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Mei Wang
Natural Products Utilization Research
Research Chemist

Phone: (662) 915-1046
Fax:

UNIVERSITY, MS 38677

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Biobased Pesticide Discovery and Product Optimization and Enhancement from Medicinal and Aromatic Crops
In-House Appropriated (D)
  Accession Number: 438514

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
6-Oxofurostane and (iso)spirostane type of saponins in Smilax sieboldii: UHPLC-QToF-MS/MS and GNPS-molecular networking approach for the rapid dereplication and biodistribution of specialized metabolites Reprint Icon - (Peer Reviewed Journal)
Avula, B., Bae, J., Ahn, J., Wang, Y., Wang, M., Kwon, Y., Chittiboyina, A.G., Khan, I.A. 2023. 6-Oxofurostane and (iso)spirostane type of saponins in Smilax sieboldii: UHPLC-QToF-MS/MS and GNPS-molecular networking approach for the rapid dereplication and biodistribution of specialized metabolites. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms241411487.
Chemical characterization and quantitative determination of flavonoids and phenolic acids in yerba santa (Eriodictyon spp.) using UHPLC/DAD/Q-ToF Reprint Icon - (Peer Reviewed Journal)
Wang, M., Zhao, J., Avula, B., Lee, J., Upton, R., Khan, I. 2023. Chemical characterization and quantitative determination of flavonoids and phenolic acids in yerba santa (Eriodictyon spp.) using UHPLC/DAD/Q-ToF. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpba.2023.115570.
Cannabinoid receptor type II ligands from sandalwood oil and synthetic alpha-santalol derivatives Reprint Icon - (Peer Reviewed Journal)
Paudel, P., Pandey, P., Paris, J.J., Ashpole, N.M., Mahdi, F., Tian, J., Lee, J., Wang, M., Xu, M., Chittiboyina, A.G., Khan, I.A., Ross, S.A., Li, X. 2023. Cannabinoid receptor type II ligands from sandalwood oil and synthetic alpha-santalol derivatives. Journal of Natural Products. https://doi.org/10.1021/acs.jnatprod.3c00282.
Chemical characterization and quality assessment of copaiba oil-resin using GS/MS and SFC/MS Reprint Icon - (Peer Reviewed Journal)
Lee, J., Wang, M., Zhao, J., Ali, Z., Hawwal, M., Khan, I. 2023. Chemical characterization and quality assessment of copaiba oil-resin using GS/MS and SFC/MS. Plants. https://doi.org/10.3390/plants12081619.
Yerba santa leaves and tops eriodictyon californicum and related species-standards of identity, purity, analysis, and quality control - (Monograph)
Wang, M. 2023. Yerba santa leaves and tops eriodictyon californicum and related species-standards of identity, purity, analysis, and quality control. American Herbal Pharmacopoeia and Therapeutic Compendium. 1.
Antiplasmodial and antimicrobial activities of ent-abietane diterpenoids from the roots of Suregada zanzibariensis Reprint Icon - (Peer Reviewed Journal)
Matundura, J.O., Midiwo, J.O., Yenesew, A., Omosa, L., Kumarihamy, M., Zhao, J., Wang, M., Tripathi, S., Khan, S., Masila, V.M., Nchiozem-Ngnitedem, V., Muhammad, I. 2022. Antiplasmodial and antimicrobial activities of ent-abietane diterpenoids from the roots of Suregada zanzibariensis. Natural Product Research. https://doi.org/10.1080/14786419.2022.2158463.
Development of a GC/Q-ToF method coupled with headspace solid-phase microextraction to evaluate the in vitro metabolism of ß-Caryophyllene Reprint Icon - (Peer Reviewed Journal)
Lee, J., Wang, M., Mondal, G., Khan, I.A., Yates, C.R. 2022. Development of a GC/Q-ToF method coupled with headspace solid-phase microextraction to evaluate the in vitro metabolism of ß-Caryophyllene. Molecules. https://doi.org/10.3390/molecules27217441.
Synthesis and inhibitory activity of machaeridiol- based novel anti-MRSA and anti-VRE compounds and their profiling for cancer- related signaling pathways Reprint Icon - (Peer Reviewed Journal)
Kumarihamy, M., Tripathi, S., Balachandran, P., Avula, B., Zhao, J., Wang, M., Bennett, M., Carr, M.A., Micheal, L., Ocean, W.I., Marquart, M.E., Nanayakkara, D., Muhammad, I. 2022. Synthesis and inhibitory activity of machaeridiol- based novel anti-MRSA and anti-VRE compounds and their profiling for cancer- related signaling pathways. Molecules. https://doi.org/10.3390/molecules27196604.
