosts of prion diseases
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Lambert, Z., Greenlee, J.J., Cassmann, E.D., West Greenlee, H.M. 2021. Differential accumulation of misfolded prion strains in natural hosts of prion diseases. Viruses. 13(12). Article 2453. https://doi.org/10.3390/v13122453.
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Why are specific tissue samples required for detection of chronic wasting disease prions
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Harm, T., Cassmann, E.D., Greenlee, J.J. 2021. Why are specific tissue samples required for detection of chronic wasting disease prions. North American Deer Farmer. p. 40-43.
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Attempted transmission of the CWD agent to deer with potentially resistant prion protein genotypes
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Greenlee, J.J., Cassmann, E.D. 2022. Attempted transmission of the CWD agent to deer with potentially resistant prion protein genotypes. North American Deer Farmer. p. 117.
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Experimental oronasal transmission of chronic wasting disease agent from white-tailed deer to Suffolk sheep
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Cassmann, E.D., Moore, S., Greenlee, J.J. 2021. Experimental oronasal transmission of chronic wasting disease agent from white-tailed deer to Suffolk sheep. Emerging Infectious Diseases. 27(12). https://doi.org/10.3201/eid2712.204978.
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Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2
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Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Virtual. 86th North American Wildlife and Natural Resources Conference.
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Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2
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Palmer, M.V., Martins, M., Falkenberg, S.M., Buckley, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Journal of Virology. 95(11). Article e0008321. https://doi.org/10.1128/JVI.00083-21.
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Transmission of the atypical/nor98 scrapie agent to suffolk sheep with VRQ/ARQ, ARQ/ARQ, and ARQ/ARR genotypes
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Cassmann, E.D., Mammadova, J., Benestad, S., Moore, S., Greenlee, J.J. 2021. Transmission of the atypical/nor98 scrapie agent to suffolk sheep with VRQ/ARQ, ARQ/ARQ, and ARQ/ARR genotypes. PLoS ONE. 16(2). Article e0246503. https://doi.org/10.1371/journal.pone.0246503.
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Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2
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Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2020. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Virtual Symposium. December 1-3, 2020.
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Second passage of chronic wasting disease of mule deer in sheep compared to classical scrapie after intracranial inoculation
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Cassmann, E.D., Frese, R., Greenlee, J.J. 2021. Second passage of chronic wasting disease of mule deer in sheep compared to classical scrapie after intracranial inoculation. Journal of Veterinary Diagnostic Investigation. 33(4):711-720. https://doi.org/10.1177/10406387211017615.
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Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency
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Cassmann, E.D., Mammadova, N., Greenlee, J.J. 2020. Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency. PLoS ONE. 15(12). Article e0243009. https://doi.org/10.1371/journal.pone.0243009.
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Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ
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Cassmann, E.D., Moore, Sara, J, S.J., Kokemullar, R.D., Balkema-Buschman, A., Groschup, M., Nicholson, E.M., Greenlee, J.J. 2020. Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ. BMC Veterinary Research. 16. Article 383. https://doi.org/10.1186/s12917-020-02611-0.
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CWD research update from NADC
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Cassmann, E.D., Greenlee, J.J. 2020. CWD research update from NADC. North American Deer Farmer. p.72-73.
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ARS News Articles
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