Karley K Mahalak
Dairy and Functional Foods Research
Research Molecular Biologist
Phone: (215) 836-6922
Fax:
USDA,REE,ARS,NAA,ERRC
600 E MERMAID LANE
WYNDMOOR,
PA
190388598
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
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Lacticaseibacillus rhamnosus strain GG (LGG) regulate gut microbial metabolites, an in vitro study using three mature human gut microbial cultures in a simulator of human intestinal microbial ecosystem (SHIME)
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Liu, L.S., Narrowe, A.B., Firrman, J., Mahalak, K.K., Bobokalonov, J., Scarino Lemons, J.M., Bittinger, K., Daniel, S., Tanes, C., Mattei, L., Friendman, E., Soares, J.W., Masuko, K., Zeng, W., Tomasula, M.M. 2023. Lacticaseibacillus rhamnosus strain GG (LGG) regulate gut microbial metabolites, an in vitro study using three mature human gut microbial cultures in a simulator of human intestinal microbial ecosystem (SHIME). Foods. https://doi.org/10.3390/foods12112105.
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Fructooligosaccharides (FOS) differentially modifies the in vitro gut microbiota in an age-dependent manner.
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Mahalak, K.K., Firrman, J., Narrowe, A.B., Hu, W., Bittinger, K., Moustafa, A., Liu, L.S. 2023. Fructooligosaccharides (FOS) differentially modifies the in vitro gut microbiota in an age-dependent manner. Frontiers in Nutrition. https://doi.org/10.3389/fnut.2022.1058910.
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Persistence of the probiotic Lacticaseibacillus rhamnosus strain GG (LGG) in an in vitro model of the gut microbiome
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Mahalak, K.K., Firrman, J., Bobokalonov, J., Narrowe, A.B., Bittinger, K., Daniel, S., Tanes, C., Mattei, L., Zeng, W., Soares, J.W., Kobori, M., Scarino Lemons, J.M., Tomasula, M.M., Liu, L.S. 2022. Persistence of the probiotic Lacticaseibacillus rhamnosus strain GG (LGG) in an in vitro model of the gut microbiome. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms232112973.
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Changes to environmental pH alters the colon microbial community in terms of both structure and function: An in vitro analysis
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Firrman, J., Liu, L.S., Mahalak, K.K., Tu, V., Tanes, C., Bittinger, K., Bobokalonov, J., Mattei, L., Zhang, H., Van Den Abeele, P. 2022. Changes to environmental pH alters the colon microbial community in terms of both structure and function: An in vitro analysis. Applied and Experimental Microbiology. https://academic.oup.com/femsec/article/98/5/fiac038/6564177.
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Analysis of the ability of capsaicin to modulate the human gut microbiota in vitro
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Mahalak, K.K., Bobokalonov, J., Firrman, J., Williams, R., Evans, B., Fanelli, B., Soares, J., Liu, L.S., Kobori, M. 2022. Analysis of the ability of capsaicin to modulate the human gut microbiota in vitro. Nutrients. https://doi.org/10.3390/nu14061283.
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Changes to environmental pH alters the colon microbial community in terms of both structure and function: An in vitro analysis
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Environmental pH is a determinant of the gut microbiota community composition and production of short chain fatty acids
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Comparative analysis of the gut microbiota cultured in vitro using a single colon versus a 3-stage colon experimental design
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Firrman, J., Liu, L.S., Mahalak, K.K., Tanes, C., Bittinger, K., Bobokalonov, J., Van Den Abbeele, P., Mattei, L., Zhang, H. 2021. Comparative analysis of the gut microbiota cultured in vitro using a single colon versus a 3-stage colon experimental design. Applied Microbiology and Biotechnology. volume 105, pages 3353–3367. https://link.springer.com/article/10.1007/s00253-021-11241-x.
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Triclosan has a robust, yet reversible impact on human gut microbial composition in vitro.
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Mahalak, K.K., Firrman, J., Lee, J., Bittinger, K., Nunez, A., Bobokalonov, J., Arango-Argoty, G., Zhang, L., Zhang, G., Liu, L.S. 2020. Triclosan has a robust, yet reversible impact on human gut microbial composition in vitro. PLoS One. 15(6): 1-22. https://doi.org/10.1371/journal.pone.0234046.
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Impact of steviol glycosides and erythritol on the human and Cebus apella gut microbiome
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Mahalak, K.K., Firrman, J., Tomasula, M.M., Nunez, A., Lee, J., Bittinger, K., Rinaldi, W., Liu, L.S. 2019. Impact of steviol glycosides and erythritol on the human and Cebus apella gut microbiome. Journal of Agricultural and Food Chemistry. Pages A-I. https://doi.org/10.1021/acs.jafc.9b06181.
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Metagenomic assessment of the Cebus Apella gut microbiota
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Firrman, J., Tanes, C., Bittinger, K., Mahalak, K.K., Rinaldi, W., Liu, L.S. 2019. Metagenomic assessment of the Cebus Apella gut microbiota. American Journal of Primatology. https://doi.org/10.1002/ajp.23023.
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