Comparative analysis of chemical profiles of Radix Astragali between ultrafine granular powder and traditional sliced mate-rials Reprint Icon - (Peer Reviewed Journal)
Cao, L., Wang, M., Zhao, J., Peng, L., Cheng, J., Qiu, S., Khan, I., Li, X. 2022. Comparative analysis of chemical profiles of Radix Astragali between ultrafine granular powder and traditional sliced mate-rials. Medicinal Plant Biology. https://doi.org/10.48130/MPB-2022-0004.
Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira Reprint Icon - (Peer Reviewed Journal)
Huh, J., Zhang, J., Hauerová, R., Lee, J., Haider, S., Wang, M., Hauer, T., Khan, I., Chittiboyina, A., Pugh, N. 2022. Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira. Scientific Reports. https://doi.org/10.1038/s41598-022-19590-x.
Phytochemical investigation of Egyptian Spinach leaves, a potential source for antileukemic metabolites: in vitro and in silico study Reprint Icon - (Peer Reviewed Journal)
Abdelgawad, S.M., Hetta, M.H., Ibrahim, M.A., Balachandran, P., Zhang, J., Wang, M., Fawzy, G.A., El-Askary, H.I., Ross, S.A. 2022. Phytochemical investigation of Egyptian Spinach leaves, a potential source for antileukemic metabolites: in vitro and in silico study. Revista Brasileira de Farmacognosia. https://doi.org/10.1007/s43450-022-00307-0.
Metabolite variation and discrimination of five licorice (Glycyrrhiza) species: HPTLC and NMR explorations Reprint Icon - (Peer Reviewed Journal)
Zhao, J., Wang, M., Sabastian, J.A., Lee, J., Chittiboyina, A.G., Avula, B., Ali, Z., Li, J., Wu, C., Khan, I. 2022. Metabolite variation and discrimination of five licorice (Glycyrrhiza) species: HPTLC and NMR explorations. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpba.2022.115012.
Chemical authentication and speciation of Salvia botanicals: an investigation utilizing GC/Q-ToF and chemometrics Reprint Icon - (Peer Reviewed Journal)
Lee, J., Wang, M., Jianping, Z., Avula, B., Chittiboyinaa, A.G., Khan, I.A. 2022. Chemical authentication and speciation of Salvia botanicals: an investigation utilizing GC/Q-ToF and chemometrics. Foods. https://doi.org/10.3390/foods11142132.
Phytochemical investigation of Egyptian riverhemp: a potential source of antileukemic metabolites Reprint Icon - (Peer Reviewed Journal)
Abdelgawad, S.M., Hett, M.H., Ibrahima, M.A., Balachandran, P., Zhang, J., Wang, M., Fawzy, G.A., El-Askary, H.I., Ross, S.A. 2022. Phytochemical investigation of Egyptian riverhemp: a potential source of antileukemic metabolites. Journal of Natural Medicine. https://doi.org/10.1155/2022/8766625.
Chemometric analysis and chemical characterization for the botanical identification of Glycyrrhiza species (G. glabra, G. uralensis, G. inflata, G. echinata and G. lepidota) using liquid chromatography-quadrupole time of flig Reprint Icon - (Peer Reviewed Journal)
Avula, B., Bae, J., Chittiboyina, A.G., Wang, Y., Wang, M., Zhao, J., Zulfiqar, A., Li, J., Wu, C., Khan, I.A. 2022. Chemometric analysis and chemical characterization for the botanical identification of Glycyrrhiza species (G. glabra, G. uralensis, G. inflata, G. echinata and G. lepidota) using liquid chromatography-quadrupole time of flig. Journal of Agricultural and Food Chemistry. https://doi.org/10.1016/j.jfca.2022.104679.
Agronomy, chemical analysis, and antidiabetic activity of basil (Ocimum species) Reprint Icon - (Peer Reviewed Journal)
Wang, M., Cantrell, C.L., Matthews, S.T., Paudel, P., Lee, J., Mentreddy, S.R. 2022. Agronomy, chemical analysis, and antidiabetic activity of basil (Ocimum species). Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acsfoodscitech.2c00100?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as.
A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata Reprint Icon - (Peer Reviewed Journal)
Kamau, R.W., Midiwo, J.O., Mgani, Q.A., Masila, V.M., Kumarihamy, M., Wang, M., Zhao, J., Muhamma, I. 2022. A new gnidiflavanone-flavonol dimer and other constituents from Gnidia apiculata. Natural Product Research. https://doi.org/10.1080/14786419.2022.2062349.
