Edmund Norris

Research Chemist

Edmund Norris

Research Entomologist

Telephone: (352) 374 - 5919

Email: edmund.norris@usda.gov

Google Scholar

CV Links
Education | Research Focus | Lab Members
Research Experience | Memberships
Patents | Invited Presentations
Publications

Education

Research Focus

Our lab is interested in the development of novel repellents and insecticidal formulations that may circumvent insecticide resistance, while primarily focusing on natural products as our inspiration. Our research focuses on better understanding the mechanisms of novel repellent, insecticidal, and synergistic agents using a variety of electrophysiolgical, pharmacological, and biochemical techniques.

Lab Members

Greg Allen
Jedidiah Kline
Shawn Culley

Research Experience

Research and Product Development, Clarke Mosquito Control Products, 2011 - 2012
Research Associate I, Pesticide Toxicology Laboratory, July 2012 - December 2013
Graduate Research Assistant, Pesticide Toxicology Laboratory, Ames, IA, 2014 - 2018
Laboratory Supervisor, Pesticide Toxicology Laboratory, 2015 - 2018
Post-doctoral Research Associate, Bloomquist Toxicology Laboratory, September 2018 - September 2020
USDA Chemist/Entomologist, September 2020 - Current

Membership in Professional Societies

American Mosquito Control Association – AMCA
Entomological Society of America – ESA
American Chemical Society – Agrochemicals Division of ACS
Society of Vector Ecology – SOVE

Patents (Current and Pending)

1. Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as seed treatments. Joel R. Coats, James S. Klimavicz, Edmund J. Norris, A. D. Lindsay, Steven. M. Bessette International Application #PCT/US17/48291
2. Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as herbicides. Joel R. Coats, James S. Klimavicz, Edmund J. Norris, A. D. Lindsay, Steven. M. Bessette. International Application #PCT/US17/48290
3. Monoterpenoid/phenylpropanoid-containing compounds and methods of their making and use as insecticidal baits. Joel R. Coats, James S. Klimavicz, Edmund J. Norris, A. D. Lindsay, Steven. M. Bessette International Application # PCT/US17/48293
4. Insect repellent compounds and compositions, and methods thereof. Joel R. Coats, Edmund J. Norris, James S. Klimavicz. US Patent Application # 15684770
5. Natural derivatives and methods of using the same. George A. Kraus, Joel R. Coats, Edmund J Norris, Yang Qu. US Patent Application #20200024246A1
6. Methods of Using Pogostone as an Herbicide. George A. Kraus, Joel R. Coats, Edmund J Norris. US Provisional Patent Application #62/797,760
7. Synergistic and Residual Pesticidal Compositions. J. Coats, E. Norris, Bessette, S. O’Connor, G. US Provisional Patent Application #62838484
8. COMPOSITIONS AND METHODS RELATING TO INSECTICIDES. Jeffrey R. Bloomquist, E. J. Norris. US Provisional Patent Application #62823796
9. Synergistic Mixtures for Arthropod Toxicity and Repellency Liu Yang, Gary Richoux Jr., Edmund J. Norris, Jeffrey R. Bloomquist. US Provisional Patent Application #62/880,503
10. COMPOSITIONS AND METHODS RELATING TO INSECTICIDES. Jeffrey R. Bloomquist, E. J. Norris. US Provisional Patent Application # 62890808
11. Synergistic Mixtures Comprising Pyrethrum for Arthropod Toxicity and Repellency. Jeffrey R. Bloomquist, E. J. Norris. US Provisional Patent Application # 63/143,581

