Location: Produce Safety and Microbiology ResearchTitle: Draft genome sequences of nine Campylobacter hyointestinalis subsp. lawsonii strains Author
|Bian, Xiaoming - University Of Georgia|
|Szymanski, Christine - University Of Alberta|
|Miller, William - Bill|
Submitted to: MICROBIOLOGY RESOURCE ANNOUNCEMENTS
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/5/2018
Publication Date: 9/13/2018
Citation: Bian, X., Huynh, S., Chapman, M.H., Szymanski, C., Parker, C., Miller, W.G. 2018. Draft genome sequences of nine Campylobacter hyointestinalis subsp. lawsonii strains. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. 7(10): e01016-18.
Interpretive Summary: Campylobacter hyointestinalis is typically associated with livestock. There are two subspecies of C. hyointestinalis: hyointestinalis, whose host is primarily cattle, and lawsonii, whose host is primarily swine. Recently, however, C. hyointestinalis infections have been reported increasingly in humans and may cause serious gastrointestinal illness. In order to detect this emerging pathogen, molecular methods have been developed. Although these methods work well for subsp. hyointestinalis strains, their efficacy in detecting subsp. lawsonii is spotty, primarily because the methods developed for this subspecies were based on the DNA sequence of a single strain. Here we present the DNA sequences of an additional nine lawsonii strains. This set of strains possesses enough sequence variation to permit the development of a much more robust detection method for lawsonii in human clinical samples, the food chain and the environment.
Technical Abstract: With increasing reports of Campylobacter hyointestinalis species associated with human diseases, more genome sequences are required to understand the virulence mechanisms of this emerging pathogen. Here we report the genome sequences of nine C. hyointestinalis subsp. lawsonii strains.