Comparative analysis of five salvia species using LC-DAD-QToF Reprint Icon - (Peer Reviewed Journal)
Avula, B., Bae, J., Chittiboyinaa, A.A., Wang, Y., Wang, M., Srivedavyasasri, R., Ali, Z., Li, J., Wu, C., Khan, I.A. 2021. Comparative analysis of five salvia species using LC-DAD-QToF. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpba.2021.114520.
Are atranols the only skin sensitizers in oakmoss, a systematic investigation using non-animal methods Reprint Icon - (Peer Reviewed Journal)
Avonto, C., Chittiboyina, A.G., Khan, S.I., Dale, O.R., Parcher, J.F., Wang, M., Khan, I.A. 2020. Are atranols the only skin sensitizers in oakmoss, a systematic investigation using non-animal methods. Toxicology In Vitro. 70. Article e105053. https://doi.org/10.1016/j.tiv.2020.105053.
NMR technique and methodology in botanical health product analysis and quality control Reprint Icon - (Peer Reviewed Journal)
Zhao, J., Wang, M., Saroja, S.G., Khan, I.A. 2021. NMR technique and methodology in botanical health product analysis and quality control. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpba.2021.114376.
Analysis of docosanol using GC/MS: Method development, validation, and application to ex vivo human skin permeation studies Reprint Icon - (Peer Reviewed Journal)
Shankara, V., Wang, M., Ajjarapua, S., Kolimi, P., Avula, B., Murthy, R., Khan, I., Naraisimha, M. 2021. Analysis of docosanol using GC/MS: Method development, validation, and application to ex vivo human skin permeation studies. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpha.2021.08.004.
Chemical constituents and anti-gastric ulcer activity of essential oils of Alpinia officinarum (Zingiberaceae), Cyperus rotundus (Cyperaceae), and their herbal pair Reprint Icon - (Peer Reviewed Journal)
Huijuan, Q., Lin, K., Li, X., Ou, H., Tan, Y., Wang, M., Wei, N. 2021. Chemical constituents and anti-gastric ulcer activity of essential oils of Alpinia officinarum (Zingiberaceae), Cyperus rotundus (Cyperaceae), and their herbal pair. Chemistry and Biodiversity. https://doi.org/10.1002/cbdv.202100214.
Synthesis and antifungal activity evaluation of phloeodictine analogues Reprint Icon - (Peer Reviewed Journal)
Ravu, R., Jacob, M.R., Khan, S.I., Wang, M., Cao, L., Agarwal, A.K., Clark, A.M., Li, X. 2021. Synthesis and antifungal activity evaluation of phloeodictine analogues. Journal of Natural Products. 84,2129-2137. https://doi.org/10.1021/acs.jnatprod.1c00116.
(E)-2,6,10-Trimethyldodec-8-en-2-ol: An undescribed sesquiterpenoid from copaiba oil Reprint Icon - (Peer Reviewed Journal)
Hawwal, M.F., Ali, Z., Wang, M., Zhao, J., Lee, J., Fantoukh, O.I., Khan, I.A. 2021. (E)-2,6,10-Trimethyldodec-8-en-2-ol: An undescribed sesquiterpenoid from copaiba oil. Molecules. 2021, 26, 4456. https://doi.org/10.3390/molecules26154456.
Chemical profiling and characterization of anthraquinones from two Bulbine species and dietary supplements using liquid chromatography-high resolution mass spectrometry Reprint Icon - (Peer Reviewed Journal)
Avula, B., Bae, J., Wang, Y., Wang, M., Ali, Z., Khan, I.A. 2021. Chemical profiling and characterization of anthraquinones from two Bulbine species and dietary supplements using liquid chromatography-high resolution mass spectrometry. Nature Product Communications. https://doi.org/10.1093/jaoacint/qsab075.
A novel approach for lavender essential oil authentication and quality assessment Reprint Icon - (Peer Reviewed Journal)
Wang, M., Zhao, J., Ali, Z., Avonto, C., Khan, I. 2021. A novel approach for lavender essential oil authentication and quality assessment. Journal of Pharmaceutical and Biomedical Analysis. 199. Article e114050. https://doi.org/10.1016/j.jpba.2021.114050.
Quantitative determination and characterization of polyphenols from Cissus quadrangularis L. and dietary supplements using UHPLC-PDA-MS, LC-QToF and HPTLC Reprint Icon - (Peer Reviewed Journal)
Avula, B., Bae, J., Zhao, J., Wang, Y., Wang, M., Zhang, Z., Ali, Z., Khan, I. 2021. Quantitative determination and characterization of polyphenols from Cissus quadrangularis L. and dietary supplements using UHPLC-PDA-MS, LC-QToF and HPTLC. Journal of Pharmaceutical and Biomedical Analysis. https://doi.org/10.1016/j.jpba.2021.114036.