Invited Presentaions

1. Edmund J Norris, Quentin R. R. Coquerel, Fabien Démares, Werner J. Geldenhuys, Anne-Marie Le Ray, Dimitri Bréard, Pascal Richomme, Christian Legros, Jeffrey R. Bloomquist. Neurophysiological and insecticidal effects of liriodenine, an alkaloid isolated from the Chinese herb Zanthoxylum nitidum. American Chemical Society – AgroChemicals Division. August 2021.
2. Edmund J Norris. Developing Biorational Repellents and Insecticides. W4045 Agrochemical Impacts on Human And Environmental Health: Mechanisms And Mitigation Annual Meeting. Virtual Meeting – August 2021.
3. Edmund J Norris, Jeffrey Bloomquist. DFDT (p-p’-difluoro-DDT) as an antimalarial mosquitocide. March Malaria Madness Meeting – Virtual Symposium. February 2021.
4. Edmund J Norris, Jeffrey Bloomquist. Target-site Mechanism of Action of Resistance Breaking Natural Products. American Chemical Society – AgroChemicals Division. August 2020.
5. Edmund J. Norris, Adam Mullis, Caleb Corona, Balaji Narasimhan, Lyric Bartholomay, Joel R. Coats. Distribution of biodegradable nano- and microparticles in Aedes aegypti tissues. Entomological Society of America. St. Louis, MO. November 2019.
6. Edmund J. Norris, Jeffrey Bloomquist. Plant essential oils enhance public health insecticides through diverse modes of action. American Chemical Society – AgroChemicals Division. August 2019.
7. Edmund J. Norris, Jeffrey Bloomquist. Natural and synthetic compounds display multiple mechanisms of synergism and resistance-breaking properties. American Chemical Society – AgroChemicals Division. August 2019.
8. Edmund Norris, Jeffrey Bloomquist. Fir needle plant essential oil significantly increases knockdown, but not toxicity, of diverse public health insecticides against Aedes aegypti. St. Augustine Mosquito Control Workshop. March 2019.
9. Edmund Norris, Maria Archevald-Cansobre, Aaron D Gross, Lyric Bartholomay, Joel R. Coats. Phytochemical synergists: Plant oils inhibit detoxification enzymes in the yellow fever mosquito. Entomological Society of America. Vancouver, BC. November 2018.
10. Edmund Norris. Panel Member. INSecticide TARgets Symposium Summit. American Chemical Society. Boston, MA. August 2018.
11. Edmund Norris, Aaron D. Gross, Lyric Bartholomay, Joel Coats. Phytochemical synergists for insecticides: Replacement for piperonyl butoxide. Entomological Society of America. Denver, CO. November 2017.
12. Edmund Norris, Maria Archevald-Cansobre, Aaron D Gross, Lyric Bartholomay, Joel R. Coats. Plant oils are capable of enhancing diverse insecticides against susceptible and resistant strains of mosquitoes. American Society of Tropical Medicine and Hygiene. Baltimore, MD. November 2017.
13. Edmund Norris, Maria Archevald-Cansobre, Aaron D. Gross, Lyric C. Bartholomay, Joel R. Coats. Plant oils are capable of enhancing diverse insecticides against susceptible and resistant strains of mosquitoes. Society of Vector Ecology. Mallorca, Spain. September 2017.
14. Edmund Norris, Maria Archevald-Cansobre, Aaron D. Gross, Lyric C. Bartholomay, Joel R. Coats. Phytochemical synergists: Natural plant oils as synergists for diverse pyrethroids. American Chemical Society – AgroChemicals Division. Washington, DC. August 2017.
15. Edmund Norris, Joel R. Coats, James Klimavicz, Lyric Bartholomay. Biorepellents: Natural and Biorational terpenes. International Congress of Entomology. Repellents Symposium. International Congress of Entomology. Orlando, FL. October 2016.