Cross talk of cancer signaling pathways by cyclic hexapeptides and anthraquinones from Rubia cordifolia Reprint Icon - (Peer Reviewed Journal)
Balachandran, P., Ibrahim, M.A., Zhang, J., Wang, M., Pasco, D.S., Muhammad, I. 2021. Cross talk of cancer signaling pathways by cyclic hexapeptides and anthraquinones from Rubia cordifolia. Molecules. 26/735. https://doi.org/10.3390/molecules26030735.
Antimicrobial constituents from Machaerium Pers.: Inhibitory activities and synergism of machaeriols and machaeridiols against methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecium and perm Reprint Icon - (Peer Reviewed Journal)
Muhammad, I., Jacob, M.R., Ibrahim, M.A., Raman, V., Kumarihamy, M., Wang, M., Al-Adhami, T., Hind, C., Clifford, M., Martin, B., Sutton, M., Rahman, M., Zhao, J. 2020. Antimicrobial constituents from Machaerium Pers.: Inhibitory activities and synergism of machaeriols and machaeridiols against methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecium and perm. Molecules. 25/6000. https://doi.org/10.3390/molecules25246000.
Phenolic contents, chemical profiling, in silico and in vitro antiinflammatory and anticancer properties of Alnus nitida (Spach) Endl Reprint Icon - (Peer Reviewed Journal)
Shaukat, U., Ahemad, S., Wang, M., Khan, S.I., Ali, Z., Muhammad I, T.I., Abdallah, H.H., Khan, I.A., Saleem, M., Mahomoodally, M.F. 2021. Phenolic contents, chemical profiling, in silico and in vitro antiinflammatory and anticancer properties of Alnus nitida (Spach) Endl. South African Journal of Botany. 138:148-155. https://doi.org/10.1016/j.sajb.2020.12.010.
Newly generated Atractylon derivatives in the processed rhizomes of Atractylodes macrocephala Koidz Reprint Icon - (Peer Reviewed Journal)
Zhai, C., Zhao, J., Chittiboyina, A.G., Meng, Y., Wang, M., Khan, S.I., Khan, I.A. 2020. Newly generated Atractylon derivatives in the processed rhizomes of Atractylodes macrocephala Koidz. Molecules. https://doi.org/10.3390/molecules25245904.
Comparative study and quality evaluation regarding morphology characters, volatile constituents and triglycerides in seeds of five species used in traditional Chinese medicine Reprint Icon - (Peer Reviewed Journal)
Wei, N., Wang, M., Adams, S.J., Yu, P., Avula, B., Wang, Y., Pan, K., Wang, Y., Khan, I.A. 2020. Comparative study and quality evaluation regarding morphology characters, volatile constituents and triglycerides in seeds of five species used in traditional Chinese medicine. Journal of Pharmaceutical and Biomedical Analysis. 194. Article e113801. https://doi.org/10.1016/j.jpba.2020.113801.
Effects of Euphorbia umbellata extracts on complement activation and chemotaxis of neutrophils Reprint Icon - (Peer Reviewed Journal)
De Oliveira, T.L., Fontana, P.D., Bavia, L., Cruz, L., Crisma, A.R., Sassaki, G.L., Menezes, L.R., Wang, M., Beltrame, F., Messias-Reason, I.J. 2020. Effects of Euphorbia umbellata extracts on complement activation and chemotaxis of neutrophils. Journal of Ethnopharmacology. 265/113348. https://doi.org/10.1016/j.jep.2020.113348.
Identification of antifungal bisphosphocholines from medicinal Gentiana species Reprint Icon - (Peer Reviewed Journal)
Ren, S., Deng, K., Qiu, S., Wang, M., Avula, B., Tripathi, S.K., Jacob, M.R., Gong, L., Wang, W., Khan, I.A., Li, X. 2020. Identification of antifungal Bisphosphocholines from medicinal Gentiana species. Journal of Natural Products. 2020, 83, 10, 3207–3211. https://doi.org/10.1021/acs.jnatprod.0c00584.
A comprehensive workflow for the analysis of Bio-Macromolecular supplements: Case Study of 20 Whey protein products Reprint Icon - (Peer Reviewed Journal)
Avula, B., Parveen, I., Zhao, J., Wang, M., Techen, N., Wang, Y., Riaz, M., Bae, J., Shami, A.A., Chittiboyina, A.G., Khan, I.A., Sharp, J.S. 2021. A comprehensive workflow for the analysis of Bio-Macromolecular supplements: Case Study of 20 Whey protein products. Journal of Dietary Supplement. https://doi.org/10.1080/19390211.2021.1897724.