Selected Publications

1. Norris, E.J. and Bloomquist, J.R., 2022. Sodium channel-directed alkaloids synergize the mosquitocidal and neurophysiological effects of natural pyrethrins. Pesticide Biochemistry and Physiology, 186, p.105171.
2. Norris, E.J., Chen, R., Li, Z., Geldenhuys, W., Bloomquist, J.R. and Swale, D.R., 2022. Mode of action and toxicological effects of the sesquiterpenoid, nootkatone, in insects. Pesticide Biochemistry and Physiology, 183, p.105085.
3. Norris, E.J. and Bloomquist, J.R., 2022. Nutritional status significantly affects toxicological endpoints in the CDC bottle bioassay. Pest Management Science, 78(2), pp.743-748.
4. Bloomquist, J., Jiang, S., Norris, E., Richoux, G., Yang, L. and Linthicum, K.J., 2022. Novel pyrethroid derivatives as effective mosquito repellents and repellent synergists. In Advances in Arthropod Repellents (pp. 19-32). Academic Press.
5. Norris, E.J. and Bloomquist, J.R., 2021. Recording central neurophysiological output from mosquito larvae for neuropharmacological and insecticide resistance studies. Journal of Insect Physiology, 135, p.104319.
6. Coquerel, Q.R., Démares, F., Geldenhuys, W.J., Le Ray, A.M., Bréard, D., Richomme, P., Legros, C., Norris, E. and Bloomquist, J.R., 2021. Toxicity and mode of action of the aporphine plant alkaloid liriodenine on the insect GABA receptor. Toxicon, 201, pp.141-147.
7. Richoux, G.M., Yang, L., Norris, E., Jiang, S., Linthicum, K.J. and Bloomquist, J.R., 2021. Resistance-breaking insecticidal activity of new spatial insecticides against Aedes aegypti. Journal of Agricultural and Food Chemistry, 69(33), pp.9684-9692.
8. Yang, L., Demares, F., Norris, E.J., Jiang, S., Bernier, U.R. and Bloomquist, J.R., 2021. Bioactivities and modes of action of VUAA1. Pest Management Science, 77(8), pp.3685-3692.
9. Norris, E.J. and Bloomquist, J.R., 2021. Co-toxicity factor analysis reveals numerous plant essential oils are synergists of natural pyrethrins against aedes aegypti mosquitoes. Insects, 12(2), p.154.
10. Cuba, I.H., Richoux, G.R., Norris, E.J., Bernier, U.R., Linthicum, K.J. and Bloomquist, J.R., 2021. Vapor phase repellency and insecticidal activity of pyridinyl amides against anopheline mosquitoes. Current Research in Parasitology & Vector-borne Diseases, 1, p.100062.
11. Richoux, G.M., Yang, L., Norris, E.J., Tsikolia, M., Jiang, S., Linthicum, K.J. and Bloomquist, J.R., 2020. Structure–activity relationship analysis of potential new vapor-active insect repellents. Journal of Agricultural and Food Chemistry, 68(47), pp.13960-13969.
12. Norris, E.J., Demares, F., Zhu, X. and Bloomquist, J.R., 2020. Mosquitocidal activity of p, p’-difluoro-diphenyl-trichloroethane (DFDT). Pesticide Biochemistry and Physiology, 170, p.104686.
13. St. Clair, C.R., Norris, E.J., Masloski, K.E., Coats, J.R. and Gassmann, A.J., 2020. Evaluation of pyrethroids and organophosphates in insecticide mixtures for management of western corn rootworm larvae. Pest Management Science, 76(11), pp.3871-3878.
14. Xiang, C., Etrick, N.R., Frey, M.W., Norris, E.J. and Coats, J.R., 2020. Structure and properties of polyamide fabrics with insect-repellent functionality by electrospinning and oxygen plasma-treated surface coating. Polymers, 12(10), p.2196.
15. Norris, E.J., Mullis, A.S., Phanse, Y., Narasimhan, B., Coats, J.R. and Bartholomay, L.C., 2020. Biodistribution of degradable polyanhydride particles in Aedes aegypti tissues. PLoS Neglected Tropical Diseases, 14(9), p.e0008365.
16. Yang, L., Richoux, G.M., Norris, E.J., Cuba, I., Jiang, S., Coquerel, Q., Demares, F., Linthicum, K.J. and Bloomquist, J.R., 2020. Pyrethroid-derived acids and alcohols: bioactivity and synergistic effects on mosquito repellency and toxicity. Journal of agricultural and food chemistry, 68(10), pp.3061-3070.
17. Yang, L., Norris, E.J., Jiang, S., Bernier, U.R., Linthicum, K.J. and Bloomquist, J.R., 2020. Reduced effectiveness of repellents in a pyrethroid‐resistant strain of Aedes aegypti (Diptera: culicidae) and its correlation with olfactory sensitivity. Pest management science, 76(1), pp.118-124.
18. Norris, E.J., Gross, A.D., Bartholomay, L.C. and Coats, J.R., 2019. Plant essential oils synergize various pyrethroid insecticides and antagonize malathion in Aedes aegypti. Medical and veterinary entomology, 33(4), pp.453-466.
19. Annandarajah, C., Norris, E.J., Funk, R., Xiang, C., Grewell, D., Coats, J.R., Mishek, D. and Maloy, B., 2019. Biobased plastics with insect‐repellent functionality. Polymer Engineering & Science, 59(s2), pp.E460-E467.
20. Norris, E.J., Johnson, J.B., Gross, A.D., Bartholomay, L.C. and Coats, J.R., 2018. Plant essential oils enhance diverse pyrethroids against multiple strains of mosquitoes and inhibit detoxification enzyme processes. Insects, 9(4), p.132.